Basic Information
Gene ID 102423996
Gene Name STAT5A
Full Name Signal transducer and activator of transcription
Organism Myotis lucifugus [59463]

Cross Reference
UniProt G1QCS5 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMLUP00000021508 Gene3D G3DSA:1.10.238.10 IPR011992 472 597 5.60e-46 EF-hand domain pair
ENSMLUP00000021508 Gene3D G3DSA:1.10.532.10 IPR013799 1 125 9.10e-49 STAT transcription factor, protein interaction
ENSMLUP00000021508 Gene3D G3DSA:1.20.1050.20 IPR013800 139 332 3.80e-65 STAT transcription factor, all-alpha
ENSMLUP00000021508 Gene3D G3DSA:2.60.40.630 IPR012345 333 471 2.60e-69 STAT transcription factor, DNA-binding, subdomain
ENSMLUP00000021508 Gene3D G3DSA:3.30.505.10 IPR000980 598 712 6.90e-40 SH2 domain
ENSMLUP00000021508 PANTHER PTHR11801 IPR001217 2 778 0.00e-00 Transcription factor STAT
ENSMLUP00000021508 Pfam PF00017 IPR000980 595 668 1.20e-10 SH2 domain
ENSMLUP00000021508 Pfam PF01017 IPR013800 138 330 1.00e-54 STAT transcription factor, all-alpha
ENSMLUP00000021508 Pfam PF02864 IPR013801 332 583 4.20e-99 STAT transcription factor, DNA-binding
ENSMLUP00000021508 Pfam PF02865 IPR013799 2 125 1.80e-48 STAT transcription factor, protein interaction
ENSMLUP00000021508 ProSiteProfiles PS50001 IPR000980 589 686 0.00e-00 SH2 domain
ENSMLUP00000021508 SMART SM00252 IPR000980 587 688 2.00e-08 SH2 domain
ENSMLUP00000021508 SMART SM00964 IPR013799 2 126 3.70e-65 STAT transcription factor, protein interaction
ENSMLUP00000021508 SUPERFAMILY SSF47655 IPR015988 136 332 0.00e-00 STAT transcription factor, coiled coil
ENSMLUP00000021508 SUPERFAMILY SSF48092 IPR013799 1 124 0.00e-00 STAT transcription factor, protein interaction
ENSMLUP00000021508 SUPERFAMILY SSF49417 IPR008967 327 584 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMLUP00000021508 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSMLUP00000021508 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSMLUP00000021508 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSMLUP00000021508 PF00017 7.5e-12 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMLUP00000021508 GO:0001553 biological_process luteinization
ENSMLUP00000021508 GO:0001779 biological_process natural killer cell differentiation
ENSMLUP00000021508 GO:0006351 biological_process transcription, DNA-templated
ENSMLUP00000021508 GO:0007259 biological_process JAK-STAT cascade
ENSMLUP00000021508 GO:0007565 biological_process female pregnancy
ENSMLUP00000021508 GO:0007595 biological_process lactation
ENSMLUP00000021508 GO:0019218 biological_process regulation of steroid metabolic process
ENSMLUP00000021508 GO:0019915 biological_process lipid storage
ENSMLUP00000021508 GO:0030155 biological_process regulation of cell adhesion
ENSMLUP00000021508 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSMLUP00000021508 GO:0038161 biological_process prolactin signaling pathway
ENSMLUP00000021508 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSMLUP00000021508 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSMLUP00000021508 GO:0043029 biological_process T cell homeostasis
ENSMLUP00000021508 GO:0043066 biological_process negative regulation of apoptotic process
ENSMLUP00000021508 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSMLUP00000021508 GO:0045579 biological_process positive regulation of B cell differentiation
ENSMLUP00000021508 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSMLUP00000021508 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSMLUP00000021508 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMLUP00000021508 GO:0046543 biological_process development of secondary female sexual characteristics
ENSMLUP00000021508 GO:0050729 biological_process positive regulation of inflammatory response
ENSMLUP00000021508 GO:0005634 cellular_component nucleus
ENSMLUP00000021508 GO:0005737 cellular_component cytoplasm
ENSMLUP00000021508 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMLUP00000021508 GO:0004871 molecular_function signal transducer activity
ENSMLUP00000021508 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100161101 9555 Papio anubis 100998364
10029 Cricetulus griseus 100755571 34638 Metaseiulus occidentalis 100907258
30611 Otolemur garnettii 100958999 9597 Pan paniscus 100988550
9669 Mustela putorius furo 101691575 7719 Ciona intestinalis 778770
9913 Bos taurus ENSBTAG00000009496 9483 Callithrix jacchus ENSCJAG00000000426
51511 Ciona savignyi ENSCSAVG00000011110 9365 Erinaceus europaeus ENSEEUG00000003642
9371 Echinops telfairi ENSETEG00000008535 9785 Loxodonta africana ENSLAFG00000014055
9315 Macropus eugenii ENSMEUG00000006640 42254 Sorex araneus ENSSARG00000014229
9739 Tursiops truncatus ENSTTRG00000007155 8083 Xiphophorus maculatus ENSXMAG00000005165
9598 Pan troglodytes 454681 9544 Macaca mulatta 574129
10020 Dipodomys ordii ENSDORG00000000303 9685 Felis catus ENSFCAG00000002153
9813 Procavia capensis ENSPCAG00000010107 7757 Petromyzon marinus ENSPMAG00000009008
10116 Rattus norvegicus ENSRNOG00000019496 43179 Ictidomys tridecemlineatus ENSSTOG00000006713

Paralogs
ENSMLUG00000012050