Basic Information | |||
Gene ID | ENSXETG00000024399 | ||
Gene Name | thra | ||
Full Name | Thyroid hormone receptor alpha | ||
Organism | Xenopus tropicalis [8364] |
Cross Reference | |||
UniProt | B3GR07 | UniGene | Str.52011 |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSXETP00000052774 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 137 | 416 | 1.50e-78 | Nuclear hormone receptor, ligand-binding |
ENSXETP00000052774 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 58 | 136 | 1.90e-28 | Zinc finger, NHR/GATA-type |
ENSXETP00000052774 | Pfam | PF00104 | IPR000536 | 213 | 385 | 3.50e-25 | Nuclear hormone receptor, ligand-binding, core |
ENSXETP00000052774 | Pfam | PF00105 | IPR001628 | 60 | 129 | 1.60e-29 | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | PRINTS | PR00047 | IPR001628 | 112 | 120 | 1.70e-18 | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | PRINTS | PR00047 | IPR001628 | 120 | 128 | 1.70e-18 | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | PRINTS | PR00047 | IPR001628 | 61 | 77 | 1.70e-18 | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | PRINTS | PR00047 | IPR001628 | 77 | 92 | 1.70e-18 | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | PRINTS | PR00398 | IPR001723 | 124 | 134 | 7.40e-31 | Steroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00398 | IPR001723 | 229 | 250 | 7.40e-31 | Steroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00398 | IPR001723 | 250 | 266 | 7.40e-31 | Steroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00398 | IPR001723 | 317 | 332 | 7.40e-31 | Steroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00398 | IPR001723 | 374 | 391 | 7.40e-31 | Steroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 126 | 142 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 143 | 161 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 166 | 183 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 189 | 208 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 226 | 247 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 252 | 271 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 317 | 339 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 49 | 63 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | PRINTS | PR00546 | IPR001728 | 87 | 98 | 1.40e-100 | Thyroid hormone receptor |
ENSXETP00000052774 | ProSitePatterns | PS00031 | IPR001628 | 61 | 87 | - | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | ProSiteProfiles | PS51030 | IPR001628 | 58 | 135 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | SMART | SM00399 | IPR001628 | 58 | 131 | 2.20e-39 | Zinc finger, nuclear hormone receptor-type |
ENSXETP00000052774 | SMART | SM00430 | IPR000536 | 228 | 386 | 4.60e-34 | Nuclear hormone receptor, ligand-binding, core |
ENSXETP00000052774 | SUPERFAMILY | SSF48508 | IPR008946 | 169 | 413 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSXETP00000052774 | PF00105 | 8.2e-30 | zf-C4 | Zinc finger, C4 type (two domains) |
ENSXETP00000052774 | PF00104 | 1.7e-25 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSXETP00000052774 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSXETP00000052774 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSXETP00000052774 | GO:0030522 | biological_process | intracellular receptor signaling pathway |
ENSXETP00000052774 | GO:0043401 | biological_process | steroid hormone mediated signaling pathway |
ENSXETP00000052774 | GO:0005634 | cellular_component | nucleus |
ENSXETP00000052774 | GO:0003677 | molecular_function | DNA binding |
ENSXETP00000052774 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSXETP00000052774 | GO:0003707 | molecular_function | steroid hormone receptor activity |
ENSXETP00000052774 | GO:0004887 | molecular_function | thyroid hormone receptor activity |
ENSXETP00000052774 | GO:0008270 | molecular_function | zinc ion binding |
ENSXETP00000052774 | GO:0043565 | molecular_function | sequence-specific DNA binding |
ENSXETP00000052774 | GO:0046872 | molecular_function | metal ion binding |
ENSXETP00000052774 | GO:0070324 | molecular_function | thyroid hormone binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
10224 | Saccoglossus kowalevskii | 100313752 | 9597 | Pan paniscus | 100971326 |
8083 | Xiphophorus maculatus | 102237580 | 7897 | Latimeria chalumnae | 102345437 |
9606 | Homo sapiens | 7067 | 10116 | Rattus norvegicus | 81812 |
9615 | Canis familiaris | ENSCAFG00000016173 | 9796 | Equus caballus | ENSECAG00000011120 |
9031 | Gallus gallus | ENSGALG00000000270 | 9544 | Macaca mulatta | ENSMMUG00000002931 |
13616 | Monodelphis domestica | ENSMODG00000013018 | 9669 | Mustela putorius furo | ENSMPUG00000014923 |
61853 | Nomascus leucogenys | ENSNLEG00000001519 | 9978 | Ochotona princeps | ENSOPRG00000012107 |
8128 | Oreochromis niloticus | 100702192 | 10029 | Cricetulus griseus | 100770653 |
31033 | Takifugu rubripes | 101065807 | 9685 | Felis catus | 101095056 |
9595 | Gorilla gorilla | 101143950 | 43179 | Ictidomys tridecemlineatus | 101972353 |
10090 | Mus musculus | 21833 | 28377 | Anolis carolinensis | ENSACAG00000002898 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000007644 | 10141 | Cavia porcellus | ENSCPOG00000015132 |
9361 | Dasypus novemcinctus | ENSDNOG00000017243 | 9371 | Echinops telfairi | ENSETEG00000013166 |
69293 | Gasterosteus aculeatus | ENSGACG00000003766 | 8049 | Gadus morhua | ENSGMOG00000002108 |
9785 | Loxodonta africana | ENSLAFG00000026002 | 8090 | Oryzias latipes | ENSORLG00000012005 |
9813 | Procavia capensis | ENSPCAG00000001185 | 9598 | Pan troglodytes | ENSPTRG00000009112 |
99883 | Tetraodon nigroviridis | ENSTNIG00000011162 |
Paralogs | |||
ENSXETG00000003871 |