Basic Information | |||
Gene ID | ENSGALG00000000270 | ||
Gene Name | THRA | ||
Full Name | Thyroid hormone receptor alpha | ||
Organism | Gallus gallus [9031] |
Cross Reference | |||
UniProt | H9KYR9 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSGALP00000000351 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 127 | 405 | 1.40e-78 | Nuclear hormone receptor, ligand-binding |
ENSGALP00000000351 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 49 | 126 | 2.60e-28 | Zinc finger, NHR/GATA-type |
ENSGALP00000000351 | Pfam | PF00104 | IPR000536 | 203 | 375 | 6.70e-24 | Nuclear hormone receptor, ligand-binding, core |
ENSGALP00000000351 | Pfam | PF00105 | IPR001628 | 50 | 119 | 1.20e-29 | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | PRINTS | PR00047 | IPR001628 | 102 | 110 | 3.90e-19 | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | PRINTS | PR00047 | IPR001628 | 110 | 118 | 3.90e-19 | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | PRINTS | PR00047 | IPR001628 | 51 | 67 | 3.90e-19 | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | PRINTS | PR00047 | IPR001628 | 67 | 82 | 3.90e-19 | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | PRINTS | PR00398 | IPR001723 | 114 | 124 | 8.10e-31 | Steroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00398 | IPR001723 | 219 | 240 | 8.10e-31 | Steroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00398 | IPR001723 | 240 | 256 | 8.10e-31 | Steroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00398 | IPR001723 | 307 | 322 | 8.10e-31 | Steroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00398 | IPR001723 | 364 | 381 | 8.10e-31 | Steroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 116 | 132 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 133 | 151 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 156 | 173 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 179 | 198 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 216 | 237 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 242 | 261 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 307 | 329 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 39 | 53 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | PRINTS | PR00546 | IPR001728 | 77 | 88 | 1.00e-100 | Thyroid hormone receptor |
ENSGALP00000000351 | ProSitePatterns | PS00031 | IPR001628 | 51 | 77 | - | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | ProSiteProfiles | PS51030 | IPR001628 | 48 | 125 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | SMART | SM00399 | IPR001628 | 48 | 121 | 4.10e-39 | Zinc finger, nuclear hormone receptor-type |
ENSGALP00000000351 | SMART | SM00430 | IPR000536 | 218 | 376 | 2.40e-35 | Nuclear hormone receptor, ligand-binding, core |
ENSGALP00000000351 | SUPERFAMILY | SSF48508 | IPR008946 | 159 | 403 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSGALP00000000351 | PF00105 | 5.7e-30 | zf-C4 | Zinc finger, C4 type (two domains) |
ENSGALP00000000351 | PF00104 | 3.6e-24 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSGALP00000000351 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSGALP00000000351 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSGALP00000000351 | GO:0030522 | biological_process | intracellular receptor signaling pathway |
ENSGALP00000000351 | GO:0043401 | biological_process | steroid hormone mediated signaling pathway |
ENSGALP00000000351 | GO:0005634 | cellular_component | nucleus |
ENSGALP00000000351 | GO:0003677 | molecular_function | DNA binding |
ENSGALP00000000351 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSGALP00000000351 | GO:0003707 | molecular_function | steroid hormone receptor activity |
ENSGALP00000000351 | GO:0004887 | molecular_function | thyroid hormone receptor activity |
ENSGALP00000000351 | GO:0008270 | molecular_function | zinc ion binding |
ENSGALP00000000351 | GO:0043565 | molecular_function | sequence-specific DNA binding |
ENSGALP00000000351 | GO:0046872 | molecular_function | metal ion binding |
ENSGALP00000000351 | GO:0070324 | molecular_function | thyroid hormone binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
13735 | Pelodiscus sinensis | 102448851 | 10224 | Saccoglossus kowalevskii | 100313752 |
9483 | Callithrix jacchus | 100394325 | 9103 | Meleagris gallopavo | 100545018 |
8128 | Oreochromis niloticus | 100702192 | 10029 | Cricetulus griseus | 100770653 |
9597 | Pan paniscus | 100971326 | 9555 | Papio anubis | 101007506 |
39432 | Saimiri boliviensis | 101050682 | 31033 | Takifugu rubripes | 101065807 |
9685 | Felis catus | 101095056 | 9595 | Gorilla gorilla | 101143950 |
43179 | Ictidomys tridecemlineatus | 101972353 | 8083 | Xiphophorus maculatus | 102237580 |
7897 | Latimeria chalumnae | 102345437 | 10090 | Mus musculus | 21833 |
7668 | Strongylocentrotus purpuratus | 584535 | 9606 | Homo sapiens | 7067 |
10116 | Rattus norvegicus | 81812 | 28377 | Anolis carolinensis | ENSACAG00000002898 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000007644 | 9913 | Bos taurus | ENSBTAG00000017802 |
9615 | Canis familiaris | ENSCAFG00000016173 | 9358 | Choloepus hoffmanni | ENSCHOG00000000987 |
7719 | Ciona intestinalis | ENSCING00000021968 | 10141 | Cavia porcellus | ENSCPOG00000015132 |
51511 | Ciona savignyi | ENSCSAVG00000006056 | 9361 | Dasypus novemcinctus | ENSDNOG00000017243 |
10020 | Dipodomys ordii | ENSDORG00000004966 | 9796 | Equus caballus | ENSECAG00000011120 |
9365 | Erinaceus europaeus | ENSEEUG00000005916 | 9371 | Echinops telfairi | ENSETEG00000013166 |
69293 | Gasterosteus aculeatus | ENSGACG00000003766 | 8049 | Gadus morhua | ENSGMOG00000016130 |
9785 | Loxodonta africana | ENSLAFG00000026002 | 9315 | Macropus eugenii | ENSMEUG00000010735 |
30608 | Microcebus murinus | ENSMICG00000011433 | 9544 | Macaca mulatta | ENSMMUG00000002931 |
13616 | Monodelphis domestica | ENSMODG00000013018 | 61853 | Nomascus leucogenys | ENSNLEG00000001519 |
9258 | Ornithorhynchus anatinus | ENSOANG00000012237 | 30611 | Otolemur garnettii | ENSOGAG00000002010 |
9978 | Ochotona princeps | ENSOPRG00000012107 | 8090 | Oryzias latipes | ENSORLG00000012005 |
9813 | Procavia capensis | ENSPCAG00000001185 | 9601 | Pongo abelii | ENSPPYG00000014063 |
9598 | Pan troglodytes | ENSPTRG00000009112 | 132908 | Pteropus vampyrus | ENSPVAG00000001768 |
42254 | Sorex araneus | ENSSARG00000013590 | 9305 | Sarcophilus harrisii | ENSSHAG00000004159 |
9823 | Sus scrofa | ENSSSCG00000011211 | 37347 | Tupaia belangeri | ENSTBEG00000004123 |
59729 | Taeniopygia guttata | ENSTGUG00000003349 | 99883 | Tetraodon nigroviridis | ENSTNIG00000003353 |
9478 | Tarsius syrichta | ENSTSYG00000008478 | 9739 | Tursiops truncatus | ENSTTRG00000001859 |
30538 | Vicugna pacos | ENSVPAG00000005832 | 8364 | Xenopus tropicalis | ENSXETG00000024399 |
59463 | Myotis lucifugus | ENSMLUG00000009632 | 9669 | Mustela putorius furo | ENSMPUG00000014923 |
7757 | Petromyzon marinus | ENSPMAG00000005715 |