Basic Information
Gene ID 19013 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Ppara; Nr1c1, Ppar
Full Name Peroxisome proliferator-activated receptor alpha
Organism Mus musculus [10090]

Cross Reference
UniProt P23204 UniGene Mm.212789
PDB NULL OMIM NULL
KEGG mmu:19013 UCSC uc007xdj.2

Protein Interactions
DIP DIP-5958N
IntAct P23204
MINT NULL
STRING 10090.ENSMUSP00000059719

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000105049 Gene3D G3DSA:1.10.565.10 IPR008946 155 185 7.60e-70 Nuclear hormone receptor, ligand-binding
ENSMUSP00000105049 Gene3D G3DSA:1.10.565.10 IPR008946 242 465 7.60e-70 Nuclear hormone receptor, ligand-binding
ENSMUSP00000105049 Gene3D G3DSA:3.30.50.10 IPR013088 102 154 5.90e-25 Zinc finger, NHR/GATA-type
ENSMUSP00000105049 Pfam PF00104 IPR000536 274 447 4.60e-24 Nuclear hormone receptor, ligand-binding, core
ENSMUSP00000105049 Pfam PF00105 IPR001628 101 167 5.40e-28 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 PRINTS PR00047 IPR001628 102 118 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 PRINTS PR00047 IPR001628 118 133 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 PRINTS PR00047 IPR001628 150 158 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 PRINTS PR00047 IPR001628 158 166 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 PRINTS PR00398 IPR001723 162 172 5.30e-26 Steroid hormone receptor
ENSMUSP00000105049 PRINTS PR00398 IPR001723 279 300 5.30e-26 Steroid hormone receptor
ENSMUSP00000105049 PRINTS PR00398 IPR001723 300 316 5.30e-26 Steroid hormone receptor
ENSMUSP00000105049 PRINTS PR00398 IPR001723 368 383 5.30e-26 Steroid hormone receptor
ENSMUSP00000105049 PRINTS PR00398 IPR001723 425 442 5.30e-26 Steroid hormone receptor
ENSMUSP00000105049 PRINTS PR01288 IPR003074 192 206 2.50e-53 Peroxisome proliferator-activated receptor
ENSMUSP00000105049 PRINTS PR01288 IPR003074 206 225 2.50e-53 Peroxisome proliferator-activated receptor
ENSMUSP00000105049 PRINTS PR01288 IPR003074 318 331 2.50e-53 Peroxisome proliferator-activated receptor
ENSMUSP00000105049 PRINTS PR01288 IPR003074 335 350 2.50e-53 Peroxisome proliferator-activated receptor
ENSMUSP00000105049 PRINTS PR01288 IPR003074 353 366 2.50e-53 Peroxisome proliferator-activated receptor
ENSMUSP00000105049 PRINTS PR01288 IPR003074 415 432 2.50e-53 Peroxisome proliferator-activated receptor
ENSMUSP00000105049 PRINTS PR01288 IPR003074 449 461 2.50e-53 Peroxisome proliferator-activated receptor
ENSMUSP00000105049 PRINTS PR01289 IPR003076 245 262 7.80e-72 Peroxisome proliferator-activated receptor, alpha
ENSMUSP00000105049 PRINTS PR01289 IPR003076 28 49 7.80e-72 Peroxisome proliferator-activated receptor, alpha
ENSMUSP00000105049 PRINTS PR01289 IPR003076 397 414 7.80e-72 Peroxisome proliferator-activated receptor, alpha
ENSMUSP00000105049 PRINTS PR01289 IPR003076 49 70 7.80e-72 Peroxisome proliferator-activated receptor, alpha
ENSMUSP00000105049 PRINTS PR01289 IPR003076 72 89 7.80e-72 Peroxisome proliferator-activated receptor, alpha
ENSMUSP00000105049 PRINTS PR01289 IPR003076 9 27 7.80e-72 Peroxisome proliferator-activated receptor, alpha
ENSMUSP00000105049 ProSitePatterns PS00031 IPR001628 102 128 - Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 ProSiteProfiles PS51030 IPR001628 99 173 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 SMART SM00399 IPR001628 99 169 7.40e-37 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000105049 SMART SM00430 IPR000536 278 437 8.90e-28 Nuclear hormone receptor, ligand-binding, core
ENSMUSP00000105049 SUPERFAMILY SSF48508 IPR008946 204 467 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000105049 PF00105 2.6e-28 zf-C4 Zinc finger, C4 type (two domains)
ENSMUSP00000105049 PF00104 2.4e-24 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000105049 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSMUSP00000105049 GO:0030522 biological_process intracellular receptor signaling pathway
ENSMUSP00000105049 GO:0042060 biological_process wound healing
ENSMUSP00000105049 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMUSP00000105049 GO:0005634 cellular_component nucleus
ENSMUSP00000105049 GO:0003677 molecular_function DNA binding
ENSMUSP00000105049 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000105049 GO:0003707 molecular_function steroid hormone receptor activity
ENSMUSP00000105049 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSMUSP00000105049 GO:0008144 molecular_function drug binding
ENSMUSP00000105049 GO:0008270 molecular_function zinc ion binding
ENSMUSP00000105049 GO:0008289 molecular_function lipid binding
ENSMUSP00000105049 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100166941 9483 Callithrix jacchus 100415661
61853 Nomascus leucogenys 100602258 9785 Loxodonta africana 100657770
8128 Oreochromis niloticus 100709869 10029 Cricetulus griseus 100758990
9597 Pan paniscus 100975411 9555 Papio anubis 101011461
39432 Saimiri boliviensis 101032215 9595 Gorilla gorilla 101146658
9669 Mustela putorius furo 101671312 43179 Ictidomys tridecemlineatus 101960603
8083 Xiphophorus maculatus 102236028 7897 Latimeria chalumnae 102352650
10116 Rattus norvegicus 25747 7955 Danio rerio 557714
7668 Strongylocentrotus purpuratus 576339 9544 Macaca mulatta 613250
9358 Choloepus hoffmanni ENSCHOG00000003604 9361 Dasypus novemcinctus ENSDNOG00000009243
10020 Dipodomys ordii ENSDORG00000003547 9796 Equus caballus ENSECAG00000000484
9371 Echinops telfairi ENSETEG00000013610 9685 Felis catus ENSFCAG00000005547
69293 Gasterosteus aculeatus ENSGACG00000003703 9031 Gallus gallus ENSGALG00000022985
8049 Gadus morhua ENSGMOG00000001060 9315 Macropus eugenii ENSMEUG00000003456
9103 Meleagris gallopavo ENSMGAG00000013838 30608 Microcebus murinus ENSMICG00000016757
13616 Monodelphis domestica ENSMODG00000007365 9258 Ornithorhynchus anatinus ENSOANG00000006277
9986 Oryctolagus cuniculus ENSOCUG00000009353 30611 Otolemur garnettii ENSOGAG00000004830
8090 Oryzias latipes ENSORLG00000002413 9601 Pongo abelii ENSPPYG00000011942
13735 Pelodiscus sinensis ENSPSIG00000018221 132908 Pteropus vampyrus ENSPVAG00000010498
9305 Sarcophilus harrisii ENSSHAG00000002812 9823 Sus scrofa ENSSSCG00000000006
37347 Tupaia belangeri ENSTBEG00000017305 59729 Taeniopygia guttata ENSTGUG00000011797
99883 Tetraodon nigroviridis ENSTNIG00000006254 9478 Tarsius syrichta ENSTSYG00000007368
9739 Tursiops truncatus ENSTTRG00000004136 9646 Ailuropoda melanoleuca ENSAMEG00000003383
31033 Takifugu rubripes ENSTRUG00000016463