Basic Information
Gene ID 557714
Gene Name pparab
Full Name Peroxisome proliferator activated receptor alpha
Organism Danio rerio [7955]

Cross Reference
UniProt A6XMH7 UniGene Dr.103116
PDB NULL OMIM NULL
KEGG dre:557714 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000126384 Gene3D G3DSA:1.10.565.10 IPR008946 150 180 1.30e-72 Nuclear hormone receptor, ligand-binding
ENSDARP00000126384 Gene3D G3DSA:1.10.565.10 IPR008946 232 456 1.30e-72 Nuclear hormone receptor, ligand-binding
ENSDARP00000126384 Gene3D G3DSA:3.30.50.10 IPR013088 97 149 5.20e-25 Zinc finger, NHR/GATA-type
ENSDARP00000126384 Pfam PF00104 IPR000536 270 434 9.10e-30 Nuclear hormone receptor, ligand-binding, core
ENSDARP00000126384 Pfam PF00105 IPR001628 96 162 4.70e-28 Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 PRINTS PR00047 IPR001628 113 128 1.30e-18 Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 PRINTS PR00047 IPR001628 145 153 1.30e-18 Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 PRINTS PR00047 IPR001628 153 161 1.30e-18 Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 PRINTS PR00047 IPR001628 97 113 1.30e-18 Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 PRINTS PR00398 IPR001723 157 167 1.90e-26 Steroid hormone receptor
ENSDARP00000126384 PRINTS PR00398 IPR001723 271 292 1.90e-26 Steroid hormone receptor
ENSDARP00000126384 PRINTS PR00398 IPR001723 292 308 1.90e-26 Steroid hormone receptor
ENSDARP00000126384 PRINTS PR00398 IPR001723 360 375 1.90e-26 Steroid hormone receptor
ENSDARP00000126384 PRINTS PR00398 IPR001723 417 434 1.90e-26 Steroid hormone receptor
ENSDARP00000126384 PRINTS PR01288 IPR003074 197 216 3.00e-44 Peroxisome proliferator-activated receptor
ENSDARP00000126384 PRINTS PR01288 IPR003074 310 323 3.00e-44 Peroxisome proliferator-activated receptor
ENSDARP00000126384 PRINTS PR01288 IPR003074 327 342 3.00e-44 Peroxisome proliferator-activated receptor
ENSDARP00000126384 PRINTS PR01288 IPR003074 345 358 3.00e-44 Peroxisome proliferator-activated receptor
ENSDARP00000126384 PRINTS PR01288 IPR003074 407 424 3.00e-44 Peroxisome proliferator-activated receptor
ENSDARP00000126384 PRINTS PR01288 IPR003074 440 452 3.00e-44 Peroxisome proliferator-activated receptor
ENSDARP00000126384 PRINTS PR01289 IPR003076 235 252 8.60e-17 Peroxisome proliferator-activated receptor, alpha
ENSDARP00000126384 PRINTS PR01289 IPR003076 25 46 8.60e-17 Peroxisome proliferator-activated receptor, alpha
ENSDARP00000126384 PRINTS PR01289 IPR003076 389 406 8.60e-17 Peroxisome proliferator-activated receptor, alpha
ENSDARP00000126384 PRINTS PR01289 IPR003076 68 85 8.60e-17 Peroxisome proliferator-activated receptor, alpha
ENSDARP00000126384 ProSitePatterns PS00031 IPR001628 97 123 - Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 ProSiteProfiles PS51030 IPR001628 94 168 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 SMART SM00399 IPR001628 94 164 1.70e-36 Zinc finger, nuclear hormone receptor-type
ENSDARP00000126384 SMART SM00430 IPR000536 270 429 1.60e-32 Nuclear hormone receptor, ligand-binding, core
ENSDARP00000126384 SUPERFAMILY SSF48508 IPR008946 195 458 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000126384 PF00104 5e-30 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSDARP00000126384 PF00105 2.4e-28 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000126384 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSDARP00000126384 GO:0030522 biological_process intracellular receptor signaling pathway
ENSDARP00000126384 GO:0042060 biological_process wound healing
ENSDARP00000126384 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSDARP00000126384 GO:0005634 cellular_component nucleus
ENSDARP00000126384 GO:0003677 molecular_function DNA binding
ENSDARP00000126384 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSDARP00000126384 GO:0003707 molecular_function steroid hormone receptor activity
ENSDARP00000126384 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSDARP00000126384 GO:0008144 molecular_function drug binding
ENSDARP00000126384 GO:0008270 molecular_function zinc ion binding
ENSDARP00000126384 GO:0008289 molecular_function lipid binding
ENSDARP00000126384 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100415661 9785 Loxodonta africana 100657770
9555 Papio anubis 101011461 9595 Gorilla gorilla 101146658
7897 Latimeria chalumnae 102352650 10090 Mus musculus 19013
10116 Rattus norvegicus 25747 9598 Pan troglodytes 463188
61853 Nomascus leucogenys 100602258 8128 Oreochromis niloticus 100709869
10029 Cricetulus griseus 100758990 7463 Apis florea 100870379
9597 Pan paniscus 100975411 39432 Saimiri boliviensis 101032215
9669 Mustela putorius furo 101671312 43179 Ictidomys tridecemlineatus 101960603
8083 Xiphophorus maculatus 102236028 9913 Bos taurus 353106
10020 Dipodomys ordii ENSDORG00000003547 9371 Echinops telfairi ENSETEG00000013610
9031 Gallus gallus ENSGALG00000022985 9103 Meleagris gallopavo ENSMGAG00000013838
13616 Monodelphis domestica ENSMODG00000007365 9258 Ornithorhynchus anatinus ENSOANG00000006277
9986 Oryctolagus cuniculus ENSOCUG00000009353 30611 Otolemur garnettii ENSOGAG00000004830
9823 Sus scrofa ENSSSCG00000000006 37347 Tupaia belangeri ENSTBEG00000017305
59729 Taeniopygia guttata ENSTGUG00000011797 99883 Tetraodon nigroviridis ENSTNIG00000006254
9739 Tursiops truncatus ENSTTRG00000004136 9544 Macaca mulatta 613250
9646 Ailuropoda melanoleuca ENSAMEG00000003383 9361 Dasypus novemcinctus ENSDNOG00000009243
9796 Equus caballus ENSECAG00000000484 9685 Felis catus ENSFCAG00000005547
69293 Gasterosteus aculeatus ENSGACG00000003703 7757 Petromyzon marinus ENSPMAG00000008839
9601 Pongo abelii ENSPPYG00000011942 13735 Pelodiscus sinensis ENSPSIG00000018221
132908 Pteropus vampyrus ENSPVAG00000010498 9305 Sarcophilus harrisii ENSSHAG00000002812
31033 Takifugu rubripes ENSTRUG00000016463

Paralogs
ENSDARG00000091024