Basic Information
Gene ID 613250
Gene Name PPARA
Full Name Peroxisome proliferator activated receptor
Organism Macaca mulatta [9544]

Cross Reference
UniProt Q4PNY3 UniGene Mmu.4695
PDB NULL OMIM NULL
KEGG mcc:613250 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9544.ENSMMUP00000021366

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMMUP00000021366 Gene3D G3DSA:1.10.565.10 IPR008946 155 185 3.40e-71 Nuclear hormone receptor, ligand-binding
ENSMMUP00000021366 Gene3D G3DSA:1.10.565.10 IPR008946 242 464 3.40e-71 Nuclear hormone receptor, ligand-binding
ENSMMUP00000021366 Gene3D G3DSA:3.30.50.10 IPR013088 102 154 5.90e-25 Zinc finger, NHR/GATA-type
ENSMMUP00000021366 Pfam PF00104 IPR000536 278 448 6.50e-25 Nuclear hormone receptor, ligand-binding, core
ENSMMUP00000021366 Pfam PF00105 IPR001628 101 167 5.30e-28 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 PRINTS PR00047 IPR001628 102 118 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 PRINTS PR00047 IPR001628 118 133 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 PRINTS PR00047 IPR001628 150 158 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 PRINTS PR00047 IPR001628 158 166 8.00e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 PRINTS PR00398 IPR001723 162 172 7.80e-26 Steroid hormone receptor
ENSMMUP00000021366 PRINTS PR00398 IPR001723 279 300 7.80e-26 Steroid hormone receptor
ENSMMUP00000021366 PRINTS PR00398 IPR001723 300 316 7.80e-26 Steroid hormone receptor
ENSMMUP00000021366 PRINTS PR00398 IPR001723 368 383 7.80e-26 Steroid hormone receptor
ENSMMUP00000021366 PRINTS PR00398 IPR001723 425 442 7.80e-26 Steroid hormone receptor
ENSMMUP00000021366 PRINTS PR01288 IPR003074 192 206 1.70e-53 Peroxisome proliferator-activated receptor
ENSMMUP00000021366 PRINTS PR01288 IPR003074 206 225 1.70e-53 Peroxisome proliferator-activated receptor
ENSMMUP00000021366 PRINTS PR01288 IPR003074 318 331 1.70e-53 Peroxisome proliferator-activated receptor
ENSMMUP00000021366 PRINTS PR01288 IPR003074 335 350 1.70e-53 Peroxisome proliferator-activated receptor
ENSMMUP00000021366 PRINTS PR01288 IPR003074 353 366 1.70e-53 Peroxisome proliferator-activated receptor
ENSMMUP00000021366 PRINTS PR01288 IPR003074 415 432 1.70e-53 Peroxisome proliferator-activated receptor
ENSMMUP00000021366 PRINTS PR01288 IPR003074 448 460 1.70e-53 Peroxisome proliferator-activated receptor
ENSMMUP00000021366 PRINTS PR01289 IPR003076 245 262 9.60e-71 Peroxisome proliferator-activated receptor, alpha
ENSMMUP00000021366 PRINTS PR01289 IPR003076 28 49 9.60e-71 Peroxisome proliferator-activated receptor, alpha
ENSMMUP00000021366 PRINTS PR01289 IPR003076 397 414 9.60e-71 Peroxisome proliferator-activated receptor, alpha
ENSMMUP00000021366 PRINTS PR01289 IPR003076 49 70 9.60e-71 Peroxisome proliferator-activated receptor, alpha
ENSMMUP00000021366 PRINTS PR01289 IPR003076 72 89 9.60e-71 Peroxisome proliferator-activated receptor, alpha
ENSMMUP00000021366 PRINTS PR01289 IPR003076 9 27 9.60e-71 Peroxisome proliferator-activated receptor, alpha
ENSMMUP00000021366 ProSitePatterns PS00031 IPR001628 102 128 - Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 ProSiteProfiles PS51030 IPR001628 99 173 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 SMART SM00399 IPR001628 99 169 7.40e-37 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000021366 SMART SM00430 IPR000536 278 437 3.80e-28 Nuclear hormone receptor, ligand-binding, core
ENSMMUP00000021366 SUPERFAMILY SSF48508 IPR008946 204 466 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMMUP00000021366 PF00105 2.7e-28 zf-C4 Zinc finger, C4 type (two domains)
ENSMMUP00000021366 PF00104 3.5e-25 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMMUP00000021366 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSMMUP00000021366 GO:0030522 biological_process intracellular receptor signaling pathway
ENSMMUP00000021366 GO:0042060 biological_process wound healing
ENSMMUP00000021366 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMMUP00000021366 GO:0005634 cellular_component nucleus
ENSMMUP00000021366 GO:0003677 molecular_function DNA binding
ENSMMUP00000021366 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMMUP00000021366 GO:0003707 molecular_function steroid hormone receptor activity
ENSMMUP00000021366 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSMMUP00000021366 GO:0008144 molecular_function drug binding
ENSMMUP00000021366 GO:0008270 molecular_function zinc ion binding
ENSMMUP00000021366 GO:0008289 molecular_function lipid binding
ENSMMUP00000021366 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100415661 9555 Papio anubis 101011461
9595 Gorilla gorilla 101146658 10090 Mus musculus 19013
7668 Strongylocentrotus purpuratus 576339 7029 Acyrthosiphon pisum 100166941
61853 Nomascus leucogenys 100602258 30195 Bombus terrestris 100644185
9785 Loxodonta africana 100657770 8128 Oreochromis niloticus 100709869
132113 Bombus impatiens 100744917 10029 Cricetulus griseus 100758990
143995 Megachile rotundata 100876784 34638 Metaseiulus occidentalis 100899165
9597 Pan paniscus 100975411 39432 Saimiri boliviensis 101032215
9669 Mustela putorius furo 101671312 43179 Ictidomys tridecemlineatus 101960603
8083 Xiphophorus maculatus 102236028 7897 Latimeria chalumnae 102352650
10116 Rattus norvegicus 25747 7227 Drosophila melanogaster 39999
7460 Apis mellifera 410309 7955 Danio rerio 557714
7070 Tribolium castaneum 660005 9358 Choloepus hoffmanni ENSCHOG00000003604
10020 Dipodomys ordii ENSDORG00000003547 9371 Echinops telfairi ENSETEG00000013610
9685 Felis catus ENSFCAG00000005547 69293 Gasterosteus aculeatus ENSGACG00000003703
9031 Gallus gallus ENSGALG00000022985 8049 Gadus morhua ENSGMOG00000001060
9315 Macropus eugenii ENSMEUG00000003456 9103 Meleagris gallopavo ENSMGAG00000013838
30608 Microcebus murinus ENSMICG00000016757 13616 Monodelphis domestica ENSMODG00000007365
9258 Ornithorhynchus anatinus ENSOANG00000006277 9986 Oryctolagus cuniculus ENSOCUG00000009353
30611 Otolemur garnettii ENSOGAG00000004830 8090 Oryzias latipes ENSORLG00000002413
13735 Pelodiscus sinensis ENSPSIG00000018221 9823 Sus scrofa ENSSSCG00000000006
37347 Tupaia belangeri ENSTBEG00000017305 59729 Taeniopygia guttata ENSTGUG00000011797
99883 Tetraodon nigroviridis ENSTNIG00000006254 9478 Tarsius syrichta ENSTSYG00000007368
9739 Tursiops truncatus ENSTTRG00000004136 9646 Ailuropoda melanoleuca ENSAMEG00000003383
9361 Dasypus novemcinctus ENSDNOG00000009243 9796 Equus caballus ENSECAG00000000484
7757 Petromyzon marinus ENSPMAG00000008839 9601 Pongo abelii ENSPPYG00000011942
132908 Pteropus vampyrus ENSPVAG00000010498 9305 Sarcophilus harrisii ENSSHAG00000002812
31033 Takifugu rubripes ENSTRUG00000016463