Not logged in
  • Log in
    Membership (40250+) Group hosting [?] Wiki
    Franklin Award

    About bioinformatics
    Bioinformatics training
    Bioinformatics jobs

    All information groups
    Online databases Online analysis tools Online education tools More tools

    All software groups
    FTP repository
    SVN & CVS repositories [?]
    Mailing lists

    News & Commentary
  • Submit
  • Archives
  • Subscribe

  • Jobs Forum
    (Career Center)
  • Submit
  • Archives
  • Subscribe
  • News & Commentary - Message forums

    URL: Prediction of Conformational Epitope online
    Submitted by shonna; posted on Friday, May 29, 2009

    Phage display technique is an established combinatorial technology to characterize conformational epitopes of proteins. It identifies the peptide epitopes (also known as mimotopes) by binding to monoclonal antibodies similar to the natural epitopes. In general the antibody recognizes a discontinuous fragment (conformational) of amino acid residues on the surface of an antigen. Therefore to locate the interaction site mimicked by the epitope on the antigen surface using just sequence alignment is not possible. A new and fully automated method "EpiSearch" has been developed to analyze and predict the conformational epitopes on the surface of an antigen. The algorithm uses input peptide sequences obtained from the phage display experiment and maps it on the monomer surface of an interacting antigen structure.


    Expanded view | Monitor forum | Save place

    Start a new thread:
    You have to be logged in to post a reply.


    Copyright © 2018 · Scilico, LLC