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    BACKGROUND

    A POSTDOC POSITION is available immediately in the lab of Dr. Jeffrey Chang (changlab.uth.tmc.edu) at the University of Texas Health Science Center at Houston in the field of cancer genomics. This position is part of a program to study triple negative breast cancer (TNBC) in the context of a clinical trial with MD Anderson Cancer Center, and is funded by the Cancer Prevention and Research Institute of Texas. The project will be to develop computational methods and pipelines to perform genomic analysis on TNBC samples, as well as to support experimental researchers as needed. The successful applicant will have experience in performing bioinformatic analysis of a range of data types (genome sequencing, RNA-seq, microarrays) to dissect the molecular determinants of the disease.

    REQUIREMENTS

    To join our group, we are looking for highly motivated individuals that have demonstrated scientific productivity, excellent communication skills, and the capacity to conduct independent research. We are interested in applicants with a Ph.D. in Bioinformatics, Computer Science, Statistics, or comparable experience. Experience with next generation sequencing is highly desired. A background in cancer biology is a plus. Salary will follow NIH and university guidelines.

    HOW TO APPLY

    Please send a CV, a brief statement of research interests, and contact information for three references to Dr. Jeffrey Chang (jeffrey.t.chang[at]uth.tmc.edu). IMPORTANT: please include the words "Cancer Genomics Postdoc" in the subject line of the email.

    POLICY

    UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, gender, sexual orientation, national origin, genetics, disability, age, or any other basis prohibited by law. EOE/M/D/F/V.

    BACKGROUND

    An exciting Software Analysis and Development opportunity has become available within the Cancer, Ageing and Somatic Mutation Group (CASM). The successful candidate will be embedded in a large multidisciplinary team and will be tasked with further developing our cancer analysis algorithms specifically for blood cancers. The role involves working closely with scientific and IT staff within CASM to develop novel analytical strategies as well as actively contributing to the statistical modelling and data analysis of this study. In addition, the role will also involve improving existing algorithms to analyse whole genome sequencing and methylation data as well as developing new software where required. The position would suit a Bioinformatician/Statistician who enjoys developing algorithms and building statistical models to analyse complex NGS biological datasets. We are looking for an individual who enjoys working in a multi-disciplinary team environment to help solve complex IT issues which will ultimately aid our analysis of cancer related datasets.

    RESPONSIBILITIES

    The role involves working closely with scientific and IT staff within CASM to develop novel analytical strategies as well as actively contributing to the statistical modelling and data analysis of this study. In addition, the role will also involve improving existing algorithms to analyse whole genome sequencing and methylation data as well as developing new software where required. The position would suit a Bioinformatician/Statistician who enjoys developing algorithms and building statistical models to analyse complex NGS biological datasets. We are looking for an individual who enjoys working in a multi-disciplinary team environment to help solve complex IT issues which will ultimately aid our analysis of cancer related datasets.

    REQUIREMENTS

    • Good degree in Bioinformatics, Mathematics, Statistics or Computer Science with a scientific background
    • Software development using a compiled language (C,C++, Java)
    • Software development skills (using Perl and/or Python)
    • Experience of statistical analysis in bioinformatics
    • Experience of analysing biological data
    • Extensive experience of communicating effectively internally at all levels and with select external individuals
    • Able to present data
    • Ability to work independently and organise own workload
    • Previous scientific publications
    • Enjoy working as part of a team

    PREFERENCES

    • PhD in a bioinformatics or mathematics subject
    • ORACLE/MySQL databases
    • LSF or Open Grid scheduling software
    • Experience of workflow management IT systems
    • Experience of VMware, OpenStack or Amazon Web Services (AWS)
    • Experience working, developing and compiling software tools in a UNIX/LINUX environment.
    • Background in cancer genetics
    • Evidence of academic excellence

    TERMS

    Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

    LOCALE

    The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society. To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

    COMPENSATION

    £31,498 to £39,729, plus excellent benefits.

    Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

    ABOUT US

    The CASM Group has led the way in the systematic analysis of cancer genomes by using the human genome sequence and high throughput mutation detection techniques to identify somatically acquired sequence variants/mutations and hence identify genes critical in the development of human cancers (www.sanger.ac.uk/genetics/CGP/). The IT group has developed a suite of algorithms to analyse genetic variation in cancer genome data. This includes software to detect tumour genetic variation (e.g. single-base substitutions, structural rearrangements, copy number changes) and the ability to annotate the resulting variants and mine the data for interesting patterns and signatures. Campus Life The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

    HOW TO APPLY

    Click on the following link: jobs.sanger.ac.uk/wd/p[...]04870

    Please include a covering letter and CV with your application.

    DEADLINE

    22nd March 2017

    Submitter

    BACKGROUND

    CSRA is seeking a full time Senior Bioinformatics Engineer to join our program in support of the National Cancer Institute (NCI). NCI runs multiple programs for cancer genomics, including TARGET, CTD2, CGCI, and HCMI. CSRA needs a Senior Bioinformatics Engineer to help as part of the Data Coordinating Center for these cancer research efforts. CSRA has a leading practice in bioinformatics supporting the Federal Government, with projects across the NIH and CDC.

    RESPONSIBILITIES

    • Work involves intake and formatting of genomics data via extensive scripting, transfer of data to NCI's Genomics Data Commons, development and maintenance of web applications, coordination with NIH's Center for Information Technology regarding security, storage space, and web hosting.
    • This is an opportunity to make a difference on the cutting edge of cancer research, using bioinformatics skills that require a knowledge of genomics and molecular biology as well as significant IT skills, working with some of the top cancer researchers in the world.
    • The selected candidate will have had extensive experience with handling, manipulating, and performing QC on genomics data, including WGS, WES, and RNASeq data.

    REQUIREMENTS

    Required skills:
    • Bachelors degree and 5+ years hands on bioinformatics experience is required, or equivalent combination. MS preferred
    • Advanced Linux, Perl, and Apache skills (additional skills in Python are a preferred)
    • Extensive knowledge of genomics metadata and data standards
    • Demonstrated expertise creating and maintaining bioinformatics workflows
    • Web application maintenance
    • Experiencing completing setup, managing, and maintaining servers, storage, application stacks, tools, security, code management beyond basic systems support
    • Experience with biomedical data migration and QC
    • Extensive experience in managing genomics data via hands-on programming experience
    Competencies:
    • Excellent verbal and written communication skills required
    • Ability to multi-task in a fast paced environment

    PREFERENCES

    Desired skills:
    • Java
    • Knowledge of dbGaP, SRA, NCI Genomic Data Commons preferred
    • Experience with components of the NCI multi-tier development and deployment stack (Java, Tomcat, AntHillPro, Maven, GitHub)
    • Cancer-specific genomics/bioinformatics experience preferred

    LOCALE

    Onsite at the NCI in Rockville, MD

    HOW TO APPLY

    Please apply directly online via www.csra.com/careers to job #13045 or via this link: jobs.csra.com/sear[...]983/1

    POLICY

    CSRA is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

    BACKGROUND

    Zymeworks is a fast-growing, clinical-stage biotechnology company dedicated to the research, development and commercialization of best-in-class therapeutic bispecific antibodies and antibody drug conjugates used in the treatment of cancer and autoimmune diseases. Zymeworks is proud to have active collaborations with Merck & Co., Inc., Eli Lilly and Co., Celgene Corporation and GSK, and is committed to making a meaningful difference in the lives of patients everywhere.

    Zymeworks is seeking a LIMS/ELN Informatics Analyst, who will be responsible for modeling experimental workflows, as well as managing and maintaining quality control of experimental and biological data in a Laboratory Information Management System (LIMS) and Electronic Lab Notebook (ELN). The position reports to the Technology Integration & Bioinformatics Team Lead.

    RESPONSIBILITIES

    • Interfaces with our scientific R&D teams to understand the experimental data being produced, provides proposals to organize and formalize the data from these experiments, and works with the software team to store this data in the LIMS/ELN
    • Manages and organizes the storage of our biological data (protein products, antibodies, small molecules, other molecular entities) in the LIMS/ELN, along with associated metadata
    • Administers the LIMS/ELN by assigning roles and permissions to the various groups and users in the organization
    • Works with our in-house lab scientists, and external Contract Research Organizations to develop, document, and enforce standard operating procedures and protocols for our experiments and the associated data upload and management procedures
    • Acts as a point of contact for LIMS/ELN-associated feature requests and work with the users and various stakeholders on prioritizing and delivering these features
    • Works with the LIMS provider and in-house scientific and software teams to implement and support best practices and optimal utilization of the informatics and data management resources
    • Documents and trains scientific staff/end user on best practices and compliance policies related to the LIMS/ELN system and data handling
    Fosters effective and collaborative working relationships with fellow employees, management and external partners

    REQUIREMENTS

    • BSc in Biochemistry, Molecular Biology, Chemistry or a related field and a minimum of 2 years' experience working with LIMS/ELN software in the biopharmaceutical industry
    • Proven interpersonal skills with the ability to work collaboratively as a member of cross-functional team. Ability to establish and maintain effective working relationships
    • Familiarity with proteins, protein expression and purification methods is required, as well as basic knowledge of experiments like mass spectroscopy, DSC, SPR, FACS or other cell-based assays is required.
    • Should be IT savvy, experience and strong drive to work in data management including capturing, refining, annotating, characterizing, and storing data is a must.
    • Experience in the capture and management of high throughput experimental data will be an asset.
    • Experience in negotiating software requirements within and across research departments and translate those requirements to software solutions
    • Basic experience with any programming languages (Python, C/C++, Fortran, Java), or experience with scripting languages like Bash/Perl is an asset. Basic knowledge of databases like SQL, PostgreSQL will be highly favored.
    • Fluent in written and spoken English

    ABOUT US

    Why Work for Us?

    Zymeworks' employees are passionate, engaged and extremely motivated to succeed. We are excited by the cutting-edge science and technology, the endless possibilities this union holds and the sheer opportunity to be a part of something big. To learn more about Zymeworks Inc. and our current openings, please visit our website at www.zymeworks.com.

    We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.

    HOW TO APPLY

    If you are interested in applying for this position, please email your curriculum vitae and cover letter including available start date in PDF format with "1401 – LIMS/ELN Informatics Analyst" in the subject line to zymeworks-job80[at]mytribehr.com. Due to the high volume of applicants, only those selected for interviews will be contacted.

    RESPONSIBILITIES

    We seek a talented computational scientist to specialize in analysis and interpretation of high-throughput epigenomic data to elucidate key aspects of therapeutic action. The insight gained will contribute directly to identification and development of novel therapies for complex diseases of unmet medical need.

    The successful candidate will work closely with Celgene's global research analytics and epigenetic biology teams to advance our research and development of novel therapeutic agents related to epigenetic mechanisms. The role will involve participation in the analysis and interpretation of experiments that capitalize on cancer therapeutic opportunities in epigenetics.

    A key area of research focus will be the integration of multiple genomic data types to produce a robust understanding of disease state or phenotype. In the context of therapeutic discovery, these efforts will yield novel high-confidence drug targets, and in the context of translational research, objectives include understanding mechanisms of response to our emerging therapeutics.

    Research Analytics activities at CITRE focus on application of contemporary computational analysis methods to improve therapeutic outcomes for Celgene patient populations across a range of diseases. This position would involve considerable inter-disciplinary collaboration with colleagues across Celgene Research and academic collaborators.

    The successful candidate for this role will work closely with Research Analytics team members to define and execute projects, and to communicate discoveries to biology and clinical research teams.

    Responsibilities include, but are not limited to:
    • Perform computational biology analysis for exploration and interpretation of high-throughput data including NGS and MS proteomics assays
    • Develop and implement state-of-the-art approaches for biological pathway and network analysis to elucidate the perturbation of cellular mechanisms
    • Engage in development of methods and platforms for integration of heterogeneous biological data towards answering broader scientific questions
    • Participate in the presentation and reporting of methods, results and conclusions to a publishable standard
    • Participate in wider group endeavors concerning the elucidation of compound mechanisms of action, drug resistance and prediction of target indications

    REQUIREMENTS

    • PhD in computational biology / bioinformatics, statistics, computer science or related fields, with a firm grasp of genomics and/or genetics, from a recognized higher-education establishment
    • Post-doctoral research experience (2+ years) preferred in analysis, integration and interpretation of epigenomic and other high-throughput data (e.g. Histone & TF ChIP, DNA methylation, chromatin accessibility, proteomics and expression data)
    • Publication record in analysis of next-generation sequencing data: familiarity with publicly-available sequence alignment pipelines, SNV calling algorithms, common NGS manipulation tools and standardized NGS data formats (e.g. SAM/BAM, VCF)
    • Demonstrable competence in statistical programming and data manipulation, using e.g. Unix/Linux, Perl, Python, and R/Matlab/SAS, plus good knowledge of contemporary database structures
    • Familiarity with protein interaction/regulatory network collections and network/pathway based analysis methods to distil rational biological interpretation and functional insight from biological data
    • Ability to collaborate well and communicate the output of computational research in the context of multi-disciplinary scientific teams
    • Excellent oral and written communication skills in English. Proficiency in Spanish language would be advantageous

    LOCALE

    CITRE, Seville, Spain

    TERMS

    Manager: Principal Scientist, Research Analytics (RIKU)
    Contract: Fixed-term, 2 year duration, full-time

    ABOUT US

    CITRE Background:
    Multinational biopharmaceutical company Celgene, world leader in developing new treatments for cancer and inflammatory diseases, has established the Celgene Institute for Translational Research Europe (CITRE®) in Seville, Spain. CITRE is the company's first dedicated R&D site outside the USA and provides a bridge between Celgene R&D and the European research community.

    CITRE was founded in 2010, and laboratory research activities began in June 2011. The Institute now houses a team of highly qualified scientific research and administrative staff drawn from Spain and other European member states. The Institute is located in the Cartuja `93 Science and Technology Park and its activities focus on Translational Research into new treatments for cancer and other rare and complex diseases.

    Scientific activities at CITRE comprise three main departments: The Human Diseased Tissue Laboratory (HDTL), the Computational Biology research group, and the Clinical Trials Unit. Onsite facilities include extensive cell culture, flow cytometry, microscopy, genomics, immunohistochemistry, and state-of-the-art computational analysis infrastructure for biomarker discovery and patient stratification.

    The three groups are inter-linked by the CITRE tissue Biobank, which receives patient tissue samples, obtained from multi-centre Celgene trials managed by the CITRE Clinical Trials Unit in Spain and across Europe, to provide the basis for inter-disciplinary research into biomarker detection, patient selection criteria, and compound mechanisms of action.

    Together, these components form a Translational Research centre which coordinates and conducts Celgene medical research in Europe, and enables rapid and effective transfer of new developments and discoveries at Celgene to EU patients. Furthermore, CITRE provides a focal point in Europe for collaborative translational research into cancer and inflammatory diseases, with a mission to rapidly deliver new Celgene compounds to the clinic.

    HOW TO APPLY

    Contact:
    Those interested in the position described should submit full CV and cover letter addressed to:
    Silvia Banus (sbanus[at]celgene.com)
    CELGENE S.L.
    Paseo de Recoletos 39, 4º
    28004 MADRID

    By sending your application you acknowledge that the information you provide to Celgene will be stored in a database which is the property of Celgene, for the purposes of processing this information. This information may be shared with Celgene affiliates and agents, including Celgene's parent company based in the USA (Celgene Corporation). You understand that you have the right of access to and the right to rectify the data concerning me, according to applicable privacy laws. You understand that these rights can be exercised by sending an email to the following address: privacy[at]celgene.com, and that more information can be found on the privacy policy located on Celgene's web site, www.celgene.com/util[...].aspx.

    BACKGROUND

    Applications are sought for a Software Developer to maintain and enhance SNPnexus (www.snp-nexus.org) a hugely popular analytical tool that allows researchers to assess the potential significance of sequence variations that could lead to diseases. The successful candidate will be responsible for SNPnexus enhancement to ensure that it remains a cutting-edge tool and continues to contribute to maximising the knowledge extracted from sequencing data. The aim is to introduce new modules for multi-sample analyses, noncoding annotation and the discovery of novel/rare disease-causing variants, and improve its speed/efficacy. The post will be based in the Bioinformatics Unit, Centre of Molecular Oncology, Barts Cancer Institute, within the Barts and The London School of Medicine and Dentistry, Queen Mary University of London.

    REQUIREMENTS

    Essential requirements for this post include an MSc in Bioinformatics/Computer Science or a related discipline, significant experience in software development ideally in a life science environment. Experience in biological science research and familiarity with functional annotation of genome sequence variations are very desirable, and will be an advantage. A demonstrated ability to communicate well, work within a team are essential. The technical requirements for this post include expertise in CGI scripting language (e.g., Perl or Python), relational database management systems (e.g., MySQL), and web application development technologies. Experience of additional languages, such as C/C++ or Java, is also important. Experience with Linux network/server administration would be essential. Experience in R statistical environment and Bioconductor is desirable.

    TERMS

    The post is full time for 35 months, in the first instance.

    LOCALE

    Department: Centre for Molecular Oncology, Barts Cancer Institute
    Poplar, Greater London
    UK

    COMPENSATION

    Starting salary will be in the range £32,405 - £38,062 (Grade 4) per annum inclusive of London Allowance. Benefits include 30 days' annual leave, defined benefit pension scheme and interest-free season ticket loan.

    The Barts Cancer Institute requires that applicants invited for interview will need to provide all certificates to confirm their qualifications (specified in the Job Description).

    Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.

    HOW TO APPLY

    Informal enquiries about this post, including arrangements to visit the Institute/Centre, can be made to Professor Claude Chelala (c.chelala[at]qmul.ac.uk).

    Application enquiries can be directed to recruitment[at]qmul.ac.uk

    Details about Barts Cancer Institute can be found at www.bci.qmul.ac.uk

    To apply, please visit webapps2.is.qmul.ac.uk/jobs[...]10633

    Reference: QMUL10633

    Date posted: 23-Jan-2017

    DEADLINE

    The closing date is 26th February and interviews are likely to be held shortly thereafter.

    POLICY

    Valuing Diversity & Committed to Equality

    BACKGROUND

    Postdoctoral positions(both computational and wet lab) are available in the department of Bioinformatics and Computational Biology at the University of Texas MD Anderson Cancer Center (MDACC). We study resistance to targeted therapies and aim to discover combination therapies to overcome or forestall the resistance in cancer. Our laboratory combines advanced network inference and machine learning algorithms with drug perturbation and profiling experiments.

    Apply for a postdoc position If you are interested in
    • Working in a highly collaborative, experimental, computational and translational cancer biology program
    • Working at MDACC (ranked number one in the nation for cancer care by U.S. News & World Report and number one in the number of awarded grants from the NCI)
    • Having excellent benefits & salary

    REQUIREMENTS

    Computational: Candidates must have a PhD in a relevant field (e.g., bioinformatics, biophysics, genomics, computer science, statistics) and a strong track record. A good understanding of statistics, experience in algorithm development and programming skills (e.g., R, Matlab, C++, Fortran, Python) are required. Knowledge of cancer biology, signaling pathways and drug response mechanisms is highly preferred.

    Experimental: Candidates must have a PhD in a relevant field (e.g., cell biology, pharmacology, systems biology, biochemistry) and a strong track record. Experience in mammalian cell culture and drug perturbation experiments is required. Candidates must have the desire to gain experience in bioinformatics, very good quantitative skills, and statistics knowledge. For all candidates, a good understanding of cancer biology, signaling pathways and drug response mechanisms is highly preferred.

    LOCALE

    UT MD Anderson Cancer Center, Houston TX

    COMPENSATION

    $65K/yr for computational biology postdocs and NIH scale for experimentalist postdocs.

    ABOUT US

    MDACC is one of the world's foremost institutions for cancer research. It offers salaries and benefits that are highly competitive, especially given the relatively low cost of living in Houston. Houston is one of the world's most interesting and diverse cities, featuring great neighborhoods, excellent private and public schools, superb museums, highly acclaimed opera, symphony, ballet, and theater, first-rate international cuisine, and year-round recreational and entertainment opportunities.

    HOW TO APPLY

    Email letter of interest, CV, a list of 2-3 references to akorkut/at/mdanderson(dot)org. In your email, please make sure that subject line is "postdoc application/korkut lab".

    Contact:
    Anil Korkut
    Bioinformatics and Computational Biology
    The University of Texas M. D. Anderson Cancer Center
    1515 Holcombe Blvd.
    Houston, TX 77030
    United States
    Email: akorkut/at/mdanderson(dot)org

    POLICY

    M. D. Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.

    BACKGROUND

    About BSC:
    The Barcelona Supercomputing Center – Centro Nacional de Supercomputación (BSC-CNS) is the leading supercomputing center in Spain. It houses MareNostrum, one of the most powerful supercomputers in Europe, and is a hosting member of the PRACE European distributed supercomputing infrastructure. The mission of BSC is to research, develop and manage information technologies in order to facilitate scientific progress. BSC combines HPC service provision and R&D into both computer and computational science (life, earth and engineering sciences) under one roof, and currently has over 460 staff from 44 countries.

    RESPONSIBILITIES

    Context and Mission:
    Within the Life Sciences Department, we are looking for a Laboratory Manager. Under the Department Direction, the Lab Manager is responsible for the day-to-day operations of the department. The selected candidate will take responsibility to provide scientific and administrative guidance in relation to lab management, in accordance with established lab policies and practices and in conjunction with the department identified goals.

    Key Duties:
    • Establishes quality standards, supervises quality control, inspects staff work and adjusts lab policies and procedures if needed
    • Provide recommendations to group leaders with respect to daily operations, lab staff training status, and compliance with study protocols and center's policies and procedures
    • Review and oversee research protocols of internal and external research groups in an effort to stay abreast as to what research projects are occurring in the lab at any given time
    • Implements new programs, tests, methods, instrumentation, and procedures by investigating alternatives; preparing proposals; developing and performing parallel testing; monitoring progress
    • Anticipate the needs of the lab and prepare accordingly (order supplies, maintain inventory, consider budget implications, and coordinate equipment use)
    • Maintains the department productivity by monitoring workload of functional areas; identifying peak and slack periods; making operational or staffing adjustment
    • Maintains the department staff by recruiting, training, counseling and appraising activities results
    • Troubleshoot problems and recommend solutions to technical problems of extensive scope
    • Scientific and Administrative Department Point of Contact
    • Attend international conferences representing the department and committees meeting
    • Plan and schedule work activities to ensure adequate space, use of equipment, and coordination with other project activities within the lab
    • Perform other related duties and tasks as required or assigned

    REQUIREMENTS

    Education:
    • PhD in Computer Science, Biomedicine, Bioinformatics or related discipline
    Knowledge and Professional Experience:
    • A minimum of 5 years of directly related experience; or an equivalent combination of education, training and experience from which comparable knowledge, skills and abilities have been attained
    • Experience in Computational Biology/ Bioinformatics, Genomics and Machine learning methods
    Competences:
    • Demonstrated problem-solving skills, strong detail orientation and ability to adeptly manage multiple deadline dependent
    • Capacity to interact and build strong relations with a diverse members/stakeholder/staff base
    • Ability to communicate and interact effectively in verbal, written and presentation formats
    • Must be able to work cross functionally with other groups to achieve common goals
    • Excellent leadership and team building skills
    • Excellent written and verbal communication skills in English

    TERMS

    Conditions:
    • The position will be located at BSC within the Life Sciences department
    • A competitive salary will be provided, matched to the cost of living in Barcelona, depending on the value of the candidate
    • Duration of the contract: 2 years (with possibilities of extension)
    • Schedule: full time
    • Starting date: ASAP

    COMPENSATION

    30-40k

    HOW TO APPLY

    Center's Website: www.bsc.es/join[...]abman

    All applications must include:
    • A motivation letter
    • A full CV including contact details

    DEADLINE

    Monday, 13 March, 2017

    POLICY

    Diversity and Equal Opportunity Employment:
    BSC-CNS is an equal opportunity employer committed to diversity and inclusion. We are pleased to consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or any other basis protected by applicable state or local law.

    DESCRIPTION

    The Institute for Biostatistics and Informatics in Medicine and Ageing Research at the Rostock University Medical Center (Germany) seeks, starting as soon as possible,

    a Full-time Postdoctoral Scientific Researcher (E13/E14), with a focus on omics data analyses,

    initially for 4 years.

    Your tasks:
    • Advancement, adaptation and maintenance of an omics data analysis pipeline, with next-generation sequencing data (NGS) as its main focus
    • Sequencing data analysis, machine learning and data integration
    • Writing of scientific papers and grant applications, and contributions to joint papers and applications
    • Qualification towards Habilitation (post-doctoral degree certifying research and teaching expertise)
    Advantages for you:
    • A stimulating environment where your contribution can have a real impact
    • An exciting set of application areas, including aging, cancer, neuro and biomaterials research
    • Collaboration with experimental and clinical groups, marked by aiming at first/last authorships that count for your habilitation
    What you need to bring to the table:
    • Doctorate related to bioinformatics, or a research field in the medical/life/natural/mathematical sciences
    • Programming/scripting skills, preferably including expertise in R
    • Strong communication skills (oral presentations and in writing)

    HOW TO APPLY

    If this describes you and your intentions then please send your application at the latest until February 28, 2017 in a single PDF document, consisting of:
    • CV
    • Brief statement of research interests and qualifications
    • Contact information for 2-4 scientists who may write a letter of recommendation
    Please send your application to bioinfo-jobs[at]med.uni-rostock.de.

    For further information, please email bioinfo-jobs[at]med.uni-rostock.de, or call +49 381-494-7360.

    For most of the year, Rostock (at the Baltic Coast) is a number one vacation area in Germany, with a very pleasant climate and nice beaches nearby. The University strives for a high proportion of women in research and teaching.

    POLICY

    Applications from qualified female scientists are therefore particularly welcome. Disabled persons will be given preference in filling vacancies within the existing legal provisions if equally qualified. Reimbursement of travelling costs for interviews is not possible according to the rules of the state of Mecklenburg-Vorpommern.

    BACKGROUND

    Center for non-coding RNA in Technology and Health (RTH), rth.dk, Department of Veterinary and Animal Sciences, Faculty Health and Medical Sciences at University of Copenhagen has an open PhD position in RNA Bioinformatics in Bacillus and related Organisms. We are looking for an enthusiastic person to join our team for three years starting 1 March 2017 or as soon as possible thereafter. You will be a hardworking team player and a key person in the project group essential for obtaining successful results.

    Cell factories are based on organisms, which have been carefully optimised to produce protein-based products such as enzymes and pharmaceutical proteins with the highest possible yield. However, current technology is saturated with respect to yield improvement although the theoretical maximum has not been reached yet. Within the NextProd project, the goal is to improve the yield by manipulating ncRNAs. See more at nextprod.dk.

    RESPONSIBILITIES

    General Job Description:
    Your key tasks as a PhD fellow at Faculty of Health and Medical Sciences (SUND) are to:
    • Manage, carry through and conclude your research projects
    • Actively participate in PhD courses
    • Write scientific articles and finalise your PhD thesis
    • Participate in international congresses
    • Conduct a research stay at an institution abroad
    • Teach and disseminate your research
    Specific Job Description:
    Comprehensive annotation for noncoding and structured RNA on the bacillus gene is to be made from transcriptome data as well as from genomic data. In addition the include RNA interaction predictions and data when relevant. Pipeline that encompass known tools will be made. The pipeline will further include developing tools for integrating RNA structure probing data in the RNA structure annotation. Furthermore, the work will involve transcriptome and expression analyses. ncRNA RNA annotation and transcriptome analysis.

    REQUIREMENTS

    Required Qualifications:
    The applicant should hold professional as well as personal skills and qualifications as stated below:
    • A completed master degree in bioinformatics, computer science or a completed master degree in a similar area
    • General background knowledge of biological areas of genome structure and transcriptomes
    • Strong experience with script languages such as Perl or Python (or similar)
    • Strong experience with the Linux/Unix environment, command lines and shell scripting
    • Possess good interpersonal skills
    • Be excellent in English, writing and speech
    Candidates fulfilling one or more of the following qualifications will be prioritised:
    • Experience with RNA folding analysis
    • Experience with transcriptome analysis
    • Strong experience in at least one of the following programming languages: C, C++ or Java
    Formal Requirements:
    The position is available for a 3-year period for applicants holding a relevant master's degree.

    It is a prerequisite that the PhD candidate is enrolled as PhD student at the Faculty of Health and Medical Sciences, University of Copenhagen, according to the rules stipulated in "Bekendtgørelse nr. 18 af 14. januar 2008 om ph.d.-graden."

    PREFERENCES

    Key criteria for the assessment of candidates:
    • The grade point average achieved in relevant University degrees
    • Professional qualifications relevant to the PhD programme
    • Previous publications (if any)
    • Relevant work experience
    • Other professional activities
    • Language skills
    The successful candidate is also required to be resourceful and to possess good interpersonal skills.

    TERMS

    Terms of Employment:
    Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organisations. Depending on seniority, the monthly salary begins around 25.579 DKK (ca. 3.450 EUR) plus pension. The position is covered by the Job Structure for Academic Staff at Universities (2013).

    LOCALE

    Place of Employment:
    RTH is mainly located on the Frederiksberg Campus; however, as part of the NextProd project research stays with our industrial partner will be part of the PhD. Furthermore, our research environment is highly international and stimulating. We frequently organise seminars, workshops, PhD summer schools with international speakers and have retreats with our international collaborators.

    HOW TO APPLY

    Apply Online:
    employment.ku.dk/all-[...]84209

    Application Procedure:
    The application must be submitted in English, by clicking on "Apply online" below, and must include the following:
    • Cover Letter detailing your motivation and background for applying for the specific PhD project
    • CV
    • Diploma and detailed transcripts of records
    • Other information for consideration, e.g. list of publications (if any), peer reviewed and other
    • Personal Recommendations (if any)
    • A maximum of 3 relevant scientific works which the applicant wishes to be included in the assessment
    Questions:
    For further information about the Scientific content, please contact: Professor Jan Gorodkin, e-mail: gorodkin[at]rth.dk, phone +45 353 34704, +45 353 33578 (direct).

    Application procedure and formalities please contact: Administrative Officer, Marie-Louise Rosenlund, e-mail: mlr[at]sund.ku.dk, phone: +45 353 32898.

    The Further Process:
    Shortlist: After the expiry of the deadline for applications, the authorised recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at employment.ku.dk.

    Assessment: The selected applications will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities and the University of Copenhagen's guidelines 2013. The Assessment Committee makes a non-prioritised assessment of the academic qualifications and experience with respect to the mentioned area of research, techniques, skills and other requirements listed in the advertisement.

    Please note that the applicant will be contacted if the assessment committee requires further documentation.

    DEADLINE

    The deadline for applications is 5 March 2017. Any applications received after this time or incomplete will not be considered. Receipts of the applications will be acknowledged, and the applicant will be kept continuously informed of the progress of the application.

    POLICY

    The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.

    Part of the International Alliance of Research Universities (IARU), and among Europe's top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.
    Opportunity: Life Science Informatics @ OSTHUS GmbH -- Aachen, Germany
    Submitted by OSTHUS GmbH; posted on Wednesday, February 15, 2017

    BACKGROUND

    Are you looking for an exciting and rewarding career? We are looking for talented and passionate individuals. At OSTHUS you have the opportunity to be part of the future.

    OSTHUS is a leading consultant and software company supporting global leaders in scientific lab informatics with solutions that transform their business from initial research to end-product manufacturing. We are bringing innovative data-driven solutions to the world's largest research and development centers.

    RESPONSIBILITIES

    • Working on international consulting/IT projects with leading pharmaceutical and chemical companies
    • Supporting or leading the design and implementation of sophisticated business intelligence reports and visual analytics applications at enterprise scale
    • Analysis of lab data and IT systems
    • Working reliably on projects within a given time and budget frame whilst maintaining our quality standards

    REQUIREMENTS

    Required experience:
    • Completed study in either bioinformatics, cheminformatics, medical informatics or a closely related discipline, Ph.D. preferred
    • Possess 3 years of total professional experience in life science industries or consulting
    • Knowledge and practical understanding of visual analytics or business intelligence tools in life science, e.g. Spotfire, Tableau, Vortex, Pipeline Pilot, QlikView
    • A passion for IT; experience in programming/scripting languages and SQL-based databases
    • Very good verbal and written German and English language skills
    • Willingness to travel from time to time
    • A team player with the demonstrated ability to use flexible thinking to solve problems

    ABOUT US

    At OSTHUS:
    Our company believes in growing and supporting your individual strengths. OSTHUS offers training seminars and individual coaching in the areas of leadership, communication and organization. We provide you space to combine theory and practice, to contribute your potential and to expand your skills. Our open communication and transparent feedback culture, combined with flexibility, trust and responsibility, delivers the best performance from which customers, partners and employees all profit. We encourage people to be themselves. We give your ideas a chance to flourish.

    HOW TO APPLY

    E-Mail your résumé, your salary expectations and your desired starting date to career[at]osthus.com. Refer to "DTLD Life Science Informatics - Aachen" in the subject line.

    BACKGROUND

    The Institute for Genome Sciences (IGS) is led by Claire M. Fraser Ph.D., a preeminent genome scientist and microbiologist, and a team of investigators who have been working on the cutting edge of genomic research for the past 15 years. Members of the IGS team have helped revolutionize genomic discoveries in medicine, agriculture, environmental science and biodefense. By applying genomic tools to clinical research, these investigators are creating new dynamics for understanding individual differences in our susceptibility to disease, for understanding the role of our bodies' microorganisms in health and disease, and for exploring new personalized therapeutics. IGS investigators are also leading the development of the new field of microbial forensics.

    A Research Associate position is currently open in Dr. David Serre's laboratory at the Institute. The IGS at the University of Maryland, School of Medicine (UMSOM) is an interdisciplinary, multi-departmental team of collaborative investigators with a broad research program related to the genomics of infectious disease agents, human microbial metagenomics, human genomics, and bioinformatics. The impact of the members of IGS on the field of genomics has been substantial, with more than 500 publications during the past 15 years which have been cited more than 30,000 times.

    RESPONSIBILITIES

    We are looking for a researcher to lead the laboratory's projects on environmental DNA, develop new research directions and contribute to extramural grant writing.

    REQUIREMENTS

    The successful candidate should have a PhD in the life sciences, demonstrated experience with analysis of environmental DNA using next generation sequencing data, strong bioinformatics skills, and excellent communication skills and enthusiasm for scientific collaborations.

    LOCALE

    University of Maryland, School of Medicine, Baltimore, MD

    HOW TO APPLY

    To apply, please send a CV, detailing your list of publications, a cover letter describing your experience and statement of research interests (1-2 pages), and contact information for two references to IGS-jobs[at]som.umaryland.edu

    DEADLINE

    Consideration of candidates will begin upon receipt of applications and will be accepted through March 15, 2017. Anticipated start date for the positions is June 1, 2017.

    POLICY

    The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, veterans and individuals with disabilities are encouraged to apply.

    BACKGROUND

    The Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany has openings for two Bioinformaticians (f/m) to start as soon as possible for an initial period of two years.

    Our Institute investigates the molecular basis of the immune response and other topics of the developmental biology, such as the origin and differentiation of the immune cells as well as the development of vertebrate embryo. Another main focus of the Institute is Epigenetic. This area deals with inheritable traits, which are not caused by changes in the DNA sequence.

    RESPONSIBILITIES

    Your Opportunities:
    The successful candidate will work at the interface between the Bioinformatics Unit and leading experts in immunology and epigenetics. Specific projects include one or more of the following areas:
    • Epigenetic control of phenotypic variation
    • Analysis of RNA processing
    • Epigenetic dynamics at fertilization and at zygotic genome activation
    • Expression profiles of immune cell states
    You will have the opportunity to contribute directly to research projects from experimental design to data analysis and interpretation. Successful applicants will join a strong and interdisciplinary team that provides valuable know-how and access to a large Sequencing Facility (HiSeq3000, HiSeq2500, NextSeq) and a high-performance Data Center with Petabyte-scale storage solutions.

    REQUIREMENTS

    Your Qualifications:
    We are looking for motivated team players with strong communication skills and the desire to work in a dynamic and diverse environment. The candidate will have a good understanding of deep-sequencing technology and experience with the analysis of large-scale data. Given the large variety of research projects, we are looking for people who enjoy working in an interdisciplinary environment. Other requirements are:
    • MSc or PhD degree in Bioinformatics or equivalent experience in a related field
    • Proven expertise in programming and statistical analysis
    • Proficiency with Linux OS and in-depth IT-skills
    • Organizational talent and multi-tasking ability
    • Very good command of English language

    LOCALE

    Based within close vicinity to both France and Switzerland, our institute hosts a vibrant community of international researchers and many state-of-the-art facilities and modern office spaces. At the heart of the Black Forest, Freiburg offers a family-friendly atmosphere and excellent recreational possibilities for cultural and outdoor activities.

    COMPENSATION

    Our Offer:
    Salary will be based on previous experience according to TVöD guidelines.

    HOW TO APPLY

    Have we sparked your interest? Please submit your complete application (cover letter, CV, contact details of referees) via our online application portal (www.ie-freiburg.mpg.de/jobs) until February 20th, 2017. For informal inquiries please contact: manke[at]ie-freiburg.mpg.de.

    POLICY

    Handicapped applicants with equal qualifications will be given preferential treatment. The Max Planck Society seeks to increase the number of women in areas, where they are underrepresented, and therefore explicitly encourages women to apply. A childcare facility is directly attached to the institute.

    BACKGROUND

    An exciting opportunity has become available for a software developer/senior software developer to join the New Pipelines Group (NPG).

    The NPG group is a part of core sequencing informatics team at Wellcome Trust Sanger Institute. The group develops and maintains software for analysis and archival of sequencing and genotyping data produced by the high throughput facilities at the institute. Members of the team work in close collaboration with each other. Opportunities for professional growth are encouraged through formal and informal training, exposure to all elements of the software development cycle and work on diverse software projects. Most of the code developed by the team is available on GitHub: github.com/wtsi-npg

    RESPONSIBILITIES

    The successful candidate will work on a range of projects, such as (1) virtualising our computational pipelines and other software in order to make it run in standard manner on arbitrary hosts, including cloud, (2) highly efficient and scalable data streaming server and client applications, (3) analysis and QC pipelines, (4) applications for tracking sequencing instruments, (5) data archival, warehousing and visualisation.

    REQUIREMENTS

    We welcome applications equally from those who wish to work full time (37 hours) or for a minimum of 30 hours per week via a flexible working arrangement.

    Essential Skills:
    • An undergraduate or postgraduate degree in Computer Science (or similar), Bioinformatics or other science discipline
    • Competent in Python (virtualenv, pip), Node.js (streaming, Express, async, Promise), Perl (Moose, DBix::Class, CPAN)
    • Working knowledge of Linux OS and shell scripting (looping, conditions, error capture)
    • Experience of and/or interest to virtualization (VMs and/or Linux containers)
    • Experience of working with databases (using joins in relational databases, ORMs)
    • Use of version control software (Git)
    • Good written and verbal communication skills
    • Readiness to do self-directed learning
    • Attention to detail
    • Ability to work both on their own and as a part of a team

    PREFERENCES

    Ideal Skills:
    • Test automation and continuous integration
    • Web development and client side Javascript
    • Experience of working with large datasets (e.g. tens of thousands of 50 gigabyte files)
    • HPC under a job scheduler (LSF or OpenLava or other) or more contempory pipeline solutions e.g. Apache Spark
    • NoSQL databases (e.g. CouchDB, MongoDB)

    COMPENSATION

    Salary range: £24,589 to £39,729 pa depending on experience, plus excellent benefits

    The level of the appointment (developer or senior developer) will depend on the skills and qualifications of the successful candidate.

    Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

    ABOUT US

    The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

    The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to the Wellcome Genome Campus Courses, Conferences and Public Engagement (CCPE) programme. The CCPE programme delivers training and engagement focused around genomics, its applications, and implications. Its vision is to inspire a range of audiences both on the Campus and beyond it, and make the world of genomics open and accessible to all.

    To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops. In addition the Campus is home to the Wellcome Trust Advanced Course and Scientific Conferences programme and the Wellcome Trust Conference Centre.

    HOW TO APPLY

    Please include a covering letter and CV with your application.

    Apply via website: jobs.sanger.ac.uk/wd/p[...]02063

    DEADLINE

    Applications will be considered on an on-going basis.

    POLICY

    Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

    BACKGROUND

    We are seeking an individual who has a background in chemistry/biology or a related discipline, and some experience in the design and implementation of software solutions for processing, searching, display and analysis of data. You will develop software for analysis of data from mass spectrometry. You will also write programs, with guidance, to generate in silico datasets; develop software pipelines to upload and manage data and will, with support, be involved in curating information from existing sources.

    This role will work within a multidisciplinary team that includes scientists and informaticians.

    RESPONSIBILITIES

    Curating data, developing software and supporting the efforts of a team of programmers/curators as part of the international database project, LIPID MAPS (www.lipidmaps.org). Contributing to the design and development of new database/software catering for the analysis, integration and visualisation of lipidomic data derived from Mass Spectrometry (MS).

    LOCALE

    Cardiff University
    Division of Infection and Immunity
    School of Medicine
    College of Biomedical and Life Sciences
    Cardiff, UK

    HOW TO APPLY

    Please visit krb-sjobs.brassring.com/TGWe[...]=3594

    DEADLINE

    26 February 2017
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