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RESPONSIBILITIES:
In this role, you will lead the design, analysis, interpretation and reporting of pharmacokinetic/pharmacodynamic, drug disposition, and drug metabolism data from clinical studies for compounds in neuroscience diseases utilizing state of the art technology in support of clinical development plans. You will perform pharmacokinetic and pharmacodynamic modeling, contribute to PK/PD related regulatory documents and draft PK/PD sections in support of clinical development plans, and provide PK/PD perspective on cross functional teams.
You will also participate in regulatory interactions as needed as well as evaluate feasibility of clinical studies and provide input to the design and review of clinical protocols. In addition, you must be at the forefront of scientific literature in the areas of drug metabolism, pharmacokinetics, pharmacodynamics and clinical pharmacology.
REQUIREMENTS:
- A Ph.D. or a PharmD with a postdoctoral fellowship in Pharmacokinetics, Biopharmaceutics or a related field with a minimum of 3 years experience in pharmacokinetic, pharmacodynamic and drug metabolism techniques; at least one year of industry experience is highly desired.
- Direct experience designing, conducting and interpreting studies in population PK, PK/PD correlations, modeling and simulation utilizing state of the art applications is required.
- Candidate must display strong written and oral communication skills necessary to deliver scientific presentations.
- The ability to work in a dynamic team oriented environment as demonstrated by participating in and contributing to cross functional teams is necessary.
PREFERENCES:
- Having hands-on experience in modeling and simulation techniques, data interpretation and their application to the drug development process is highly desired.
- Experience in building an internal network of collaborators is desired.
LOCALE: Trenton, NJ
HOW TO APPLY:
To Apply For This Position Please Copy And Paste The Following URL Into Your Browser: [link]
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RESPONSIBILITIES:
The Department of Molecular and Cell Biology in the School of Natural Sciences and Mathematics at The University of Texas at Dallas seeks applications for a post-doctoral research scientist to support research of detecting fusion transcripts from RNA-seq data.
The successful candidate will join a computational biology team led by Dr. Xuan in new founded Center for Systems Biology and work on RNA-seq data analysis, especially to detect fusion-transcripts from cancer samples. The candidate will be also responsible for assisting in the supervision of doctoral students, developing new areas of research, and writing grant applications.
REQUIREMENTS:
- PhD degree in Bioinformatics, Computer Science or Applied Mathematics
- Self-motivated with excellent communication skills and an ability to interact with bench scientists and team members
- Experience in NGS data analysis
- Excellent programming skills in C/C++, Perl/Python
- Expertise with Linux /Unix environments
PREFERENCES:
- Background of molecular biology and microarray data analysis is preferred.
SALARY & BENEFITS:
Salary commensurate with experience.
HOW TO APPLY:
Applicants should submit a complete resume or curriculum vitae, including educational history and any pertinent work experience. Applicants should also submit three letters of reference. All application materials should be submitted via the ONLINE APPLICATION form ([link]). Indication of gender and ethnicity for affirmative action statistical purposes is requested as part of the application.
The University of Texas at Dallas is an Equal Opportunity / Affirmative Action University and strongly encourages applications from candidates who would enhance the diversity of the University¡¯s faculty and administration.
DEADLINE:
Review of applications will begin immediately and will continue until the position is filled. The starting date for this position is negotiable.
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RESPONSIBILITIES:
The Department of Molecular and Cell Biology in the School of Natural Sciences and Mathematics at The University of Texas at Dallas seeks applications for a post-doctoral research scientist to support research of detecting cancer-related variations from next-generation sequencing data.
The successful candidate will join a computational biology team led by Dr. Xuan in new founded Center for Systems Biology and work on next generation sequencing data analysis, especially to detect cancer related variants, with system biology methods. The candidate will be also responsible for assisting in the supervision of doctoral students, developing new areas of research, and writing grant applications.
REQUIREMENTS:
- PhD degree in Bioinformatics, Computer Science, Applied Mathematics, or Physics
- Self-motivated with excellent communication skills and an ability to interact with bench scientists and team members
- Strong background of statistics
- Excellent programming skills in C/C++, Perl/Python
- Expertise with Linux/Unix environments
PREFERENCES:
- Additional experience of network biology is a plus.
SALARY & BENEFITS:
Salary commensurate with experience.
HOW TO APPLY:
Applicants should submit a complete resume or curriculum vitae, including educational history and any pertinent work experience. Applicants should also submit three letters of reference. All application materials should be submitted via the ONLINE APPLICATION form ([link]). Indication of gender and ethnicity for affirmative action statistical purposes is requested as part of the application.
The University of Texas at Dallas is an Equal Opportunity / Affirmative Action University and strongly encourages applications from candidates who would enhance the diversity of the University's faculty and administration.
DEADLINE:
Review of applications will begin immediately and will continue until the position is filled. The starting date for this position is negotiable.
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BACKGROUND:
Cofactor Genomics is based in St. Louis, MO and provides sequencing and analysis services to academic and industry clients. We are a small company committed to changing the service sequencing paradigm by offering our customers front-to-back solutions; experimental design, next-generation sequencing, and advanced analytics for their work. Our dedication and constant attentiveness to customer needs, coupled with rapid technological integration, will help us to attain our goal of being an industry leader.
RESPONSIBILITIES:
We seek a talented bioinformatician to support and develop our Next-Generation DNA sequencing analysis applications. As an integral member of the Cofactor team you will help extend and automate our current set of analysis tools.
REQUIREMENTS:
- Skilled programmer in Perl, Java and/or C/C++.
- Excellent communication skills are a must. You will work both as part of the Cofactor team and with Cofactor's collaborators and customers.
PREFERENCES:
- Developers with previous experience and interest in DNA sequence analysis and next-generation sequencing technologies would be a plus.
LOCALE: Saint Louis, MO
SALARY & BENEFITS:
Salary will be based on applicants skill set and previous experience.
HOW TO APPLY:
For immediate consideration, please email a cover letter and resume to:
careers@cofactorgenomics.com
DEADLINE:
Applicants are encouraged to apply early. Cofactor intends to hire the first developer that is a good fit.
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RESPONSIBILITIES:
The Bioinformatics Shared Resource at Sanford|Burnham Institute for Medical Research is seeking an entry-level biostatistician/bioinformatician to assist scientists with statistics and to analyze microarray and Next-Gen sequencing data. Assist scientists with statistical data analysis, data interpretation and programming and analyze microarray and Next-Generation DNA sequencing data. The successful candidate will be responsible for statistical power analysis, determining statistically significant results (utilizing sample comparisons, ANOVA, regression and correlation analysis, etc.) and data analysis support for microarrays and Next-Gen sequencing.
Additional duties include providing training on biostatistics, assisting with writing grants, papers and preparations of data/illustrations for publications, as well as supporting a variety of bioinformatics projects. Some projects may require programming and web development.
REQUIREMENTS:
- A Bachelors degree in Biostatistics or Bioinformatics is required, a Masters degree is preferred.
- Previous experience and working knowledge of Linux/UNIX/Windows, Perl, Java, MySQL, CGI, HTML, and statistical software, such as Matlab or R is also required.
- Ability to communicate statistical concepts and data analysis interpretations to biology scientists is necessary.
- The successful candidate will have the ability to work independently, manage multiple projects, be a team player and have excellent verbal and written communication skills.
PREFERENCES:
- Hands-on experience with genomics and microarray data analysis and tools (e.g., GenePattern, Bioconductor, BLAST) is a plus.
TERMS: Full-Time position.
LOCALE: La Jolla, CA, US
HOW TO APPLY:
To submit your CV and apply for this job please go to [link] and apply on line (refer to bioinformatics.org in your application). Informal inquiries may be sent to eroshkin@burnham.org.
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RESPONSIBILITIES:
The Sr. Software Engineer is responsible for operating, supporting, maintaining, developing, integrating, and deploying software that supports the scientific mission of the JCVI. Software Engineers contribute to all phases of the software engineering lifecycle to maintain JCVI’s scientific leadership through the cost-effective application of software engineering tools and techniques.
QUALIFICATIONS:
- BS or MS in Computer Science/Software Engineering is required.
- Specific technical skills and experience pre-requisites will be established for each Software Engineer position, and may include some combination of the following:
-- Enterprise Java (Java, Javascript, JSP, Struts, Spring, EJB, MDB, Ajax, Hibernate) and associated tools and containers
-- C/C++ and associated tools
-- Relational Database (Oracle, Postgres, MySQL, and related tools including SQL and PL/SQL)
-- Bioinformatics tools and techniques
-- Scripting languages (Perl, Python, shell) and associated tools
-- Web technologies (HTML, DHTML, XML, CSS, and JavaScript) and Graphics tools (Photoshop, Image Ready, Fireworks or similar)
-- Data Modeling (UML, ER, Ontology-based) and Agile development practices
-- Operating Systems: UNIX and UNIX variants, Windows, Macintosh, and Grid technologies, including Sun Grid Engine
- Strong written and verbal communication skills
- Ability to collaborate across a multi-disciplinary team, and work independently
SALARY & BENEFITS:
JCVI offers an excellent working environment and a competitive benefits package.
HOW TO APPLY:
For more information and to apply to this position, please visit our website at http://www.jcvi.org.
Equal Opportunity Employer M/F/D/V.
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RESPONSIBILITIES:
The Bioinformatics Engineer is responsible for operating, supporting, maintaining, developing, integrating, and deploying bioinformatics tools and software supporting the scientific mission of the JCVI. Applicants should have substantial knowledge with genome-scale bioinformatics, including assembly, comparative genomics, analysis of protein families, multiple sequence alignment, and phylogenetic analyses. Bioinformatics Engineers contribute to all phases of the software engineering lifecycle to maintain JCVI’s scientific leadership through the cost-effective application of bioinformatics and software engineering tools and techniques to solve JCVI’s bioinformatics challenges.
REQUIREMENTS:
- BS or MS in Biology or Computer Science/Software Engineering (and a familiarity with the other discipline) is required.
- Specific technical skills and experience pre-requisites will be established for each Bioinformatics Engineer position, and may include some combination of the following:
-- Bioinformatics tools and techniques
-- Scripting languages (Perl, Python, shell) and associated tools
-- Web technologies (HTML, DHTML, XML, CSS, and JavaScript) and Graphics tools (Photoshop, Image Ready, Fireworks or similar)
-- Relational Database (Oracle, Postgres, MySQL, and related tools including SQL and PL/SQL) design, data warehousing
-- Data Modeling (UML, ER, Ontology-based) and Agile development practices
-- Operating Systems: UNIX and UNIX variants, Windows, Macintosh, and Grid technologies, including Sun Grid Engine
- Strong written and verbal communication skills
- Ability to collaborate across a multi-disciplinary team, and work independently
SALARY & BENEFITS:
JCVI offers an excellent working environment and a competitive benefits package.
HOW TO APPLY:
For more information and to apply to this position, please visit our website at http://www.jcvi.org.
Equal Opportunity Employer M/F/D/V.
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BACKGROUND:
Informatics is the largest department within the J. Craig Venter Institute (JCVI). This group includes bioinformatics scientists and software engineers who perform both federally funded R&D research to develop new tools for analysis of genomics data, as well as, service functions in support of JCVI research projects.
RESPONSIBILITIES:
JCVI is currently recruiting a postdoctoral fellow to work on the taxonomic classification of metagenomic sequences under the direction of Prof. Andrey Tovchigrechko. The initial focus of the project will be to develop new and apply existing machine learning algorithms for accurate high-throughput taxonomic classification of both assembled and unassembled metagenomes.
The postdoc will also have the opportunity to develop new bioinformatics research projects at the interface of sequence analysis, microbial and viral ecology, and machine learning. The candidate will contribute to the development of an open source toolbox for the taxonomic analysis of metagenomic data. This toolbox will include a high-performance computational back-end running on distributed resources such as NSF TeraGrid as well as a flexible Web front-end based on the Galaxy bioinformatics workbench.
REQUIREMENTS:
- Applicants are required to have a PhD in Bioinformatics, Computer Science, Engineering, Ecology, Computational Biology or related field.
PREFERENCES:
- Ideal candidates will demonstrate strong knowledge of scientific programming and prior exposure to research in the biological sciences.
- Good practical knowledge of programming in Python and C++ under Linux is strongly preferred.
- Other preferred skills include working knowledge of statistical theory and development of distributed pipelines in the Linux cluster environment.
TERMS:
The position is available immediately.
SALARY & BENEFITS:
JCVI offers an excellent working environment and a competitive benefits package.
HOW TO APPLY:
To apply, please fill out the online application form for position INFO735 at http://www.jcvi.org/ under the Careers tab. Please include a list of publications and the names of three professional references on your CV. Prospective applicants can also contact Andrey Tovchigrechko (atovtchi@jcvi.org) with more specific questions about the research project and qualifications requirements.
This position will be supported by the National Science Foundation grant 0850256 (the abstract is available at [link] ).
Equal Opportunity Employer M/F/D/V.
DEADLINE:
Applications will be reviewed upon receipt, and continue until the position is filled.
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RESPONSIBILITIES:
J. Craig Venter Institute (JCVI) is looking for two Post-Doctoral Fellows to join their Rockville, MD and San Diego, CA locations. The post-docs will provide an opportunity to work on several exciting metagenomic projects at JCVI. The responsibilities will include development of algorithms and statistical tools for analysis of metagenomic data generated by various high-throughput sequencing technologies. The areas of interest will include taxonomic and functional analysis, biodiversity estimation, sample comparison, and sequence assembly.
REQUIREMENTS:
- Qualified candidates will possess a Ph.D. in bioinformatics, computational biology, computer science, ecological or biological sciences or other disciplines providing training and experience in computer science and understanding of biology.
- A strong demonstrated computer programming experience, including knowledge of major programming languages: compiled (C/C++ or Java), scripting (Perl or Python) and SQL
- Ability to perform basic molecular biology techniques is desired (applies to the Rockville, MD position only)
SALARY & BENEFITS:
JCVI offers an excellent working environment and a competitive benefits package.
HOW TO APPLY:
For more information and to apply to this position, please visit our website at http://www.jcvi.org
Equal Opportunity Employer M/F/D/V.
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RESPONSIBILITIES:
We seek a talented Bioinformatician or Statistician and experienced R programmer with experience in the analysis of expression microarray and/or other high-throughput biological data sets to assist with a variety of integrative genomic analyses in human populations. The scope of work will include differential gene expression analysis, network modeling, sequence annotation, and eQTL studies.
Duties:
- Aid in developing, writing, testing, and implementing scientific programs to simulate and/or analyze genetic and expression data. Including Network modeling and sequence annotation.
- Support and conduct statistical analyses for epidemiologists and geneticists, including data manipulation required prior to implementing statistical software.
- Perform quality control evaluations for expression, CNV and genetic data.
- Assist in defining and analyzing experiments for research.
- Study and modify existing programs to solve specific problems.
- Develop new programs from specifications.
- Prepare documentation of completed analyses and present to team lead.
- Must be able to handle multiple long term projects simultaneously and be able to budget time effectively.
REQUIREMENTS:
- Masters in Statistics. Computer Science, Mathematics or a Physical science preferred, with strong background in applied data analysis.
- Must have at least 2 years of programming in R or SAS; Experience in a scripting language such as Perl or Python.
Skills:
- Comfortable in both a PC and Linux computing environment
- Proficiency in R statistics package
- Excellent communication and documentation skills
- Strong initiative and demonstrated ability to take ownership of challenging problems
PREFERENCES:
- Experience in analysis of microarray data and Bioconductor program a strong plus.
SALARY & BENEFITS: Salary is DOE.
HOW TO APPLY:
Please email aarons@fcstaffing.com or call 1-888-989-1888 and ask for Aaron Schindler to discuss.
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