Basic Information
Gene ID 100350717
Gene Name E2F8
Full Name Uncharacterized protein
Organism Oryctolagus cuniculus [9986]

Cross Reference
UniProt G1SLW9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOCUP00000003874 Gene3D G3DSA:1.10.10.10 IPR011991 113 189 1.30e-24 Winged helix-turn-helix DNA-binding domain
ENSOCUP00000003874 Gene3D G3DSA:1.10.10.10 IPR011991 264 354 1.30e-22 Winged helix-turn-helix DNA-binding domain
ENSOCUP00000003874 PANTHER PTHR12081 IPR015633 1 766 0.00e-00 E2F Family
ENSOCUP00000003874 Pfam PF02319 IPR003316 118 187 6.80e-21 Transcription factor E2F/dimerisation partner (TDP)
ENSOCUP00000003874 Pfam PF02319 IPR003316 266 352 6.40e-19 Transcription factor E2F/dimerisation partner (TDP)

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOCUP00000003874 PF02319 1.60028e-42 E2F_TDP E2F/DP family winged-helix DNA-binding domain
ENSOCUP00000003874 PF01978 0.00019 TrmB Sugar-specific transcriptional regulator TrmB

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOCUP00000003874 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSOCUP00000003874 GO:0001890 biological_process placenta development
ENSOCUP00000003874 GO:0002040 biological_process sprouting angiogenesis
ENSOCUP00000003874 GO:0006351 biological_process transcription, DNA-templated
ENSOCUP00000003874 GO:0032466 biological_process negative regulation of cytokinesis
ENSOCUP00000003874 GO:0032877 biological_process positive regulation of DNA endoreduplication
ENSOCUP00000003874 GO:0060707 biological_process trophoblast giant cell differentiation
ENSOCUP00000003874 GO:0060718 biological_process chorionic trophoblast cell differentiation
ENSOCUP00000003874 GO:0070365 biological_process hepatocyte differentiation
ENSOCUP00000003874 GO:0005634 cellular_component nucleus
ENSOCUP00000003874 GO:0005667 cellular_component transcription factor complex
ENSOCUP00000003874 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOCUP00000003874 GO:0003714 molecular_function transcription corepressor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100071962 10029 Cricetulus griseus 100760871
9685 Felis catus 101082690 10090 Mus musculus 108961
9978 Ochotona princeps ENSOPRG00000012881 31033 Takifugu rubripes ENSTRUG00000015792
9478 Tarsius syrichta ENSTSYG00000007279 9739 Tursiops truncatus ENSTTRG00000005707
9483 Callithrix jacchus 100408568 9597 Pan paniscus 100970405
9555 Papio anubis 101024508 39432 Saimiri boliviensis 101053563
9595 Gorilla gorilla 101153297 9669 Mustela putorius furo 101693740
59463 Myotis lucifugus 102437294 9606 Homo sapiens 79733
28377 Anolis carolinensis ENSACAG00000015743 9358 Choloepus hoffmanni ENSCHOG00000006322
7719 Ciona intestinalis ENSCING00000014484 10141 Cavia porcellus ENSCPOG00000013766
9361 Dasypus novemcinctus ENSDNOG00000003349 10020 Dipodomys ordii ENSDORG00000000040
9365 Erinaceus europaeus ENSEEUG00000011472 9371 Echinops telfairi ENSETEG00000004363
69293 Gasterosteus aculeatus ENSGACG00000017086 9031 Gallus gallus ENSGALG00000004023
8049 Gadus morhua ENSGMOG00000019253 7897 Latimeria chalumnae ENSLACG00000016113
9785 Loxodonta africana ENSLAFG00000022713 9315 Macropus eugenii ENSMEUG00000013506
9103 Meleagris gallopavo ENSMGAG00000002303 30608 Microcebus murinus ENSMICG00000017089
9544 Macaca mulatta ENSMMUG00000010853 9258 Ornithorhynchus anatinus ENSOANG00000011290
30611 Otolemur garnettii ENSOGAG00000005774 8128 Oreochromis niloticus ENSONIG00000007135
8090 Oryzias latipes ENSORLG00000000786 9813 Procavia capensis ENSPCAG00000003996
13735 Pelodiscus sinensis ENSPSIG00000008707 132908 Pteropus vampyrus ENSPVAG00000012522
10116 Rattus norvegicus ENSRNOG00000022537 9305 Sarcophilus harrisii ENSSHAG00000018372
43179 Ictidomys tridecemlineatus ENSSTOG00000008838 37347 Tupaia belangeri ENSTBEG00000005521
59729 Taeniopygia guttata ENSTGUG00000015857 99883 Tetraodon nigroviridis ENSTNIG00000009615
30538 Vicugna pacos ENSVPAG00000012423 8364 Xenopus tropicalis ENSXETG00000004436
8083 Xiphophorus maculatus ENSXMAG00000010237