Basic Information
Gene ID 108961 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name E2f8
Full Name Transcription factor E2F8
Organism Mus musculus [10090]

Cross Reference
UniProt Q58FA4 UniGene Mm.240566
PDB 1WZH OMIM NULL
KEGG mmu:108961 UCSC uc009haz.2

Protein Interactions
DIP NULL
IntAct Q58FA4
MINT MINT-8410110
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000112883 Gene3D G3DSA:1.10.10.10 IPR011991 108 184 1.10e-24 Winged helix-turn-helix DNA-binding domain
ENSMUSP00000112883 Gene3D G3DSA:1.10.10.10 IPR011991 259 349 1.30e-22 Winged helix-turn-helix DNA-binding domain
ENSMUSP00000112883 PANTHER PTHR12081 IPR015633 1 758 0.00e-00 E2F Family
ENSMUSP00000112883 Pfam PF02319 IPR003316 113 182 2.90e-21 Transcription factor E2F/dimerisation partner (TDP)
ENSMUSP00000112883 Pfam PF02319 IPR003316 261 347 9.80e-19 Transcription factor E2F/dimerisation partner (TDP)

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000112883 PF02319 1.19951e-42 E2F_TDP E2F/DP family winged-helix DNA-binding domain
ENSMUSP00000112883 PF01978 0.0002 TrmB Sugar-specific transcriptional regulator TrmB

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000112883 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSMUSP00000112883 GO:0001890 biological_process placenta development
ENSMUSP00000112883 GO:0002040 biological_process sprouting angiogenesis
ENSMUSP00000112883 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000112883 GO:0032466 biological_process negative regulation of cytokinesis
ENSMUSP00000112883 GO:0032877 biological_process positive regulation of DNA endoreduplication
ENSMUSP00000112883 GO:0060707 biological_process trophoblast giant cell differentiation
ENSMUSP00000112883 GO:0060718 biological_process chorionic trophoblast cell differentiation
ENSMUSP00000112883 GO:0070365 biological_process hepatocyte differentiation
ENSMUSP00000112883 GO:0005634 cellular_component nucleus
ENSMUSP00000112883 GO:0005667 cellular_component transcription factor complex
ENSMUSP00000112883 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000112883 GO:0003714 molecular_function transcription corepressor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100071962 7425 Nasonia vitripennis 100119031
9986 Oryctolagus cuniculus 100350717 9483 Callithrix jacchus 100408568
10029 Cricetulus griseus 100760871 9597 Pan paniscus 100970405
9555 Papio anubis 101024508 39432 Saimiri boliviensis 101053563
9595 Gorilla gorilla 101153297 9669 Mustela putorius furo 101693740
59463 Myotis lucifugus 102437294 9685 Felis catus 101082690
6239 Caenorhabditis elegans 174341 9978 Ochotona princeps ENSOPRG00000012881
9478 Tarsius syrichta ENSTSYG00000007279 9739 Tursiops truncatus ENSTTRG00000005707
9606 Homo sapiens 79733 28377 Anolis carolinensis ENSACAG00000015743
9358 Choloepus hoffmanni ENSCHOG00000006322 10141 Cavia porcellus ENSCPOG00000013766
9361 Dasypus novemcinctus ENSDNOG00000003349 10020 Dipodomys ordii ENSDORG00000000040
9365 Erinaceus europaeus ENSEEUG00000011472 9371 Echinops telfairi ENSETEG00000004363
69293 Gasterosteus aculeatus ENSGACG00000017086 9031 Gallus gallus ENSGALG00000004023
8049 Gadus morhua ENSGMOG00000019253 7897 Latimeria chalumnae ENSLACG00000016113
9785 Loxodonta africana ENSLAFG00000022713 9315 Macropus eugenii ENSMEUG00000013506
9103 Meleagris gallopavo ENSMGAG00000002303 30608 Microcebus murinus ENSMICG00000017089
9544 Macaca mulatta ENSMMUG00000010853 9258 Ornithorhynchus anatinus ENSOANG00000011290
30611 Otolemur garnettii ENSOGAG00000005774 8128 Oreochromis niloticus ENSONIG00000007135
8090 Oryzias latipes ENSORLG00000000786 9813 Procavia capensis ENSPCAG00000003996
13735 Pelodiscus sinensis ENSPSIG00000008707 132908 Pteropus vampyrus ENSPVAG00000012522
10116 Rattus norvegicus ENSRNOG00000022537 9305 Sarcophilus harrisii ENSSHAG00000018372
43179 Ictidomys tridecemlineatus ENSSTOG00000008838 37347 Tupaia belangeri ENSTBEG00000005521
59729 Taeniopygia guttata ENSTGUG00000015857 99883 Tetraodon nigroviridis ENSTNIG00000009615
31033 Takifugu rubripes ENSTRUG00000015792 30538 Vicugna pacos ENSVPAG00000012423
8364 Xenopus tropicalis ENSXETG00000004436 8083 Xiphophorus maculatus ENSXMAG00000010237