Basic Information
Gene ID ENSLAFG00000022713
Gene Name E2F8
Full Name Uncharacterized protein
Organism Loxodonta africana [9785]

Cross Reference
UniProt G3TQ84 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLAFP00000028399 Gene3D G3DSA:1.10.10.10 IPR011991 108 184 1.30e-24 Winged helix-turn-helix DNA-binding domain
ENSLAFP00000028399 Gene3D G3DSA:1.10.10.10 IPR011991 259 349 1.30e-22 Winged helix-turn-helix DNA-binding domain
ENSLAFP00000028399 PANTHER PTHR12081 IPR015633 1 763 0.00e-00 E2F Family
ENSLAFP00000028399 Pfam PF02319 IPR003316 113 182 6.80e-21 Transcription factor E2F/dimerisation partner (TDP)
ENSLAFP00000028399 Pfam PF02319 IPR003316 261 347 6.30e-19 Transcription factor E2F/dimerisation partner (TDP)

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLAFP00000028399 PF02319 1.49939e-42 E2F_TDP E2F/DP family winged-helix DNA-binding domain
ENSLAFP00000028399 PF01978 0.00021 TrmB Sugar-specific transcriptional regulator TrmB

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLAFP00000028399 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSLAFP00000028399 GO:0001890 biological_process placenta development
ENSLAFP00000028399 GO:0002040 biological_process sprouting angiogenesis
ENSLAFP00000028399 GO:0006351 biological_process transcription, DNA-templated
ENSLAFP00000028399 GO:0032466 biological_process negative regulation of cytokinesis
ENSLAFP00000028399 GO:0032877 biological_process positive regulation of DNA endoreduplication
ENSLAFP00000028399 GO:0060707 biological_process trophoblast giant cell differentiation
ENSLAFP00000028399 GO:0060718 biological_process chorionic trophoblast cell differentiation
ENSLAFP00000028399 GO:0070365 biological_process hepatocyte differentiation
ENSLAFP00000028399 GO:0005634 cellular_component nucleus
ENSLAFP00000028399 GO:0005667 cellular_component transcription factor complex
ENSLAFP00000028399 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSLAFP00000028399 GO:0003714 molecular_function transcription corepressor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9595 Gorilla gorilla 101153297 28377 Anolis carolinensis ENSACAG00000015743
51511 Ciona savignyi ENSCSAVG00000010123 9361 Dasypus novemcinctus ENSDNOG00000003349
9365 Erinaceus europaeus ENSEEUG00000011472 69293 Gasterosteus aculeatus ENSGACG00000017086
9031 Gallus gallus ENSGALG00000004023 9796 Equus caballus 100071962
7425 Nasonia vitripennis 100119031 9986 Oryctolagus cuniculus 100350717
9483 Callithrix jacchus 100408568 10029 Cricetulus griseus 100760871
7668 Strongylocentrotus purpuratus 100891325 9597 Pan paniscus 100970405
9555 Papio anubis 101024508 39432 Saimiri boliviensis 101053563
9685 Felis catus 101082690 9669 Mustela putorius furo 101693740
59463 Myotis lucifugus 102437294 10090 Mus musculus 108961
9606 Homo sapiens 79733 9358 Choloepus hoffmanni ENSCHOG00000006322
7719 Ciona intestinalis ENSCING00000014484 10141 Cavia porcellus ENSCPOG00000013766
10020 Dipodomys ordii ENSDORG00000000040 9371 Echinops telfairi ENSETEG00000004363
8049 Gadus morhua ENSGMOG00000019253 7897 Latimeria chalumnae ENSLACG00000016113
9315 Macropus eugenii ENSMEUG00000013506 30608 Microcebus murinus ENSMICG00000017089
9544 Macaca mulatta ENSMMUG00000010853 9258 Ornithorhynchus anatinus ENSOANG00000011290
30611 Otolemur garnettii ENSOGAG00000005774 8128 Oreochromis niloticus ENSONIG00000007135
9978 Ochotona princeps ENSOPRG00000012881 9813 Procavia capensis ENSPCAG00000003996
13735 Pelodiscus sinensis ENSPSIG00000008707 10116 Rattus norvegicus ENSRNOG00000022537
43179 Ictidomys tridecemlineatus ENSSTOG00000008838 37347 Tupaia belangeri ENSTBEG00000005521
99883 Tetraodon nigroviridis ENSTNIG00000009615 31033 Takifugu rubripes ENSTRUG00000015792
9478 Tarsius syrichta ENSTSYG00000007279 9739 Tursiops truncatus ENSTTRG00000005707
30538 Vicugna pacos ENSVPAG00000012423 8364 Xenopus tropicalis ENSXETG00000004436
9103 Meleagris gallopavo ENSMGAG00000002303 8090 Oryzias latipes ENSORLG00000000786
132908 Pteropus vampyrus ENSPVAG00000012522 9305 Sarcophilus harrisii ENSSHAG00000018372
59729 Taeniopygia guttata ENSTGUG00000015857 8083 Xiphophorus maculatus ENSXMAG00000010237