Basic Information
Gene ID 102462741
Gene Name STAT1
Full Name Signal transducer and activator of transcription
Organism Pelodiscus sinensis [13735]

Cross Reference
UniProt K7FU55 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPSIP00000011565 Gene3D G3DSA:1.10.238.10 IPR011992 461 583 8.30e-50 EF-hand domain pair
ENSPSIP00000011565 Gene3D G3DSA:1.10.532.10 IPR013799 1 120 6.70e-46 STAT transcription factor, protein interaction
ENSPSIP00000011565 Gene3D G3DSA:1.20.1050.20 IPR013800 137 317 1.00e-64 STAT transcription factor, all-alpha
ENSPSIP00000011565 Gene3D G3DSA:2.60.40.630 IPR012345 318 460 3.90e-65 STAT transcription factor, DNA-binding, subdomain
ENSPSIP00000011565 Gene3D G3DSA:3.30.505.10 IPR000980 584 711 1.20e-51 SH2 domain
ENSPSIP00000011565 PANTHER PTHR11801 IPR001217 2 747 0.00e-00 Transcription factor STAT
ENSPSIP00000011565 Pfam PF00017 IPR000980 580 639 4.70e-09 SH2 domain
ENSPSIP00000011565 Pfam PF01017 IPR013800 137 315 7.60e-68 STAT transcription factor, all-alpha
ENSPSIP00000011565 Pfam PF02864 IPR013801 317 569 3.10e-117 STAT transcription factor, DNA-binding
ENSPSIP00000011565 Pfam PF02865 IPR013799 2 120 1.40e-42 STAT transcription factor, protein interaction
ENSPSIP00000011565 Pfam PF12162 IPR022752 715 739 3.20e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
ENSPSIP00000011565 ProSiteProfiles PS50001 IPR000980 575 681 0.00e-00 SH2 domain
ENSPSIP00000011565 SMART SM00252 IPR000980 573 657 7.60e-04 SH2 domain
ENSPSIP00000011565 SMART SM00964 IPR013799 2 122 4.40e-67 STAT transcription factor, protein interaction
ENSPSIP00000011565 SUPERFAMILY SSF47655 IPR015988 134 317 0.00e-00 STAT transcription factor, coiled coil
ENSPSIP00000011565 SUPERFAMILY SSF48092 IPR013799 1 120 0.00e-00 STAT transcription factor, protein interaction
ENSPSIP00000011565 SUPERFAMILY SSF49417 IPR008967 317 570 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPSIP00000011565 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSPSIP00000011565 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSPSIP00000011565 PF02865 1.3999e-42 STAT_int STAT protein, protein interaction domain
ENSPSIP00000011565 PF12162 1.6e-12 STAT1_TAZ2bind STAT1 TAZ2 binding domain
ENSPSIP00000011565 PF00017 1.1e-09 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPSIP00000011565 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSPSIP00000011565 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPSIP00000011565 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSPSIP00000011565 GO:0005634 cellular_component nucleus
ENSPSIP00000011565 GO:0005737 cellular_component cytoplasm
ENSPSIP00000011565 GO:0003677 molecular_function DNA binding
ENSPSIP00000011565 GO:0004871 molecular_function signal transducer activity
ENSPSIP00000011565 GO:0005509 molecular_function calcium ion binding
ENSPSIP00000011565 GO:0019901 molecular_function protein kinase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100121885 7029 Acyrthosiphon pisum 100161101
6087 Hydra magnipapillata 100206878 30195 Bombus terrestris 100647789
132113 Bombus impatiens 100743540 34638 Metaseiulus occidentalis 100907401
9597 Pan paniscus 100971620 9555 Papio anubis 101005886
7897 Latimeria chalumnae 102353760 9483 Callithrix jacchus 100402355
400682 Amphimedon queenslandica 100641588 8128 Oreochromis niloticus 100696359
10029 Cricetulus griseus 100755609 7463 Apis florea 100864112
143995 Megachile rotundata 100880948 39432 Saimiri boliviensis 101030811
7460 Apis mellifera 413742 7070 Tribolium castaneum 657965
9544 Macaca mulatta 693650 28377 Anolis carolinensis ENSACAG00000005909
9365 Erinaceus europaeus ENSEEUG00000002778 9031 Gallus gallus ENSGALG00000007651
8049 Gadus morhua ENSGMOG00000012431 9103 Meleagris gallopavo ENSMGAG00000006382
9669 Mustela putorius furo ENSMPUG00000012530 9258 Ornithorhynchus anatinus ENSOANG00000022638
9986 Oryctolagus cuniculus ENSOCUG00000002455 30611 Otolemur garnettii ENSOGAG00000003038
8090 Oryzias latipes ENSORLG00000000162 9601 Pongo abelii ENSPPYG00000013027
9598 Pan troglodytes ENSPTRG00000012749 99883 Tetraodon nigroviridis ENSTNIG00000017161
10090 Mus musculus 20849 10116 Rattus norvegicus 25124
7227 Drosophila melanogaster 42428 9913 Bos taurus 510814
7668 Strongylocentrotus purpuratus 576433 9606 Homo sapiens 6775
9646 Ailuropoda melanoleuca ENSAMEG00000014048 9358 Choloepus hoffmanni ENSCHOG00000013865
10141 Cavia porcellus ENSCPOG00000012673 7955 Danio rerio ENSDARG00000006266
9361 Dasypus novemcinctus ENSDNOG00000007325 10020 Dipodomys ordii ENSDORG00000011139
9796 Equus caballus ENSECAG00000009039 9371 Echinops telfairi ENSETEG00000017040
9685 Felis catus ENSFCAG00000013725 69293 Gasterosteus aculeatus ENSGACG00000015589
9595 Gorilla gorilla ENSGGOG00000000611 9785 Loxodonta africana ENSLAFG00000001475
9315 Macropus eugenii ENSMEUG00000012165 30608 Microcebus murinus ENSMICG00000002941
59463 Myotis lucifugus ENSMLUG00000010083 13616 Monodelphis domestica ENSMODG00000011747
61853 Nomascus leucogenys ENSNLEG00000006694 9978 Ochotona princeps ENSOPRG00000008589
9813 Procavia capensis ENSPCAG00000007855 7757 Petromyzon marinus ENSPMAG00000002770
132908 Pteropus vampyrus ENSPVAG00000004735 9305 Sarcophilus harrisii ENSSHAG00000016913
9823 Sus scrofa ENSSSCG00000016057 43179 Ictidomys tridecemlineatus ENSSTOG00000008620
37347 Tupaia belangeri ENSTBEG00000017412 59729 Taeniopygia guttata ENSTGUG00000010768
31033 Takifugu rubripes ENSTRUG00000000102 9478 Tarsius syrichta ENSTSYG00000007651
9739 Tursiops truncatus ENSTTRG00000001134 30538 Vicugna pacos ENSVPAG00000011543
8364 Xenopus tropicalis ENSXETG00000004649 8083 Xiphophorus maculatus ENSXMAG00000001594