Basic Information | |||
Gene ID | ENSOCUG00000002455 | ||
Gene Name | STAT1 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Oryctolagus cuniculus [9986] |
Cross Reference | |||
UniProt | G1SHL8 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSOCUP00000002129 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 467 | 587 | 3.10e-50 | EF-hand domain pair |
ENSOCUP00000002129 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 121 | 1.50e-47 | STAT transcription factor, protein interaction |
ENSOCUP00000002129 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 137 | 317 | 5.70e-69 | STAT transcription factor, all-alpha |
ENSOCUP00000002129 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 318 | 466 | 9.60e-63 | STAT transcription factor, DNA-binding, subdomain |
ENSOCUP00000002129 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 588 | 717 | 1.70e-52 | SH2 domain |
ENSOCUP00000002129 | PANTHER | PTHR11801 | IPR001217 | 2 | 756 | 0.00e-00 | Transcription factor STAT |
ENSOCUP00000002129 | Pfam | PF00017 | IPR000980 | 584 | 644 | 7.00e-09 | SH2 domain |
ENSOCUP00000002129 | Pfam | PF01017 | IPR013800 | 137 | 315 | 1.90e-65 | STAT transcription factor, all-alpha |
ENSOCUP00000002129 | Pfam | PF02864 | IPR013801 | 317 | 573 | 7.90e-115 | STAT transcription factor, DNA-binding |
ENSOCUP00000002129 | Pfam | PF02865 | IPR013799 | 2 | 121 | 7.90e-44 | STAT transcription factor, protein interaction |
ENSOCUP00000002129 | Pfam | PF12162 | IPR022752 | 721 | 743 | 1.70e-10 | Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal |
ENSOCUP00000002129 | ProSiteProfiles | PS50001 | IPR000980 | 579 | 676 | 0.00e-00 | SH2 domain |
ENSOCUP00000002129 | SMART | SM00252 | IPR000980 | 577 | 693 | 5.60e-04 | SH2 domain |
ENSOCUP00000002129 | SMART | SM00964 | IPR013799 | 2 | 122 | 1.90e-67 | STAT transcription factor, protein interaction |
ENSOCUP00000002129 | SUPERFAMILY | SSF47655 | IPR015988 | 134 | 317 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSOCUP00000002129 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 121 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSOCUP00000002129 | SUPERFAMILY | SSF49417 | IPR008967 | 317 | 574 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSOCUP00000002129 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
ENSOCUP00000002129 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSOCUP00000002129 | PF02865 | 7.84727e-44 | STAT_int | STAT protein, protein interaction domain |
ENSOCUP00000002129 | PF12162 | 6.8e-11 | STAT1_TAZ2bind | STAT1 TAZ2 binding domain |
ENSOCUP00000002129 | PF00017 | 1.2e-09 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSOCUP00000002129 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
ENSOCUP00000002129 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
ENSOCUP00000002129 | GO:0060397 | biological_process | JAK-STAT cascade involved in growth hormone signaling pathway |
ENSOCUP00000002129 | GO:0005634 | cellular_component | nucleus |
ENSOCUP00000002129 | GO:0005737 | cellular_component | cytoplasm |
ENSOCUP00000002129 | GO:0003677 | molecular_function | DNA binding |
ENSOCUP00000002129 | GO:0004871 | molecular_function | signal transducer activity |
ENSOCUP00000002129 | GO:0005509 | molecular_function | calcium ion binding |
ENSOCUP00000002129 | GO:0019901 | molecular_function | protein kinase binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
8128 | Oreochromis niloticus | 100696359 | 10029 | Cricetulus griseus | 100755609 |
9597 | Pan paniscus | 100971620 | 9555 | Papio anubis | 101005886 |
39432 | Saimiri boliviensis | 101030811 | 7897 | Latimeria chalumnae | 102353760 |
13735 | Pelodiscus sinensis | 102462741 | 10090 | Mus musculus | 20849 |
10116 | Rattus norvegicus | 25124 | 9913 | Bos taurus | 510814 |
9606 | Homo sapiens | 6775 | 9544 | Macaca mulatta | 693650 |
28377 | Anolis carolinensis | ENSACAG00000005909 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000014048 |
9358 | Choloepus hoffmanni | ENSCHOG00000013865 | 10141 | Cavia porcellus | ENSCPOG00000012673 |
7955 | Danio rerio | ENSDARG00000006266 | 9361 | Dasypus novemcinctus | ENSDNOG00000007325 |
10020 | Dipodomys ordii | ENSDORG00000011139 | 9796 | Equus caballus | ENSECAG00000009039 |
9371 | Echinops telfairi | ENSETEG00000017040 | 9685 | Felis catus | ENSFCAG00000013725 |
69293 | Gasterosteus aculeatus | ENSGACG00000015589 | 9595 | Gorilla gorilla | ENSGGOG00000000611 |
9785 | Loxodonta africana | ENSLAFG00000001475 | 9315 | Macropus eugenii | ENSMEUG00000012165 |
30608 | Microcebus murinus | ENSMICG00000002941 | 59463 | Myotis lucifugus | ENSMLUG00000010083 |
13616 | Monodelphis domestica | ENSMODG00000011747 | 61853 | Nomascus leucogenys | ENSNLEG00000006694 |
9483 | Callithrix jacchus | 100402355 | 9365 | Erinaceus europaeus | ENSEEUG00000002197 |
9031 | Gallus gallus | ENSGALG00000007651 | 8049 | Gadus morhua | ENSGMOG00000012431 |
9103 | Meleagris gallopavo | ENSMGAG00000006382 | 9669 | Mustela putorius furo | ENSMPUG00000012530 |
9258 | Ornithorhynchus anatinus | ENSOANG00000022638 | 30611 | Otolemur garnettii | ENSOGAG00000003038 |
8090 | Oryzias latipes | ENSORLG00000000162 | 9601 | Pongo abelii | ENSPPYG00000013027 |
9598 | Pan troglodytes | ENSPTRG00000012749 | 9978 | Ochotona princeps | ENSOPRG00000008589 |
9813 | Procavia capensis | ENSPCAG00000005867 | 7757 | Petromyzon marinus | ENSPMAG00000002770 |
132908 | Pteropus vampyrus | ENSPVAG00000004735 | 9305 | Sarcophilus harrisii | ENSSHAG00000016913 |
9823 | Sus scrofa | ENSSSCG00000016057 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000008620 |
37347 | Tupaia belangeri | ENSTBEG00000017412 | 59729 | Taeniopygia guttata | ENSTGUG00000010768 |
99883 | Tetraodon nigroviridis | ENSTNIG00000017161 | 31033 | Takifugu rubripes | ENSTRUG00000000102 |
9478 | Tarsius syrichta | ENSTSYG00000007651 | 9739 | Tursiops truncatus | ENSTTRG00000001134 |
30538 | Vicugna pacos | ENSVPAG00000011543 | 8364 | Xenopus tropicalis | ENSXETG00000004649 |
8083 | Xiphophorus maculatus | ENSXMAG00000001594 |