Basic Information
Gene ID ENSTNIG00000017161
Gene Name STAT1
Full Name Signal transducer and activator of transcription
Organism Tetraodon nigroviridis [99883]

Cross Reference
UniProt H3C088 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTNIP00000020297 Gene3D G3DSA:1.10.238.10 IPR011992 457 579 2.10e-48 EF-hand domain pair
ENSTNIP00000020297 Gene3D G3DSA:1.10.532.10 IPR013799 1 121 4.60e-42 STAT transcription factor, protein interaction
ENSTNIP00000020297 Gene3D G3DSA:1.20.1050.20 IPR013800 137 314 9.90e-55 STAT transcription factor, all-alpha
ENSTNIP00000020297 Gene3D G3DSA:2.60.40.630 IPR012345 316 456 6.90e-58 STAT transcription factor, DNA-binding, subdomain
ENSTNIP00000020297 Gene3D G3DSA:3.30.505.10 IPR000980 580 708 1.30e-55 SH2 domain
ENSTNIP00000020297 PANTHER PTHR11801 IPR001217 2 758 0.00e-00 Transcription factor STAT
ENSTNIP00000020297 Pfam PF00017 IPR000980 576 648 1.00e-09 SH2 domain
ENSTNIP00000020297 Pfam PF01017 IPR013800 136 313 2.10e-61 STAT transcription factor, all-alpha
ENSTNIP00000020297 Pfam PF02864 IPR013801 315 565 1.10e-108 STAT transcription factor, DNA-binding
ENSTNIP00000020297 Pfam PF02865 IPR013799 2 121 1.30e-41 STAT transcription factor, protein interaction
ENSTNIP00000020297 Pfam PF12162 IPR022752 712 734 1.90e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
ENSTNIP00000020297 ProSiteProfiles PS50001 IPR000980 571 667 0.00e-00 SH2 domain
ENSTNIP00000020297 SMART SM00252 IPR000980 569 654 3.30e-04 SH2 domain
ENSTNIP00000020297 SMART SM00964 IPR013799 2 122 7.30e-64 STAT transcription factor, protein interaction
ENSTNIP00000020297 SUPERFAMILY SSF47655 IPR015988 137 315 0.00e-00 STAT transcription factor, coiled coil
ENSTNIP00000020297 SUPERFAMILY SSF48092 IPR013799 1 119 0.00e-00 STAT transcription factor, protein interaction
ENSTNIP00000020297 SUPERFAMILY SSF49417 IPR008967 315 566 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTNIP00000020297 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSTNIP00000020297 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSTNIP00000020297 PF02865 1.29998e-41 STAT_int STAT protein, protein interaction domain
ENSTNIP00000020297 PF12162 8.8e-13 STAT1_TAZ2bind STAT1 TAZ2 binding domain
ENSTNIP00000020297 PF00017 3.4e-10 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTNIP00000020297 GO:0001659 biological_process temperature homeostasis
ENSTNIP00000020297 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSTNIP00000020297 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSTNIP00000020297 GO:0019953 biological_process sexual reproduction
ENSTNIP00000020297 GO:0042593 biological_process glucose homeostasis
ENSTNIP00000020297 GO:0042755 biological_process eating behavior
ENSTNIP00000020297 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSTNIP00000020297 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSTNIP00000020297 GO:0005634 cellular_component nucleus
ENSTNIP00000020297 GO:0005737 cellular_component cytoplasm
ENSTNIP00000020297 GO:0005886 cellular_component plasma membrane
ENSTNIP00000020297 GO:0003677 molecular_function DNA binding
ENSTNIP00000020297 GO:0004871 molecular_function signal transducer activity
ENSTNIP00000020297 GO:0005509 molecular_function calcium ion binding
ENSTNIP00000020297 GO:0019901 molecular_function protein kinase binding
ENSTNIP00000020297 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100755609 9597 Pan paniscus 100971620
9555 Papio anubis 101005886 7897 Latimeria chalumnae 102353760
13735 Pelodiscus sinensis 102462741 10116 Rattus norvegicus 25124
9615 Canis familiaris 490967 9913 Bos taurus 510814
9646 Ailuropoda melanoleuca ENSAMEG00000014048 9358 Choloepus hoffmanni ENSCHOG00000013865
10141 Cavia porcellus ENSCPOG00000012673 7955 Danio rerio ENSDARG00000006266
9361 Dasypus novemcinctus ENSDNOG00000007325 10020 Dipodomys ordii ENSDORG00000011139
9796 Equus caballus ENSECAG00000009039 9371 Echinops telfairi ENSETEG00000017040
9685 Felis catus ENSFCAG00000013725 69293 Gasterosteus aculeatus ENSGACG00000015589
9595 Gorilla gorilla ENSGGOG00000000611 9785 Loxodonta africana ENSLAFG00000001475
9315 Macropus eugenii ENSMEUG00000012165 30608 Microcebus murinus ENSMICG00000002941
59463 Myotis lucifugus ENSMLUG00000010083 13616 Monodelphis domestica ENSMODG00000011747
61853 Nomascus leucogenys ENSNLEG00000006694 9978 Ochotona princeps ENSOPRG00000008589
9813 Procavia capensis ENSPCAG00000007855 7757 Petromyzon marinus ENSPMAG00000002770
132908 Pteropus vampyrus ENSPVAG00000004735 42254 Sorex araneus ENSSARG00000014231
9305 Sarcophilus harrisii ENSSHAG00000016913 9823 Sus scrofa ENSSSCG00000016057
43179 Ictidomys tridecemlineatus ENSSTOG00000008620 37347 Tupaia belangeri ENSTBEG00000017412
59729 Taeniopygia guttata ENSTGUG00000010768 8128 Oreochromis niloticus 100696359
39432 Saimiri boliviensis 101030811 9544 Macaca mulatta 693650
28377 Anolis carolinensis ENSACAG00000005909 9031 Gallus gallus ENSGALG00000007651
8049 Gadus morhua ENSGMOG00000012431 9103 Meleagris gallopavo ENSMGAG00000006382
9669 Mustela putorius furo ENSMPUG00000012530 9986 Oryctolagus cuniculus ENSOCUG00000002455
30611 Otolemur garnettii ENSOGAG00000003038 8090 Oryzias latipes ENSORLG00000000162
9601 Pongo abelii ENSPPYG00000013027 9598 Pan troglodytes ENSPTRG00000012749
31033 Takifugu rubripes ENSTRUG00000000102 9478 Tarsius syrichta ENSTSYG00000007651
9739 Tursiops truncatus ENSTTRG00000001134 8364 Xenopus tropicalis ENSXETG00000004649
8083 Xiphophorus maculatus ENSXMAG00000001594