Basic Information | |||
Gene ID | 693650 | ||
Gene Name | STAT1 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Macaca mulatta [9544] |
Cross Reference | |||
UniProt | F6WE02 | UniGene | Mmu.3514 |
PDB | NULL | OMIM | NULL |
KEGG | mcc:693650 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSMMUP00000007422 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 461 | 581 | 3.10e-51 | EF-hand domain pair |
ENSMMUP00000007422 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 121 | 3.70e-47 | STAT transcription factor, protein interaction |
ENSMMUP00000007422 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 137 | 317 | 1.10e-68 | STAT transcription factor, all-alpha |
ENSMMUP00000007422 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 318 | 460 | 7.40e-66 | STAT transcription factor, DNA-binding, subdomain |
ENSMMUP00000007422 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 582 | 711 | 2.00e-52 | SH2 domain |
ENSMMUP00000007422 | PANTHER | PTHR11801 | IPR001217 | 2 | 750 | 0.00e-00 | Transcription factor STAT |
ENSMMUP00000007422 | Pfam | PF00017 | IPR000980 | 578 | 638 | 7.10e-09 | SH2 domain |
ENSMMUP00000007422 | Pfam | PF01017 | IPR013800 | 137 | 315 | 1.10e-64 | STAT transcription factor, all-alpha |
ENSMMUP00000007422 | Pfam | PF02864 | IPR013801 | 317 | 567 | 4.40e-120 | STAT transcription factor, DNA-binding |
ENSMMUP00000007422 | Pfam | PF02865 | IPR013799 | 2 | 121 | 1.50e-43 | STAT transcription factor, protein interaction |
ENSMMUP00000007422 | Pfam | PF12162 | IPR022752 | 715 | 739 | 4.20e-12 | Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal |
ENSMMUP00000007422 | ProSiteProfiles | PS50001 | IPR000980 | 573 | 670 | 0.00e-00 | SH2 domain |
ENSMMUP00000007422 | SMART | SM00252 | IPR000980 | 575 | 687 | 1.60e-03 | SH2 domain |
ENSMMUP00000007422 | SMART | SM00964 | IPR013799 | 2 | 122 | 2.30e-67 | STAT transcription factor, protein interaction |
ENSMMUP00000007422 | SUPERFAMILY | SSF47655 | IPR015988 | 134 | 317 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSMMUP00000007422 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 121 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSMMUP00000007422 | SUPERFAMILY | SSF49417 | IPR008967 | 317 | 568 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSMMUP00000007422 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
ENSMMUP00000007422 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSMMUP00000007422 | PF02865 | 1.49939e-43 | STAT_int | STAT protein, protein interaction domain |
ENSMMUP00000007422 | PF12162 | 1.7e-12 | STAT1_TAZ2bind | STAT1 TAZ2 binding domain |
ENSMMUP00000007422 | PF00017 | 9.3e-10 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSMMUP00000007422 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
ENSMMUP00000007422 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
ENSMMUP00000007422 | GO:0060397 | biological_process | JAK-STAT cascade involved in growth hormone signaling pathway |
ENSMMUP00000007422 | GO:0005634 | cellular_component | nucleus |
ENSMMUP00000007422 | GO:0005737 | cellular_component | cytoplasm |
ENSMMUP00000007422 | GO:0003677 | molecular_function | DNA binding |
ENSMMUP00000007422 | GO:0004871 | molecular_function | signal transducer activity |
ENSMMUP00000007422 | GO:0005509 | molecular_function | calcium ion binding |
ENSMMUP00000007422 | GO:0019901 | molecular_function | protein kinase binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
10029 | Cricetulus griseus | 100755609 | 9597 | Pan paniscus | 100971620 |
9555 | Papio anubis | 101005886 | 7897 | Latimeria chalumnae | 102353760 |
13735 | Pelodiscus sinensis | 102462741 | 10116 | Rattus norvegicus | 25124 |
9913 | Bos taurus | 510814 | 8128 | Oreochromis niloticus | 100696359 |
39432 | Saimiri boliviensis | 101030811 | 28377 | Anolis carolinensis | ENSACAG00000005909 |
9365 | Erinaceus europaeus | ENSEEUG00000002197 | 9031 | Gallus gallus | ENSGALG00000007651 |
8049 | Gadus morhua | ENSGMOG00000012431 | 9103 | Meleagris gallopavo | ENSMGAG00000006382 |
9669 | Mustela putorius furo | ENSMPUG00000012530 | 9258 | Ornithorhynchus anatinus | ENSOANG00000022638 |
9986 | Oryctolagus cuniculus | ENSOCUG00000002455 | 30611 | Otolemur garnettii | ENSOGAG00000003038 |
8090 | Oryzias latipes | ENSORLG00000000162 | 9601 | Pongo abelii | ENSPPYG00000013027 |
9598 | Pan troglodytes | ENSPTRG00000012749 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000014048 |
9358 | Choloepus hoffmanni | ENSCHOG00000013865 | 10141 | Cavia porcellus | ENSCPOG00000012673 |
7955 | Danio rerio | ENSDARG00000006266 | 9361 | Dasypus novemcinctus | ENSDNOG00000007325 |
10020 | Dipodomys ordii | ENSDORG00000011139 | 9796 | Equus caballus | ENSECAG00000009039 |
9371 | Echinops telfairi | ENSETEG00000017040 | 9685 | Felis catus | ENSFCAG00000013725 |
69293 | Gasterosteus aculeatus | ENSGACG00000015589 | 9595 | Gorilla gorilla | ENSGGOG00000000611 |
9785 | Loxodonta africana | ENSLAFG00000001475 | 9315 | Macropus eugenii | ENSMEUG00000012165 |
30608 | Microcebus murinus | ENSMICG00000002941 | 59463 | Myotis lucifugus | ENSMLUG00000010083 |
13616 | Monodelphis domestica | ENSMODG00000011747 | 61853 | Nomascus leucogenys | ENSNLEG00000006694 |
9978 | Ochotona princeps | ENSOPRG00000008589 | 9813 | Procavia capensis | ENSPCAG00000005867 |
7757 | Petromyzon marinus | ENSPMAG00000002770 | 132908 | Pteropus vampyrus | ENSPVAG00000004735 |
9305 | Sarcophilus harrisii | ENSSHAG00000016913 | 9823 | Sus scrofa | ENSSSCG00000016057 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000008620 | 37347 | Tupaia belangeri | ENSTBEG00000017412 |
59729 | Taeniopygia guttata | ENSTGUG00000010768 | 99883 | Tetraodon nigroviridis | ENSTNIG00000017161 |
31033 | Takifugu rubripes | ENSTRUG00000000102 | 9478 | Tarsius syrichta | ENSTSYG00000007651 |
9739 | Tursiops truncatus | ENSTTRG00000001134 | 30538 | Vicugna pacos | ENSVPAG00000011543 |
8364 | Xenopus tropicalis | ENSXETG00000004649 | 8083 | Xiphophorus maculatus | ENSXMAG00000001594 |