Basic Information
Gene ID 172893
Gene Name lin-11; ZC247.3
Full Name Protein lin-11
Organism Caenorhabditis elegans [6239]

Cross Reference
UniProt P20154 UniGene Cel.18452
PDB NULL OMIM NULL
KEGG cel:CELE_ZC247.3 UCSC ZC247.3

Protein Interactions
DIP NULL
IntAct P20154
MINT NULL
STRING 6239.ZC247.3

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ZC247.3 Gene3D G3DSA:1.10.10.60 IPR009057 229 298 1.60e-23 Homeodomain-like
ZC247.3 Gene3D G3DSA:2.10.110.10 IPR001781 131 184 2.30e-13 Zinc finger, LIM-type
ZC247.3 Gene3D G3DSA:2.10.110.10 IPR001781 67 130 2.00e-14 Zinc finger, LIM-type
ZC247.3 Pfam PF00046 IPR001356 242 298 1.40e-19 Homeobox domain
ZC247.3 Pfam PF00412 IPR001781 127 184 3.00e-16 Zinc finger, LIM-type
ZC247.3 Pfam PF00412 IPR001781 68 122 4.40e-14 Zinc finger, LIM-type
ZC247.3 ProSitePatterns PS00027 IPR017970 274 297 - Homeobox, conserved site
ZC247.3 ProSitePatterns PS00478 IPR001781 127 162 - Zinc finger, LIM-type
ZC247.3 ProSitePatterns PS00478 IPR001781 68 102 - Zinc finger, LIM-type
ZC247.3 ProSiteProfiles PS50023 IPR001781 126 188 0.00e-00 Zinc finger, LIM-type
ZC247.3 ProSiteProfiles PS50023 IPR001781 66 125 0.00e-00 Zinc finger, LIM-type
ZC247.3 ProSiteProfiles PS50071 IPR001356 239 299 0.00e-00 Homeobox domain
ZC247.3 SMART SM00132 IPR001781 126 181 1.10e-17 Zinc finger, LIM-type
ZC247.3 SMART SM00132 IPR001781 67 118 5.10e-17 Zinc finger, LIM-type
ZC247.3 SMART SM00389 IPR001356 241 303 1.80e-24 Homeobox domain
ZC247.3 SUPERFAMILY SSF46689 IPR009057 234 302 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ZC247.3 PF00412 7.2e-31 LIM LIM domain
ZC247.3 PF00046 6.3e-20 Homeobox Homeobox domain
ZC247.3 PF05920 1.6e-05 Homeobox_KN Homeobox KN domain

Gene Ontology Annotation
Protein Entry Name Space Description
ZC247.3 GO:0001655 biological_process urogenital system development
ZC247.3 GO:0001657 biological_process ureteric bud development
ZC247.3 GO:0001702 biological_process gastrulation with mouth forming second
ZC247.3 GO:0001705 biological_process ectoderm formation
ZC247.3 GO:0001706 biological_process endoderm formation
ZC247.3 GO:0001822 biological_process kidney development
ZC247.3 GO:0006366 biological_process transcription from RNA polymerase II promoter
ZC247.3 GO:0007267 biological_process cell-cell signaling
ZC247.3 GO:0007389 biological_process pattern specification process
ZC247.3 GO:0007399 biological_process nervous system development
ZC247.3 GO:0008045 biological_process motor neuron axon guidance
ZC247.3 GO:0009653 biological_process anatomical structure morphogenesis
ZC247.3 GO:0009791 biological_process post-embryonic development
ZC247.3 GO:0009880 biological_process embryonic pattern specification
ZC247.3 GO:0009948 biological_process anterior/posterior axis specification
ZC247.3 GO:0009952 biological_process anterior/posterior pattern specification
ZC247.3 GO:0009953 biological_process dorsal/ventral pattern formation
ZC247.3 GO:0010468 biological_process regulation of gene expression
ZC247.3 GO:0010842 biological_process retina layer formation
ZC247.3 GO:0021527 biological_process spinal cord association neuron differentiation
ZC247.3 GO:0021549 biological_process cerebellum development
ZC247.3 GO:0021702 biological_process cerebellar Purkinje cell differentiation
ZC247.3 GO:0021871 biological_process forebrain regionalization
ZC247.3 GO:0021937 biological_process cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
ZC247.3 GO:0035846 biological_process oviduct epithelium development
ZC247.3 GO:0035847 biological_process uterine epithelium development
ZC247.3 GO:0040019 biological_process positive regulation of embryonic development
ZC247.3 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ZC247.3 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ZC247.3 GO:0048646 biological_process anatomical structure formation involved in morphogenesis
ZC247.3 GO:0048703 biological_process embryonic viscerocranium morphogenesis
ZC247.3 GO:0060059 biological_process embryonic retina morphogenesis in camera-type eye
ZC247.3 GO:0060067 biological_process cervix development
ZC247.3 GO:0060068 biological_process vagina development
ZC247.3 GO:0060322 biological_process head development
ZC247.3 GO:0060429 biological_process epithelium development
ZC247.3 GO:0061205 biological_process paramesonephric duct development
ZC247.3 GO:0072049 biological_process comma-shaped body morphogenesis
ZC247.3 GO:0072050 biological_process S-shaped body morphogenesis
ZC247.3 GO:0072077 biological_process renal vesicle morphogenesis
ZC247.3 GO:0072178 biological_process nephric duct morphogenesis
ZC247.3 GO:0090009 biological_process primitive streak formation
ZC247.3 GO:0090190 biological_process positive regulation of branching involved in ureteric bud morphogenesis
ZC247.3 GO:0097477 biological_process lateral motor column neuron migration
ZC247.3 GO:2000543 biological_process positive regulation of gastrulation
ZC247.3 GO:2000744 biological_process positive regulation of anterior head development
ZC247.3 GO:2000768 biological_process positive regulation of nephron tubule epithelial cell differentiation
ZC247.3 GO:0005634 cellular_component nucleus
ZC247.3 GO:0043234 cellular_component protein complex
ZC247.3 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ZC247.3 GO:0003714 molecular_function transcription corepressor activity
ZC247.3 GO:0008270 molecular_function zinc ion binding
ZC247.3 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116733 9601 Pongo abelii 100451412
34638 Metaseiulus occidentalis 100904816 30611 Otolemur garnettii 100951554
9597 Pan paniscus 100988029 9555 Papio anubis 101008593
8083 Xiphophorus maculatus 102218401 13616 Monodelphis domestica 100028420
7029 Acyrthosiphon pisum 100158984 9483 Callithrix jacchus 100392549
9823 Sus scrofa 100513681 30195 Bombus terrestris 100644955
9785 Loxodonta africana 100675956 10029 Cricetulus griseus 100758453
9615 Canis familiaris 100856649 9305 Sarcophilus harrisii 100931234
39432 Saimiri boliviensis 101033157 31033 Takifugu rubripes 101061689
9685 Felis catus 101083467 9595 Gorilla gorilla 101135759
8090 Oryzias latipes 101166400 9669 Mustela putorius furo 101687390
43179 Ictidomys tridecemlineatus 101973608 7897 Latimeria chalumnae 102362985
59463 Myotis lucifugus 102440821 13735 Pelodiscus sinensis 102453882
10116 Rattus norvegicus 257634 7955 Danio rerio 30465
7227 Drosophila melanogaster 31813 7668 Strongylocentrotus purpuratus 373522
8364 Xenopus tropicalis 548836 9606 Homo sapiens 64211
7070 Tribolium castaneum 657972 9913 Bos taurus 786041
9358 Choloepus hoffmanni ENSCHOG00000007567 10141 Cavia porcellus ENSCPOG00000023977
9361 Dasypus novemcinctus ENSDNOG00000010448 9796 Equus caballus ENSECAG00000016915
9365 Erinaceus europaeus ENSEEUG00000002834 9371 Echinops telfairi ENSETEG00000003513
69293 Gasterosteus aculeatus ENSGACG00000013605 9031 Gallus gallus ENSGALG00000005409
9544 Macaca mulatta ENSMMUG00000021668 61853 Nomascus leucogenys ENSNLEG00000002343
9258 Ornithorhynchus anatinus ENSOANG00000014248 9986 Oryctolagus cuniculus ENSOCUG00000024664
9813 Procavia capensis ENSPCAG00000010694 132908 Pteropus vampyrus ENSPVAG00000015637
37347 Tupaia belangeri ENSTBEG00000007734 59729 Taeniopygia guttata ENSTGUG00000008052
99883 Tetraodon nigroviridis ENSTNIG00000013489 9739 Tursiops truncatus ENSTTRG00000008900
28377 Anolis carolinensis ENSACAG00000005037 9646 Ailuropoda melanoleuca ENSAMEG00000008305
10020 Dipodomys ordii ENSDORG00000006956 8049 Gadus morhua ENSGMOG00000002984
9315 Macropus eugenii ENSMEUG00000006658 9598 Pan troglodytes ENSPTRG00000009050
42254 Sorex araneus ENSSARG00000010593 9478 Tarsius syrichta ENSTSYG00000001931