Basic Information
Gene ID 18424 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Otx2
Full Name Homeobox protein OTX2
Organism Mus musculus [10090]

Cross Reference
UniProt Q8R0B5 UniGene Mm.487292
PDB NULL OMIM NULL
KEGG NULL UCSC uc007tjs.2

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 10090.ENSMUSP00000051021

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000112532 Gene3D G3DSA:1.10.10.60 IPR009057 42 110 8.30e-27 Homeodomain-like
ENSMUSP00000112532 Pfam PF00046 IPR001356 47 103 8.70e-22 Homeobox domain
ENSMUSP00000112532 Pfam PF03529 IPR013851 161 243 3.70e-37 Transcription factor Otx, C-terminal
ENSMUSP00000112532 PRINTS PR01255 IPR003025 1 10 6.90e-13 Transcription factor Otx
ENSMUSP00000112532 PRINTS PR01255 IPR003025 183 189 6.90e-13 Transcription factor Otx
ENSMUSP00000112532 PRINTS PR01255 IPR003025 203 211 6.90e-13 Transcription factor Otx
ENSMUSP00000112532 PRINTS PR01255 IPR003025 263 269 6.90e-13 Transcription factor Otx
ENSMUSP00000112532 PRINTS PR01257 IPR003022 15 21 3.50e-14 Transcription factor Otx2
ENSMUSP00000112532 PRINTS PR01257 IPR003022 167 176 3.50e-14 Transcription factor Otx2
ENSMUSP00000112532 PRINTS PR01257 IPR003022 186 192 3.50e-14 Transcription factor Otx2
ENSMUSP00000112532 PRINTS PR01257 IPR003022 238 247 3.50e-14 Transcription factor Otx2
ENSMUSP00000112532 ProSitePatterns PS00027 IPR017970 79 102 - Homeobox, conserved site
ENSMUSP00000112532 ProSiteProfiles PS50071 IPR001356 44 104 0.00e-00 Homeobox domain
ENSMUSP00000112532 SMART SM00389 IPR001356 46 108 4.00e-27 Homeobox domain
ENSMUSP00000112532 SUPERFAMILY SSF46689 IPR009057 29 106 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000112532 PF03529 3.7e-37 TF_Otx Otx1 transcription factor
ENSMUSP00000112532 PF00046 5.6e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000112532 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMUSP00000112532 GO:0007275 biological_process multicellular organismal development
ENSMUSP00000112532 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMUSP00000112532 GO:0005634 cellular_component nucleus
ENSMUSP00000112532 GO:0003677 molecular_function DNA binding
ENSMUSP00000112532 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000112532 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100302712 9785 Loxodonta africana 100666163
8128 Oreochromis niloticus 100707476 132113 Bombus impatiens 100746189
7463 Apis florea 100864069 143995 Megachile rotundata 100877036
39432 Saimiri boliviensis 101029683 9595 Gorilla gorilla 101135739
9669 Mustela putorius furo 101677421 9986 Oryctolagus cuniculus 100009374
9796 Equus caballus 100050678 7425 Nasonia vitripennis 100118780
9646 Ailuropoda melanoleuca 100467291 30195 Bombus terrestris 100646401
34638 Metaseiulus occidentalis 100905820 9597 Pan paniscus 100983632
9555 Papio anubis 101007811 43179 Ictidomys tridecemlineatus 101960358
8083 Xiphophorus maculatus 102228797 13735 Pelodiscus sinensis 102450003
6239 Caenorhabditis elegans 181530 7955 Danio rerio 30501
9031 Gallus gallus 395191 7719 Ciona intestinalis 445669
9606 Homo sapiens 5015 9358 Choloepus hoffmanni ENSCHOG00000013827
9483 Callithrix jacchus ENSCJAG00000018583 10141 Cavia porcellus ENSCPOG00000003420
51511 Ciona savignyi ENSCSAVG00000009682 9371 Echinops telfairi ENSETEG00000014047
69293 Gasterosteus aculeatus ENSGACG00000012744 8049 Gadus morhua ENSGMOG00000016352
7897 Latimeria chalumnae ENSLACG00000018973 9315 Macropus eugenii ENSMEUG00000000827
30608 Microcebus murinus ENSMICG00000017005 61853 Nomascus leucogenys ENSNLEG00000012999
30611 Otolemur garnettii ENSOGAG00000006981 8090 Oryzias latipes ENSORLG00000016191
9813 Procavia capensis ENSPCAG00000009289 42254 Sorex araneus ENSSARG00000007709
37347 Tupaia belangeri ENSTBEG00000002550 99883 Tetraodon nigroviridis ENSTNIG00000017380
31033 Takifugu rubripes ENSTRUG00000018137 9739 Tursiops truncatus ENSTTRG00000004650
8364 Xenopus tropicalis ENSXETG00000018775 9913 Bos taurus 280756
7668 Strongylocentrotus purpuratus 373400 28377 Anolis carolinensis ENSACAG00000008544
10020 Dipodomys ordii ENSDORG00000002219 9365 Erinaceus europaeus ENSEEUG00000015763
9685 Felis catus ENSFCAG00000024521 9103 Meleagris gallopavo ENSMGAG00000013637
59463 Myotis lucifugus ENSMLUG00000022591 9544 Macaca mulatta ENSMMUG00000002425
9978 Ochotona princeps ENSOPRG00000015946 7757 Petromyzon marinus ENSPMAG00000001190
9601 Pongo abelii ENSPPYG00000005846 132908 Pteropus vampyrus ENSPVAG00000001624
59729 Taeniopygia guttata ENSTGUG00000013055 9478 Tarsius syrichta ENSTSYG00000006803
30538 Vicugna pacos ENSVPAG00000002702