Basic Information
Gene ID 395191
Gene Name OTX2
Full Name Homeodomain transcription factor
Organism Gallus gallus [9031]

Cross Reference
UniProt Q6E236 UniGene Gga.10
PDB NULL OMIM NULL
KEGG gga:395191 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9031.ENSGALP00000031824

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGALP00000042928 Gene3D G3DSA:1.10.10.60 IPR009057 34 102 7.00e-27 Homeodomain-like
ENSGALP00000042928 Pfam PF00046 IPR001356 39 95 8.30e-22 Homeobox domain
ENSGALP00000042928 Pfam PF03529 IPR013851 153 235 2.40e-37 Transcription factor Otx, C-terminal
ENSGALP00000042928 PRINTS PR01255 IPR003025 1 10 6.30e-13 Transcription factor Otx
ENSGALP00000042928 PRINTS PR01255 IPR003025 175 181 6.30e-13 Transcription factor Otx
ENSGALP00000042928 PRINTS PR01255 IPR003025 195 203 6.30e-13 Transcription factor Otx
ENSGALP00000042928 PRINTS PR01255 IPR003025 255 261 6.30e-13 Transcription factor Otx
ENSGALP00000042928 PRINTS PR01257 IPR003022 15 21 3.20e-14 Transcription factor Otx2
ENSGALP00000042928 PRINTS PR01257 IPR003022 159 168 3.20e-14 Transcription factor Otx2
ENSGALP00000042928 PRINTS PR01257 IPR003022 178 184 3.20e-14 Transcription factor Otx2
ENSGALP00000042928 PRINTS PR01257 IPR003022 230 239 3.20e-14 Transcription factor Otx2
ENSGALP00000042928 ProSitePatterns PS00027 IPR017970 71 94 - Homeobox, conserved site
ENSGALP00000042928 ProSiteProfiles PS50071 IPR001356 36 96 0.00e-00 Homeobox domain
ENSGALP00000042928 SMART SM00389 IPR001356 38 100 4.00e-27 Homeobox domain
ENSGALP00000042928 SUPERFAMILY SSF46689 IPR009057 16 98 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGALP00000042928 PF03529 2.4e-37 TF_Otx Otx1 transcription factor
ENSGALP00000042928 PF00046 5.3e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGALP00000042928 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSGALP00000042928 GO:0007275 biological_process multicellular organismal development
ENSGALP00000042928 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSGALP00000042928 GO:0005634 cellular_component nucleus
ENSGALP00000042928 GO:0003677 molecular_function DNA binding
ENSGALP00000042928 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSGALP00000042928 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100009374 9796 Equus caballus 100050678
7425 Nasonia vitripennis 100118780 7029 Acyrthosiphon pisum 100169486
6087 Hydra magnipapillata 100209084 10224 Saccoglossus kowalevskii 100302712
9646 Ailuropoda melanoleuca 100467291 30195 Bombus terrestris 100646401
9785 Loxodonta africana 100666163 8128 Oreochromis niloticus 100707476
132113 Bombus impatiens 100746189 10029 Cricetulus griseus 100764947
7463 Apis florea 100864069 143995 Megachile rotundata 100877036
9305 Sarcophilus harrisii 100925398 9597 Pan paniscus 100983632
9555 Papio anubis 101007811 39432 Saimiri boliviensis 101029683
9595 Gorilla gorilla 101135739 9669 Mustela putorius furo 101677421
43179 Ictidomys tridecemlineatus 101960358 8083 Xiphophorus maculatus 102228797
13735 Pelodiscus sinensis 102450003 6239 Caenorhabditis elegans 181530
10090 Mus musculus 18424 9913 Bos taurus 280756
7955 Danio rerio 30501 7227 Drosophila melanogaster 31802
7668 Strongylocentrotus purpuratus 373400 34638 Metaseiulus occidentalis 100905820
51511 Ciona savignyi ENSCSAVG00000009682 7719 Ciona intestinalis 445669
9606 Homo sapiens 5015 9615 Canis familiaris 610347
7070 Tribolium castaneum 641604 9598 Pan troglodytes 744025
28377 Anolis carolinensis ENSACAG00000008544 9358 Choloepus hoffmanni ENSCHOG00000013827
9483 Callithrix jacchus ENSCJAG00000018583 10141 Cavia porcellus ENSCPOG00000003420
10020 Dipodomys ordii ENSDORG00000002219 9365 Erinaceus europaeus ENSEEUG00000015763
9371 Echinops telfairi ENSETEG00000014047 9685 Felis catus ENSFCAG00000024521
69293 Gasterosteus aculeatus ENSGACG00000012744 8049 Gadus morhua ENSGMOG00000016352
7897 Latimeria chalumnae ENSLACG00000018973 9315 Macropus eugenii ENSMEUG00000000827
9103 Meleagris gallopavo ENSMGAG00000013637 30608 Microcebus murinus ENSMICG00000017005
59463 Myotis lucifugus ENSMLUG00000022591 9544 Macaca mulatta ENSMMUG00000002425
13616 Monodelphis domestica ENSMODG00000003035 61853 Nomascus leucogenys ENSNLEG00000012999
30611 Otolemur garnettii ENSOGAG00000006981 9978 Ochotona princeps ENSOPRG00000015946
8090 Oryzias latipes ENSORLG00000016191 9813 Procavia capensis ENSPCAG00000009289
7757 Petromyzon marinus ENSPMAG00000001190 9601 Pongo abelii ENSPPYG00000005846
132908 Pteropus vampyrus ENSPVAG00000001624 10116 Rattus norvegicus ENSRNOG00000008756
42254 Sorex araneus ENSSARG00000007709 37347 Tupaia belangeri ENSTBEG00000002550
59729 Taeniopygia guttata ENSTGUG00000013055 99883 Tetraodon nigroviridis ENSTNIG00000017380
31033 Takifugu rubripes ENSTRUG00000018137 9478 Tarsius syrichta ENSTSYG00000006803
9739 Tursiops truncatus ENSTTRG00000004650 30538 Vicugna pacos ENSVPAG00000002702
8364 Xenopus tropicalis ENSXETG00000018775