Basic Information
Gene ID ENSMEUG00000000827
Gene Name Otx2
Full Name Transcription factor Otx2
Organism Macropus eugenii [9315]

Cross Reference
UniProt Q6VN45 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMEUP00000000765 Gene3D G3DSA:1.10.10.60 IPR009057 8 76 1.20e-26 Homeodomain-like
ENSMEUP00000000765 Pfam PF00046 IPR001356 13 69 7.10e-22 Homeobox domain
ENSMEUP00000000765 Pfam PF03529 IPR013851 127 208 3.70e-37 Transcription factor Otx, C-terminal
ENSMEUP00000000765 PRINTS PR01255 IPR003025 149 155 1.20e-06 Transcription factor Otx
ENSMEUP00000000765 PRINTS PR01255 IPR003025 169 177 1.20e-06 Transcription factor Otx
ENSMEUP00000000765 PRINTS PR01255 IPR003025 229 235 1.20e-06 Transcription factor Otx
ENSMEUP00000000765 PRINTS PR01257 IPR003022 133 142 2.60e-08 Transcription factor Otx2
ENSMEUP00000000765 PRINTS PR01257 IPR003022 152 158 2.60e-08 Transcription factor Otx2
ENSMEUP00000000765 PRINTS PR01257 IPR003022 204 213 2.60e-08 Transcription factor Otx2
ENSMEUP00000000765 ProSitePatterns PS00027 IPR017970 45 68 - Homeobox, conserved site
ENSMEUP00000000765 ProSiteProfiles PS50071 IPR001356 10 70 0.00e-00 Homeobox domain
ENSMEUP00000000765 SMART SM00389 IPR001356 12 74 4.00e-27 Homeobox domain
ENSMEUP00000000765 SUPERFAMILY SSF46689 IPR009057 5 75 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMEUP00000000765 PF03529 3.7e-37 TF_Otx Otx1 transcription factor
ENSMEUP00000000765 PF00046 4.6e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMEUP00000000765 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMEUP00000000765 GO:0007275 biological_process multicellular organismal development
ENSMEUP00000000765 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMEUP00000000765 GO:0005634 cellular_component nucleus
ENSMEUP00000000765 GO:0003677 molecular_function DNA binding
ENSMEUP00000000765 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMEUP00000000765 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100009374 9796 Equus caballus 100050678
7029 Acyrthosiphon pisum 100169486 6087 Hydra magnipapillata 100209084
10224 Saccoglossus kowalevskii 100302712 9646 Ailuropoda melanoleuca 100467291
30195 Bombus terrestris 100646401 9785 Loxodonta africana 100666163
8128 Oreochromis niloticus 100707476 132113 Bombus impatiens 100746189
10029 Cricetulus griseus 100764947 7463 Apis florea 100864069
143995 Megachile rotundata 100877036 9305 Sarcophilus harrisii 100925398
9597 Pan paniscus 100983632 9555 Papio anubis 101007811
39432 Saimiri boliviensis 101029683 9595 Gorilla gorilla 101135739
9669 Mustela putorius furo 101677421 43179 Ictidomys tridecemlineatus 101960358
8083 Xiphophorus maculatus 102228797 13735 Pelodiscus sinensis 102450003
6239 Caenorhabditis elegans 181530 10090 Mus musculus 18424
7955 Danio rerio 30501 7227 Drosophila melanogaster 31802
7668 Strongylocentrotus purpuratus 373400 7719 Ciona intestinalis 445669
9606 Homo sapiens 5015 9615 Canis familiaris 610347
7070 Tribolium castaneum 641604 9598 Pan troglodytes 744025
28377 Anolis carolinensis ENSACAG00000008544 9358 Choloepus hoffmanni ENSCHOG00000013827
9483 Callithrix jacchus ENSCJAG00000018583 10141 Cavia porcellus ENSCPOG00000003420
10020 Dipodomys ordii ENSDORG00000002219 9365 Erinaceus europaeus ENSEEUG00000015763
9371 Echinops telfairi ENSETEG00000014047 9685 Felis catus ENSFCAG00000024521
69293 Gasterosteus aculeatus ENSGACG00000012744 8049 Gadus morhua ENSGMOG00000016352
7897 Latimeria chalumnae ENSLACG00000018973 7425 Nasonia vitripennis 100118780
34638 Metaseiulus occidentalis 100905820 9031 Gallus gallus 395191
51511 Ciona savignyi ENSCSAVG00000009682 9739 Tursiops truncatus ENSTTRG00000004650
9103 Meleagris gallopavo ENSMGAG00000013637 30608 Microcebus murinus ENSMICG00000017005
59463 Myotis lucifugus ENSMLUG00000022591 9544 Macaca mulatta ENSMMUG00000002425
61853 Nomascus leucogenys ENSNLEG00000012999 30611 Otolemur garnettii ENSOGAG00000006981
9978 Ochotona princeps ENSOPRG00000015946 8090 Oryzias latipes ENSORLG00000016191
9813 Procavia capensis ENSPCAG00000009289 7757 Petromyzon marinus ENSPMAG00000001190
9601 Pongo abelii ENSPPYG00000005846 132908 Pteropus vampyrus ENSPVAG00000001624
10116 Rattus norvegicus ENSRNOG00000008756 42254 Sorex araneus ENSSARG00000007709
37347 Tupaia belangeri ENSTBEG00000002550 59729 Taeniopygia guttata ENSTGUG00000013055
99883 Tetraodon nigroviridis ENSTNIG00000017380 31033 Takifugu rubripes ENSTRUG00000018137
9478 Tarsius syrichta ENSTSYG00000006803 30538 Vicugna pacos ENSVPAG00000002702
8364 Xenopus tropicalis ENSXETG00000018775