Basic Information | |||
Gene ID | 5015 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | OTX2 | ||
Full Name | Homeobox protein OTX2 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P32243 | UniGene | Hs.741558 |
PDB | NULL | OMIM | 613986 |
KEGG | hsa:5015 | UCSC | uc001xcp.4 |
Protein Interactions | |
DIP | NULL |
IntAct | P32243 |
MINT | MINT-2861458 |
STRING | 9606.ENSP00000343819 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000343819 | Gene3D | G3DSA:1.10.10.60 | IPR009057 | 42 | 110 | 8.30e-27 | Homeodomain-like |
ENSP00000343819 | Pfam | PF00046 | IPR001356 | 47 | 103 | 8.70e-22 | Homeobox domain |
ENSP00000343819 | Pfam | PF03529 | IPR013851 | 161 | 243 | 3.70e-37 | Transcription factor Otx, C-terminal |
ENSP00000343819 | PRINTS | PR01255 | IPR003025 | 1 | 10 | 6.90e-13 | Transcription factor Otx |
ENSP00000343819 | PRINTS | PR01255 | IPR003025 | 183 | 189 | 6.90e-13 | Transcription factor Otx |
ENSP00000343819 | PRINTS | PR01255 | IPR003025 | 203 | 211 | 6.90e-13 | Transcription factor Otx |
ENSP00000343819 | PRINTS | PR01255 | IPR003025 | 263 | 269 | 6.90e-13 | Transcription factor Otx |
ENSP00000343819 | PRINTS | PR01257 | IPR003022 | 15 | 21 | 3.50e-14 | Transcription factor Otx2 |
ENSP00000343819 | PRINTS | PR01257 | IPR003022 | 167 | 176 | 3.50e-14 | Transcription factor Otx2 |
ENSP00000343819 | PRINTS | PR01257 | IPR003022 | 186 | 192 | 3.50e-14 | Transcription factor Otx2 |
ENSP00000343819 | PRINTS | PR01257 | IPR003022 | 238 | 247 | 3.50e-14 | Transcription factor Otx2 |
ENSP00000343819 | ProSitePatterns | PS00027 | IPR017970 | 79 | 102 | - | Homeobox, conserved site |
ENSP00000343819 | ProSiteProfiles | PS50071 | IPR001356 | 44 | 104 | 0.00e-00 | Homeobox domain |
ENSP00000343819 | SMART | SM00389 | IPR001356 | 46 | 108 | 4.00e-27 | Homeobox domain |
ENSP00000343819 | SUPERFAMILY | SSF46689 | IPR009057 | 29 | 106 | 0.00e-00 | Homeodomain-like |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000343819 | PF03529 | 3.7e-37 | TF_Otx | Otx1 transcription factor |
ENSP00000343819 | PF00046 | 5.6e-22 | Homeobox | Homeobox domain |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
6087 | Hydra magnipapillata | 100209084 | 10224 | Saccoglossus kowalevskii | 100302712 |
9785 | Loxodonta africana | 100666163 | 8128 | Oreochromis niloticus | 100707476 |
132113 | Bombus impatiens | 100746189 | 10029 | Cricetulus griseus | 100764947 |
7463 | Apis florea | 100864069 | 143995 | Megachile rotundata | 100877036 |
39432 | Saimiri boliviensis | 101029683 | 9595 | Gorilla gorilla | 101135739 |
9669 | Mustela putorius furo | 101677421 | 10090 | Mus musculus | 18424 |
9913 | Bos taurus | 280756 | 7955 | Danio rerio | 30501 |
7227 | Drosophila melanogaster | 31802 | 7668 | Strongylocentrotus purpuratus | 373400 |
9986 | Oryctolagus cuniculus | 100009374 | 9796 | Equus caballus | 100050678 |
7425 | Nasonia vitripennis | 100118780 | 7029 | Acyrthosiphon pisum | 100169486 |
9646 | Ailuropoda melanoleuca | 100467291 | 30195 | Bombus terrestris | 100646401 |
34638 | Metaseiulus occidentalis | 100905820 | 9305 | Sarcophilus harrisii | 100925398 |
9597 | Pan paniscus | 100983632 | 9555 | Papio anubis | 101007811 |
43179 | Ictidomys tridecemlineatus | 101960358 | 8083 | Xiphophorus maculatus | 102228797 |
13735 | Pelodiscus sinensis | 102450003 | 6239 | Caenorhabditis elegans | 181530 |
9031 | Gallus gallus | 395191 | 7719 | Ciona intestinalis | 445669 |
7070 | Tribolium castaneum | 641604 | 9358 | Choloepus hoffmanni | ENSCHOG00000013827 |
10141 | Cavia porcellus | ENSCPOG00000003420 | 51511 | Ciona savignyi | ENSCSAVG00000009682 |
9371 | Echinops telfairi | ENSETEG00000014047 | 8049 | Gadus morhua | ENSGMOG00000016352 |
7897 | Latimeria chalumnae | ENSLACG00000018973 | 9315 | Macropus eugenii | ENSMEUG00000000827 |
30608 | Microcebus murinus | ENSMICG00000017005 | 61853 | Nomascus leucogenys | ENSNLEG00000012999 |
30611 | Otolemur garnettii | ENSOGAG00000006981 | 8090 | Oryzias latipes | ENSORLG00000016191 |
9813 | Procavia capensis | ENSPCAG00000009289 | 42254 | Sorex araneus | ENSSARG00000007709 |
37347 | Tupaia belangeri | ENSTBEG00000002550 | 99883 | Tetraodon nigroviridis | ENSTNIG00000017380 |
31033 | Takifugu rubripes | ENSTRUG00000018137 | 9739 | Tursiops truncatus | ENSTTRG00000004650 |
8364 | Xenopus tropicalis | ENSXETG00000018775 | 9615 | Canis familiaris | 610347 |
9598 | Pan troglodytes | 744025 | 28377 | Anolis carolinensis | ENSACAG00000008544 |
9483 | Callithrix jacchus | ENSCJAG00000018583 | 10020 | Dipodomys ordii | ENSDORG00000002219 |
9365 | Erinaceus europaeus | ENSEEUG00000015763 | 9685 | Felis catus | ENSFCAG00000024521 |
69293 | Gasterosteus aculeatus | ENSGACG00000012744 | 9103 | Meleagris gallopavo | ENSMGAG00000013637 |
59463 | Myotis lucifugus | ENSMLUG00000022591 | 9544 | Macaca mulatta | ENSMMUG00000002425 |
13616 | Monodelphis domestica | ENSMODG00000003035 | 9978 | Ochotona princeps | ENSOPRG00000015946 |
7757 | Petromyzon marinus | ENSPMAG00000001190 | 9601 | Pongo abelii | ENSPPYG00000005846 |
132908 | Pteropus vampyrus | ENSPVAG00000001624 | 10116 | Rattus norvegicus | ENSRNOG00000008756 |
59729 | Taeniopygia guttata | ENSTGUG00000013055 | 9478 | Tarsius syrichta | ENSTSYG00000006803 |
30538 | Vicugna pacos | ENSVPAG00000002702 |