Basic Information
Gene ID 5015 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name OTX2
Full Name Homeobox protein OTX2
Organism Homo sapiens [9606]

Cross Reference
UniProt P32243 UniGene Hs.741558
PDB NULL OMIM 613986
KEGG hsa:5015 UCSC uc001xcp.4

Protein Interactions
DIP NULL
IntAct P32243
MINT MINT-2861458
STRING 9606.ENSP00000343819

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000343819 Gene3D G3DSA:1.10.10.60 IPR009057 42 110 8.30e-27 Homeodomain-like
ENSP00000343819 Pfam PF00046 IPR001356 47 103 8.70e-22 Homeobox domain
ENSP00000343819 Pfam PF03529 IPR013851 161 243 3.70e-37 Transcription factor Otx, C-terminal
ENSP00000343819 PRINTS PR01255 IPR003025 1 10 6.90e-13 Transcription factor Otx
ENSP00000343819 PRINTS PR01255 IPR003025 183 189 6.90e-13 Transcription factor Otx
ENSP00000343819 PRINTS PR01255 IPR003025 203 211 6.90e-13 Transcription factor Otx
ENSP00000343819 PRINTS PR01255 IPR003025 263 269 6.90e-13 Transcription factor Otx
ENSP00000343819 PRINTS PR01257 IPR003022 15 21 3.50e-14 Transcription factor Otx2
ENSP00000343819 PRINTS PR01257 IPR003022 167 176 3.50e-14 Transcription factor Otx2
ENSP00000343819 PRINTS PR01257 IPR003022 186 192 3.50e-14 Transcription factor Otx2
ENSP00000343819 PRINTS PR01257 IPR003022 238 247 3.50e-14 Transcription factor Otx2
ENSP00000343819 ProSitePatterns PS00027 IPR017970 79 102 - Homeobox, conserved site
ENSP00000343819 ProSiteProfiles PS50071 IPR001356 44 104 0.00e-00 Homeobox domain
ENSP00000343819 SMART SM00389 IPR001356 46 108 4.00e-27 Homeobox domain
ENSP00000343819 SUPERFAMILY SSF46689 IPR009057 29 106 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000343819 PF03529 3.7e-37 TF_Otx Otx1 transcription factor
ENSP00000343819 PF00046 5.6e-22 Homeobox Homeobox domain

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
6087 Hydra magnipapillata 100209084 10224 Saccoglossus kowalevskii 100302712
9785 Loxodonta africana 100666163 8128 Oreochromis niloticus 100707476
132113 Bombus impatiens 100746189 10029 Cricetulus griseus 100764947
7463 Apis florea 100864069 143995 Megachile rotundata 100877036
39432 Saimiri boliviensis 101029683 9595 Gorilla gorilla 101135739
9669 Mustela putorius furo 101677421 10090 Mus musculus 18424
9913 Bos taurus 280756 7955 Danio rerio 30501
7227 Drosophila melanogaster 31802 7668 Strongylocentrotus purpuratus 373400
9986 Oryctolagus cuniculus 100009374 9796 Equus caballus 100050678
7425 Nasonia vitripennis 100118780 7029 Acyrthosiphon pisum 100169486
9646 Ailuropoda melanoleuca 100467291 30195 Bombus terrestris 100646401
34638 Metaseiulus occidentalis 100905820 9305 Sarcophilus harrisii 100925398
9597 Pan paniscus 100983632 9555 Papio anubis 101007811
43179 Ictidomys tridecemlineatus 101960358 8083 Xiphophorus maculatus 102228797
13735 Pelodiscus sinensis 102450003 6239 Caenorhabditis elegans 181530
9031 Gallus gallus 395191 7719 Ciona intestinalis 445669
7070 Tribolium castaneum 641604 9358 Choloepus hoffmanni ENSCHOG00000013827
10141 Cavia porcellus ENSCPOG00000003420 51511 Ciona savignyi ENSCSAVG00000009682
9371 Echinops telfairi ENSETEG00000014047 8049 Gadus morhua ENSGMOG00000016352
7897 Latimeria chalumnae ENSLACG00000018973 9315 Macropus eugenii ENSMEUG00000000827
30608 Microcebus murinus ENSMICG00000017005 61853 Nomascus leucogenys ENSNLEG00000012999
30611 Otolemur garnettii ENSOGAG00000006981 8090 Oryzias latipes ENSORLG00000016191
9813 Procavia capensis ENSPCAG00000009289 42254 Sorex araneus ENSSARG00000007709
37347 Tupaia belangeri ENSTBEG00000002550 99883 Tetraodon nigroviridis ENSTNIG00000017380
31033 Takifugu rubripes ENSTRUG00000018137 9739 Tursiops truncatus ENSTTRG00000004650
8364 Xenopus tropicalis ENSXETG00000018775 9615 Canis familiaris 610347
9598 Pan troglodytes 744025 28377 Anolis carolinensis ENSACAG00000008544
9483 Callithrix jacchus ENSCJAG00000018583 10020 Dipodomys ordii ENSDORG00000002219
9365 Erinaceus europaeus ENSEEUG00000015763 9685 Felis catus ENSFCAG00000024521
69293 Gasterosteus aculeatus ENSGACG00000012744 9103 Meleagris gallopavo ENSMGAG00000013637
59463 Myotis lucifugus ENSMLUG00000022591 9544 Macaca mulatta ENSMMUG00000002425
13616 Monodelphis domestica ENSMODG00000003035 9978 Ochotona princeps ENSOPRG00000015946
7757 Petromyzon marinus ENSPMAG00000001190 9601 Pongo abelii ENSPPYG00000005846
132908 Pteropus vampyrus ENSPVAG00000001624 10116 Rattus norvegicus ENSRNOG00000008756
59729 Taeniopygia guttata ENSTGUG00000013055 9478 Tarsius syrichta ENSTSYG00000006803
30538 Vicugna pacos ENSVPAG00000002702