Basic Information
Gene ID 414294
Gene Name Hes
Full Name Hairy/enhancer of split
Organism Strongylocentrotus purpuratus [7668]

Cross Reference
UniProt Q6JJ70 UniGene Spu.2621
PDB NULL OMIM NULL
KEGG spu:414294 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7668.Q6JJ70

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003726300 Gene3D G3DSA:4.10.280.10 IPR011598 25 84 3.70e-13 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003726300 Pfam PF00010 IPR011598 25 82 2.20e-13 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003726300 Pfam PF07527 IPR003650 98 141 3.90e-13 Orange
XP_003726300 ProSiteProfiles PS50888 IPR011598 24 81 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003726300 ProSiteProfiles PS51054 IPR003650 100 134 0.00e-00 Orange
XP_003726300 SMART SM00353 IPR011598 30 87 1.10e-13 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003726300 SUPERFAMILY SSF47459 IPR011598 23 83 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003726300 PF00010 1.2e-13 HLH Helix-loop-helix DNA-binding domain
XP_003726300 PF07527 1.7e-13 Hairy_orange Hairy Orange

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003726300 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
XP_003726300 GO:0006351 biological_process transcription, DNA-templated
XP_003726300 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003726300 GO:0007219 biological_process Notch signaling pathway
XP_003726300 GO:0007275 biological_process multicellular organismal development
XP_003726300 GO:0045892 biological_process negative regulation of transcription, DNA-templated
XP_003726300 GO:0005634 cellular_component nucleus
XP_003726300 GO:0003677 molecular_function DNA binding
XP_003726300 GO:0043565 molecular_function sequence-specific DNA binding
XP_003726300 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9669 Mustela putorius furo 101691000 7897 Latimeria chalumnae 102355895
9606 Homo sapiens 3280 8364 Xenopus tropicalis 100038090
7425 Nasonia vitripennis 100117641 7029 Acyrthosiphon pisum 100163408
59729 Taeniopygia guttata 100225879 10224 Saccoglossus kowalevskii 100303558
28377 Anolis carolinensis 100558625 30195 Bombus terrestris 100643707
132113 Bombus impatiens 100742057 7463 Apis florea 100865915
143995 Megachile rotundata 100876689 34638 Metaseiulus occidentalis 100897626
9597 Pan paniscus 100975593 9555 Papio anubis 101006374
39432 Saimiri boliviensis 101047984 9595 Gorilla gorilla 101137927
43179 Ictidomys tridecemlineatus 101960521 13735 Pelodiscus sinensis 102463824
7227 Drosophila melanogaster 35800 9031 Gallus gallus 395128
9598 Pan troglodytes 460942 9913 Bos taurus 539547
7070 Tribolium castaneum 660626 7460 Apis mellifera 724914
9358 Choloepus hoffmanni ENSCHOG00000005633 7719 Ciona intestinalis ENSCING00000003929
51511 Ciona savignyi ENSCSAVG00000004162 9361 Dasypus novemcinctus ENSDNOG00000024495
10020 Dipodomys ordii ENSDORG00000014783 9796 Equus caballus ENSECAG00000026945
9685 Felis catus ENSFCAG00000029144 8049 Gadus morhua ENSGMOG00000018048
9315 Macropus eugenii ENSMEUG00000013941 9103 Meleagris gallopavo ENSMGAG00000007566
30608 Microcebus murinus ENSMICG00000012430 59463 Myotis lucifugus ENSMLUG00000008549
13616 Monodelphis domestica ENSMODG00000019833 61853 Nomascus leucogenys ENSNLEG00000006836
9258 Ornithorhynchus anatinus ENSOANG00000015683 8128 Oreochromis niloticus ENSONIG00000002619
9978 Ochotona princeps ENSOPRG00000006690 8090 Oryzias latipes ENSORLG00000007556
7757 Petromyzon marinus ENSPMAG00000001409 9601 Pongo abelii ENSPPYG00000014419
132908 Pteropus vampyrus ENSPVAG00000015487 10116 Rattus norvegicus ENSRNOG00000001720
9823 Sus scrofa ENSSSCG00000026362 99883 Tetraodon nigroviridis ENSTNIG00000015567
31033 Takifugu rubripes ENSTRUG00000001493 9739 Tursiops truncatus ENSTTRG00000001687
9646 Ailuropoda melanoleuca ENSAMEG00000015855 10141 Cavia porcellus ENSCPOG00000021042
69293 Gasterosteus aculeatus ENSGACG00000015969 8083 Xiphophorus maculatus ENSXMAG00000004442