Basic Information
Gene ID ENSRNOG00000001720 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Hes1
Full Name Transcription factor HES-1
Organism Rattus norvegicus [10116]

Cross Reference
UniProt D4ADT9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000002346 Gene3D G3DSA:4.10.280.10 IPR011598 33 94 1.40e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000002346 Pfam PF00010 IPR011598 35 92 2.10e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000002346 Pfam PF07527 IPR003650 113 154 3.30e-20 Orange
ENSRNOP00000002346 ProSiteProfiles PS50888 IPR011598 34 91 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000002346 ProSiteProfiles PS51054 IPR003650 114 147 0.00e-00 Orange
ENSRNOP00000002346 SMART SM00353 IPR011598 40 97 2.10e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000002346 SMART SM00511 IPR018352 112 156 6.70e-21 Orange subgroup
ENSRNOP00000002346 SUPERFAMILY SSF47459 IPR011598 25 94 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000002346 PF07527 1.9e-20 Hairy_orange Hairy Orange
ENSRNOP00000002346 PF00010 1.3e-14 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000002346 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSRNOP00000002346 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000002346 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSRNOP00000002346 GO:0007219 biological_process Notch signaling pathway
ENSRNOP00000002346 GO:0007275 biological_process multicellular organismal development
ENSRNOP00000002346 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSRNOP00000002346 GO:0005634 cellular_component nucleus
ENSRNOP00000002346 GO:0003677 molecular_function DNA binding
ENSRNOP00000002346 GO:0043565 molecular_function sequence-specific DNA binding
ENSRNOP00000002346 GO:0046982 molecular_function protein heterodimerization activity
ENSRNOP00000002346 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100117641 28377 Anolis carolinensis 100558625
30195 Bombus terrestris 100643707 132113 Bombus impatiens 100742057
7463 Apis florea 100865915 34638 Metaseiulus occidentalis 100897626
9597 Pan paniscus 100975593 9555 Papio anubis 101006374
9669 Mustela putorius furo 101691000 43179 Ictidomys tridecemlineatus 101960521
7897 Latimeria chalumnae 102355895 9606 Homo sapiens 3280
9031 Gallus gallus 395128 7668 Strongylocentrotus purpuratus 414294
9913 Bos taurus 539547 7070 Tribolium castaneum 660626
7460 Apis mellifera 724914 9646 Ailuropoda melanoleuca ENSAMEG00000015855
10141 Cavia porcellus ENSCPOG00000021042 9361 Dasypus novemcinctus ENSDNOG00000024495
10020 Dipodomys ordii ENSDORG00000014783 9796 Equus caballus ENSECAG00000026945
69293 Gasterosteus aculeatus ENSGACG00000009264 8049 Gadus morhua ENSGMOG00000015708
9315 Macropus eugenii ENSMEUG00000013941 13616 Monodelphis domestica ENSMODG00000019833
8128 Oreochromis niloticus ENSONIG00000002619 8090 Oryzias latipes ENSORLG00000007556
7757 Petromyzon marinus ENSPMAG00000001409 9601 Pongo abelii ENSPPYG00000014419
132908 Pteropus vampyrus ENSPVAG00000015487 7029 Acyrthosiphon pisum 100163408
59729 Taeniopygia guttata 100225879 10224 Saccoglossus kowalevskii 100303558
143995 Megachile rotundata 100876689 39432 Saimiri boliviensis 101047984
9595 Gorilla gorilla 101137927 13735 Pelodiscus sinensis 102463824
7227 Drosophila melanogaster 35800 9598 Pan troglodytes 460942
9358 Choloepus hoffmanni ENSCHOG00000005633 7719 Ciona intestinalis ENSCING00000003929
51511 Ciona savignyi ENSCSAVG00000004162 7955 Danio rerio ENSDARG00000019335
9371 Echinops telfairi ENSETEG00000019989 9685 Felis catus ENSFCAG00000029144
9103 Meleagris gallopavo ENSMGAG00000007566 30608 Microcebus murinus ENSMICG00000012430
59463 Myotis lucifugus ENSMLUG00000008549 61853 Nomascus leucogenys ENSNLEG00000006836
9258 Ornithorhynchus anatinus ENSOANG00000015683 9978 Ochotona princeps ENSOPRG00000006690
42254 Sorex araneus ENSSARG00000014246 9823 Sus scrofa ENSSSCG00000026362
99883 Tetraodon nigroviridis ENSTNIG00000015567 30538 Vicugna pacos ENSVPAG00000000708
8083 Xiphophorus maculatus ENSXMAG00000003794 37347 Tupaia belangeri ENSTBEG00000017537
31033 Takifugu rubripes ENSTRUG00000017395 9739 Tursiops truncatus ENSTTRG00000001687