Basic Information
Gene ID ENSPPYG00000014419
Gene Name HES1
Full Name Uncharacterized protein
Organism Pongo abelii [9601]

Cross Reference
UniProt H2PCE0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000016129 Gene3D G3DSA:4.10.280.10 IPR011598 33 94 7.00e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016129 Pfam PF00010 IPR011598 35 92 1.10e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016129 Pfam PF07527 IPR003650 109 150 1.80e-20 Orange
ENSPPYP00000016129 ProSiteProfiles PS50888 IPR011598 34 91 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016129 ProSiteProfiles PS51054 IPR003650 110 143 0.00e-00 Orange
ENSPPYP00000016129 SMART SM00353 IPR011598 40 97 2.10e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016129 SMART SM00511 IPR018352 108 152 6.70e-21 Orange subgroup
ENSPPYP00000016129 SUPERFAMILY SSF47459 IPR011598 25 94 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000016129 PF07527 1.1e-20 Hairy_orange Hairy Orange
ENSPPYP00000016129 PF00010 6.9e-15 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000016129 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSPPYP00000016129 GO:0006351 biological_process transcription, DNA-templated
ENSPPYP00000016129 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPPYP00000016129 GO:0007219 biological_process Notch signaling pathway
ENSPPYP00000016129 GO:0007275 biological_process multicellular organismal development
ENSPPYP00000016129 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSPPYP00000016129 GO:0005634 cellular_component nucleus
ENSPPYP00000016129 GO:0003677 molecular_function DNA binding
ENSPPYP00000016129 GO:0043565 molecular_function sequence-specific DNA binding
ENSPPYP00000016129 GO:0046982 molecular_function protein heterodimerization activity
ENSPPYP00000016129 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8364 Xenopus tropicalis 100038090 7425 Nasonia vitripennis 100117641
28377 Anolis carolinensis 100558625 30195 Bombus terrestris 100643707
132113 Bombus impatiens 100742057 7463 Apis florea 100865915
34638 Metaseiulus occidentalis 100897626 9597 Pan paniscus 100975593
9555 Papio anubis 101006374 9669 Mustela putorius furo 101691000
43179 Ictidomys tridecemlineatus 101960521 7897 Latimeria chalumnae 102355895
9606 Homo sapiens 3280 9031 Gallus gallus 395128
7668 Strongylocentrotus purpuratus 414294 7070 Tribolium castaneum 660626
7460 Apis mellifera 724914 9646 Ailuropoda melanoleuca ENSAMEG00000015855
9483 Callithrix jacchus ENSCJAG00000000166 10141 Cavia porcellus ENSCPOG00000021042
9361 Dasypus novemcinctus ENSDNOG00000024495 10020 Dipodomys ordii ENSDORG00000014783
9796 Equus caballus ENSECAG00000026945 69293 Gasterosteus aculeatus ENSGACG00000009264
8049 Gadus morhua ENSGMOG00000015708 9315 Macropus eugenii ENSMEUG00000013941
13616 Monodelphis domestica ENSMODG00000019833 30611 Otolemur garnettii ENSOGAG00000024214
8128 Oreochromis niloticus ENSONIG00000002619 8090 Oryzias latipes ENSORLG00000007556
7757 Petromyzon marinus ENSPMAG00000001409 7029 Acyrthosiphon pisum 100163408
59729 Taeniopygia guttata 100225879 10224 Saccoglossus kowalevskii 100303558
10029 Cricetulus griseus 100756407 143995 Megachile rotundata 100876689
39432 Saimiri boliviensis 101047984 9595 Gorilla gorilla 101137927
13735 Pelodiscus sinensis 102463824 7227 Drosophila melanogaster 35800
9598 Pan troglodytes 460942 9913 Bos taurus 539547
9615 Canis familiaris ENSCAFG00000019577 9358 Choloepus hoffmanni ENSCHOG00000005633
7719 Ciona intestinalis ENSCING00000003929 51511 Ciona savignyi ENSCSAVG00000004162
9365 Erinaceus europaeus ENSEEUG00000007286 9371 Echinops telfairi ENSETEG00000019989
9685 Felis catus ENSFCAG00000029144 9103 Meleagris gallopavo ENSMGAG00000007566
30608 Microcebus murinus ENSMICG00000012430 59463 Myotis lucifugus ENSMLUG00000008549
61853 Nomascus leucogenys ENSNLEG00000006836 9258 Ornithorhynchus anatinus ENSOANG00000015683
9978 Ochotona princeps ENSOPRG00000006690 9813 Procavia capensis ENSPCAG00000007135
10116 Rattus norvegicus ENSRNOG00000001720 42254 Sorex araneus ENSSARG00000014246
9823 Sus scrofa ENSSSCG00000026362 37347 Tupaia belangeri ENSTBEG00000017537
99883 Tetraodon nigroviridis ENSTNIG00000015567 30538 Vicugna pacos ENSVPAG00000000708
8083 Xiphophorus maculatus ENSXMAG00000003794 132908 Pteropus vampyrus ENSPVAG00000015487
9305 Sarcophilus harrisii ENSSHAG00000007537 31033 Takifugu rubripes ENSTRUG00000017395
9739 Tursiops truncatus ENSTTRG00000001687