Basic Information
Gene ID ENSEEUG00000001458
Gene Name ENSEEUG00000001458
Full Name ENSEEUG00000001458
Organism Erinaceus europaeus [9365]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSEEUP00000001314 Gene3D G3DSA:4.10.280.10 IPR011598 355 434 1.90e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSEEUP00000001314 Pfam PF00010 IPR011598 355 407 3.40e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSEEUP00000001314 Pfam PF01056 IPR012682 253 345 2.30e-36 Transcription regulator Myc, N-terminal
ENSEEUP00000001314 Pfam PF01056 IPR012682 5 163 3.00e-76 Transcription regulator Myc, N-terminal
ENSEEUP00000001314 Pfam PF02344 IPR003327 409 438 9.90e-16 Leucine zipper, Myc
ENSEEUP00000001314 PIRSF PIRSF001705 IPR002418 2 437 3.60e-196 Transcription regulator Myc
ENSEEUP00000001314 PRINTS PR00044 IPR002418 128 143 5.60e-51 Transcription regulator Myc
ENSEEUP00000001314 PRINTS PR00044 IPR002418 304 313 5.60e-51 Transcription regulator Myc
ENSEEUP00000001314 PRINTS PR00044 IPR002418 347 363 5.60e-51 Transcription regulator Myc
ENSEEUP00000001314 PRINTS PR00044 IPR002418 364 379 5.60e-51 Transcription regulator Myc
ENSEEUP00000001314 PRINTS PR00044 IPR002418 389 402 5.60e-51 Transcription regulator Myc
ENSEEUP00000001314 PRINTS PR00044 IPR002418 49 67 5.60e-51 Transcription regulator Myc
ENSEEUP00000001314 ProSiteProfiles PS50888 IPR011598 354 406 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSEEUP00000001314 SMART SM00353 IPR011598 360 412 7.60e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSEEUP00000001314 SUPERFAMILY SSF47459 IPR011598 352 435 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSEEUP00000001314 PF01056 0 Myc_N Myc amino-terminal region
ENSEEUP00000001314 PF00010 3.1e-16 HLH Helix-loop-helix DNA-binding domain
ENSEEUP00000001314 PF02344 9.9e-16 Myc-LZ Myc leucine zipper domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSEEUP00000001314 GO:0000165 biological_process MAPK cascade
ENSEEUP00000001314 GO:0006338 biological_process chromatin remodeling
ENSEEUP00000001314 GO:0006351 biological_process transcription, DNA-templated
ENSEEUP00000001314 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSEEUP00000001314 GO:0006879 biological_process cellular iron ion homeostasis
ENSEEUP00000001314 GO:0006974 biological_process cellular response to DNA damage stimulus
ENSEEUP00000001314 GO:0010332 biological_process response to gamma radiation
ENSEEUP00000001314 GO:0032204 biological_process regulation of telomere maintenance
ENSEEUP00000001314 GO:0032873 biological_process negative regulation of stress-activated MAPK cascade
ENSEEUP00000001314 GO:0042493 biological_process response to drug
ENSEEUP00000001314 GO:0043066 biological_process negative regulation of apoptotic process
ENSEEUP00000001314 GO:0043280 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
ENSEEUP00000001314 GO:0045656 biological_process negative regulation of monocyte differentiation
ENSEEUP00000001314 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSEEUP00000001314 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSEEUP00000001314 GO:0048146 biological_process positive regulation of fibroblast proliferation
ENSEEUP00000001314 GO:0050679 biological_process positive regulation of epithelial cell proliferation
ENSEEUP00000001314 GO:0051276 biological_process chromosome organization
ENSEEUP00000001314 GO:0051782 biological_process negative regulation of cell division
ENSEEUP00000001314 GO:0060070 biological_process canonical Wnt signaling pathway
ENSEEUP00000001314 GO:2000573 biological_process positive regulation of DNA biosynthetic process
ENSEEUP00000001314 GO:2001022 biological_process positive regulation of response to DNA damage stimulus
ENSEEUP00000001314 GO:0005634 cellular_component nucleus
ENSEEUP00000001314 GO:0005654 cellular_component nucleoplasm
ENSEEUP00000001314 GO:0005730 cellular_component nucleolus
ENSEEUP00000001314 GO:0003677 molecular_function DNA binding
ENSEEUP00000001314 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSEEUP00000001314 GO:0032403 molecular_function protein complex binding
ENSEEUP00000001314 GO:0046983 molecular_function protein dimerization activity
ENSEEUP00000001314 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100303478 10029 Cricetulus griseus 100758352
9597 Pan paniscus 100972175 9555 Papio anubis 101000645
39432 Saimiri boliviensis 101047066 43179 Ictidomys tridecemlineatus 101957086
8083 Xiphophorus maculatus 102224917 7897 Latimeria chalumnae 102357079
10090 Mus musculus 18109 7955 Danio rerio 393141
9031 Gallus gallus 420332 9606 Homo sapiens 4609
9544 Macaca mulatta 694626 28377 Anolis carolinensis ENSACAG00000010372
9646 Ailuropoda melanoleuca ENSAMEG00000014717 9913 Bos taurus ENSBTAG00000023372
9615 Canis familiaris ENSCAFG00000001086 9483 Callithrix jacchus ENSCJAG00000012620
10141 Cavia porcellus ENSCPOG00000003326 10020 Dipodomys ordii ENSDORG00000010277
9796 Equus caballus ENSECAG00000002896 9371 Echinops telfairi ENSETEG00000007657
9685 Felis catus ENSFCAG00000025438 69293 Gasterosteus aculeatus ENSGACG00000004456
9595 Gorilla gorilla ENSGGOG00000012135 8049 Gadus morhua ENSGMOG00000006081
9785 Loxodonta africana ENSLAFG00000001410 9315 Macropus eugenii ENSMEUG00000006124
9103 Meleagris gallopavo ENSMGAG00000015875 30608 Microcebus murinus ENSMICG00000014990
59463 Myotis lucifugus ENSMLUG00000026933 13616 Monodelphis domestica ENSMODG00000001735
9669 Mustela putorius furo ENSMPUG00000001327 9258 Ornithorhynchus anatinus ENSOANG00000008107
9986 Oryctolagus cuniculus ENSOCUG00000014289 30611 Otolemur garnettii ENSOGAG00000005372
8128 Oreochromis niloticus ENSONIG00000013987 9978 Ochotona princeps ENSOPRG00000011259
8090 Oryzias latipes ENSORLG00000007021 9813 Procavia capensis ENSPCAG00000008554
7757 Petromyzon marinus ENSPMAG00000010212 9601 Pongo abelii ENSPPYG00000018878
13735 Pelodiscus sinensis ENSPSIG00000008301 9598 Pan troglodytes ENSPTRG00000020581
10116 Rattus norvegicus ENSRNOG00000004500 42254 Sorex araneus ENSSARG00000010372
9823 Sus scrofa ENSSSCG00000005965 37347 Tupaia belangeri ENSTBEG00000005715
59729 Taeniopygia guttata ENSTGUG00000012513 99883 Tetraodon nigroviridis ENSTNIG00000017136
31033 Takifugu rubripes ENSTRUG00000008797 9739 Tursiops truncatus ENSTTRG00000016278
30538 Vicugna pacos ENSVPAG00000005895 132908 Pteropus vampyrus ENSPVAG00000010355