Basic Information
Gene ID ENSSSCG00000005965
Gene Name MYC; c-Myc
Full Name Myc proto-oncogene protein
Organism Sus scrofa [9823]

Cross Reference
UniProt F1RRR8 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSSCP00000006374 Gene3D G3DSA:4.10.280.10 IPR011598 355 427 4.90e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSSCP00000006374 Pfam PF00010 IPR011598 355 407 3.90e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSSCP00000006374 Pfam PF01056 IPR012682 1 345 2.20e-143 Transcription regulator Myc, N-terminal
ENSSSCP00000006374 Pfam PF02344 IPR003327 408 438 2.30e-17 Leucine zipper, Myc
ENSSSCP00000006374 PIRSF PIRSF001705 IPR002418 1 437 0.00e-00 Transcription regulator Myc
ENSSSCP00000006374 PRINTS PR00044 IPR002418 128 143 5.30e-51 Transcription regulator Myc
ENSSSCP00000006374 PRINTS PR00044 IPR002418 304 313 5.30e-51 Transcription regulator Myc
ENSSSCP00000006374 PRINTS PR00044 IPR002418 347 363 5.30e-51 Transcription regulator Myc
ENSSSCP00000006374 PRINTS PR00044 IPR002418 364 379 5.30e-51 Transcription regulator Myc
ENSSSCP00000006374 PRINTS PR00044 IPR002418 389 402 5.30e-51 Transcription regulator Myc
ENSSSCP00000006374 PRINTS PR00044 IPR002418 45 63 5.30e-51 Transcription regulator Myc
ENSSSCP00000006374 ProSiteProfiles PS50888 IPR011598 354 406 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSSCP00000006374 SMART SM00353 IPR011598 360 412 3.60e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSSCP00000006374 SUPERFAMILY SSF47459 IPR011598 352 434 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSSCP00000006374 PF01056 0 Myc_N Myc amino-terminal region
ENSSSCP00000006374 PF02344 2.3e-17 Myc-LZ Myc leucine zipper domain
ENSSSCP00000006374 PF00010 2.9e-17 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSSCP00000006374 GO:0000165 biological_process MAPK cascade
ENSSSCP00000006374 GO:0006338 biological_process chromatin remodeling
ENSSSCP00000006374 GO:0006351 biological_process transcription, DNA-templated
ENSSSCP00000006374 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSSSCP00000006374 GO:0006879 biological_process cellular iron ion homeostasis
ENSSSCP00000006374 GO:0006974 biological_process cellular response to DNA damage stimulus
ENSSSCP00000006374 GO:0008284 biological_process positive regulation of cell proliferation
ENSSSCP00000006374 GO:0010332 biological_process response to gamma radiation
ENSSSCP00000006374 GO:0032204 biological_process regulation of telomere maintenance
ENSSSCP00000006374 GO:0032873 biological_process negative regulation of stress-activated MAPK cascade
ENSSSCP00000006374 GO:0042493 biological_process response to drug
ENSSSCP00000006374 GO:0043066 biological_process negative regulation of apoptotic process
ENSSSCP00000006374 GO:0043280 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
ENSSSCP00000006374 GO:0045656 biological_process negative regulation of monocyte differentiation
ENSSSCP00000006374 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSSSCP00000006374 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSSSCP00000006374 GO:0048146 biological_process positive regulation of fibroblast proliferation
ENSSSCP00000006374 GO:0050679 biological_process positive regulation of epithelial cell proliferation
ENSSSCP00000006374 GO:0051276 biological_process chromosome organization
ENSSSCP00000006374 GO:0051782 biological_process negative regulation of cell division
ENSSSCP00000006374 GO:0060070 biological_process canonical Wnt signaling pathway
ENSSSCP00000006374 GO:2000573 biological_process positive regulation of DNA biosynthetic process
ENSSSCP00000006374 GO:2001022 biological_process positive regulation of response to DNA damage stimulus
ENSSSCP00000006374 GO:0005634 cellular_component nucleus
ENSSSCP00000006374 GO:0005654 cellular_component nucleoplasm
ENSSSCP00000006374 GO:0005730 cellular_component nucleolus
ENSSSCP00000006374 GO:0003677 molecular_function DNA binding
ENSSSCP00000006374 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSSCP00000006374 GO:0032403 molecular_function protein complex binding
ENSSSCP00000006374 GO:0046983 molecular_function protein dimerization activity
ENSSSCP00000006374 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100303478 10029 Cricetulus griseus 100758352
9597 Pan paniscus 100972175 9555 Papio anubis 101000645
43179 Ictidomys tridecemlineatus 101957086 8083 Xiphophorus maculatus 102224917
7897 Latimeria chalumnae 102357079 7668 Strongylocentrotus purpuratus 373385
7955 Danio rerio 393141 9031 Gallus gallus 420332
28377 Anolis carolinensis ENSACAG00000010372 9646 Ailuropoda melanoleuca ENSAMEG00000014717
9913 Bos taurus ENSBTAG00000023372 9483 Callithrix jacchus ENSCJAG00000012620
10141 Cavia porcellus ENSCPOG00000003326 10020 Dipodomys ordii ENSDORG00000010277
9796 Equus caballus ENSECAG00000002896 9365 Erinaceus europaeus ENSEEUG00000001458
9371 Echinops telfairi ENSETEG00000007657 9685 Felis catus ENSFCAG00000025438
69293 Gasterosteus aculeatus ENSGACG00000004456 9595 Gorilla gorilla ENSGGOG00000012135
8049 Gadus morhua ENSGMOG00000006081 9785 Loxodonta africana ENSLAFG00000001410
9315 Macropus eugenii ENSMEUG00000006124 9103 Meleagris gallopavo ENSMGAG00000015875
30608 Microcebus murinus ENSMICG00000014990 59463 Myotis lucifugus ENSMLUG00000026933
13616 Monodelphis domestica ENSMODG00000001735 9669 Mustela putorius furo ENSMPUG00000001327
9986 Oryctolagus cuniculus ENSOCUG00000014289 30611 Otolemur garnettii ENSOGAG00000005372
9978 Ochotona princeps ENSOPRG00000011259 8090 Oryzias latipes ENSORLG00000007021
9813 Procavia capensis ENSPCAG00000008554 7757 Petromyzon marinus ENSPMAG00000003103
9601 Pongo abelii ENSPPYG00000018878 13735 Pelodiscus sinensis ENSPSIG00000008301
9598 Pan troglodytes ENSPTRG00000020581 132908 Pteropus vampyrus ENSPVAG00000010355
10116 Rattus norvegicus ENSRNOG00000004500 42254 Sorex araneus ENSSARG00000010372
39432 Saimiri boliviensis 101047066 10090 Mus musculus 18109
9606 Homo sapiens 4609 9544 Macaca mulatta 694626
9615 Canis familiaris ENSCAFG00000001086 9258 Ornithorhynchus anatinus ENSOANG00000008107
8128 Oreochromis niloticus ENSONIG00000013987 30538 Vicugna pacos ENSVPAG00000005895
8364 Xenopus tropicalis ENSXETG00000015485 37347 Tupaia belangeri ENSTBEG00000005715
59729 Taeniopygia guttata ENSTGUG00000012513 99883 Tetraodon nigroviridis ENSTNIG00000017136
31033 Takifugu rubripes ENSTRUG00000008797 9739 Tursiops truncatus ENSTTRG00000016278