Basic Information
Gene ID ENSSARG00000010372
Gene Name ENSSARG00000010372
Full Name ENSSARG00000010372
Organism Sorex araneus [42254]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSARP00000009372 Gene3D G3DSA:4.10.280.10 IPR011598 356 429 3.80e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSARP00000009372 Pfam PF00010 IPR011598 356 408 2.20e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSARP00000009372 Pfam PF01056 IPR012682 5 346 1.60e-138 Transcription regulator Myc, N-terminal
ENSSARP00000009372 Pfam PF02344 IPR003327 410 440 2.60e-18 Leucine zipper, Myc
ENSSARP00000009372 PIRSF PIRSF001705 IPR002418 2 438 1.20e-299 Transcription regulator Myc
ENSSARP00000009372 PRINTS PR00044 IPR002418 132 147 8.10e-51 Transcription regulator Myc
ENSSARP00000009372 PRINTS PR00044 IPR002418 305 314 8.10e-51 Transcription regulator Myc
ENSSARP00000009372 PRINTS PR00044 IPR002418 348 364 8.10e-51 Transcription regulator Myc
ENSSARP00000009372 PRINTS PR00044 IPR002418 365 380 8.10e-51 Transcription regulator Myc
ENSSARP00000009372 PRINTS PR00044 IPR002418 390 403 8.10e-51 Transcription regulator Myc
ENSSARP00000009372 PRINTS PR00044 IPR002418 49 67 8.10e-51 Transcription regulator Myc
ENSSARP00000009372 ProSiteProfiles PS50888 IPR011598 355 407 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSARP00000009372 SMART SM00353 IPR011598 361 413 3.70e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSSARP00000009372 SUPERFAMILY SSF47459 IPR011598 353 436 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSARP00000009372 PF01056 0 Myc_N Myc amino-terminal region
ENSSARP00000009372 PF02344 2.6e-18 Myc-LZ Myc leucine zipper domain
ENSSARP00000009372 PF00010 6.2e-17 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSARP00000009372 GO:0000165 biological_process MAPK cascade
ENSSARP00000009372 GO:0006338 biological_process chromatin remodeling
ENSSARP00000009372 GO:0006351 biological_process transcription, DNA-templated
ENSSARP00000009372 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSSARP00000009372 GO:0006879 biological_process cellular iron ion homeostasis
ENSSARP00000009372 GO:0006974 biological_process cellular response to DNA damage stimulus
ENSSARP00000009372 GO:0010332 biological_process response to gamma radiation
ENSSARP00000009372 GO:0032204 biological_process regulation of telomere maintenance
ENSSARP00000009372 GO:0032873 biological_process negative regulation of stress-activated MAPK cascade
ENSSARP00000009372 GO:0042493 biological_process response to drug
ENSSARP00000009372 GO:0043066 biological_process negative regulation of apoptotic process
ENSSARP00000009372 GO:0043280 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
ENSSARP00000009372 GO:0045656 biological_process negative regulation of monocyte differentiation
ENSSARP00000009372 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSSARP00000009372 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSSARP00000009372 GO:0048146 biological_process positive regulation of fibroblast proliferation
ENSSARP00000009372 GO:0050679 biological_process positive regulation of epithelial cell proliferation
ENSSARP00000009372 GO:0051276 biological_process chromosome organization
ENSSARP00000009372 GO:0051782 biological_process negative regulation of cell division
ENSSARP00000009372 GO:0060070 biological_process canonical Wnt signaling pathway
ENSSARP00000009372 GO:2000573 biological_process positive regulation of DNA biosynthetic process
ENSSARP00000009372 GO:2001022 biological_process positive regulation of response to DNA damage stimulus
ENSSARP00000009372 GO:0005634 cellular_component nucleus
ENSSARP00000009372 GO:0005654 cellular_component nucleoplasm
ENSSARP00000009372 GO:0005730 cellular_component nucleolus
ENSSARP00000009372 GO:0003677 molecular_function DNA binding
ENSSARP00000009372 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSARP00000009372 GO:0032403 molecular_function protein complex binding
ENSSARP00000009372 GO:0046983 molecular_function protein dimerization activity
ENSSARP00000009372 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys 100607514 10029 Cricetulus griseus 100758352
8083 Xiphophorus maculatus 102224917 7897 Latimeria chalumnae 102357079
7955 Danio rerio 393141 28377 Anolis carolinensis ENSACAG00000010372
9483 Callithrix jacchus ENSCJAG00000012620 10141 Cavia porcellus ENSCPOG00000003326
10020 Dipodomys ordii ENSDORG00000010277 9796 Equus caballus ENSECAG00000002896
9365 Erinaceus europaeus ENSEEUG00000001458 9685 Felis catus ENSFCAG00000025438
69293 Gasterosteus aculeatus ENSGACG00000004456 9785 Loxodonta africana ENSLAFG00000001410
9103 Meleagris gallopavo ENSMGAG00000015875 30608 Microcebus murinus ENSMICG00000014990
9669 Mustela putorius furo ENSMPUG00000001327 30611 Otolemur garnettii ENSOGAG00000005372
8090 Oryzias latipes ENSORLG00000007021 9813 Procavia capensis ENSPCAG00000008554
9598 Pan troglodytes ENSPTRG00000020581 132908 Pteropus vampyrus ENSPVAG00000010355
10224 Saccoglossus kowalevskii 100303478 9597 Pan paniscus 100972175
9555 Papio anubis 101000645 39432 Saimiri boliviensis 101047066
43179 Ictidomys tridecemlineatus 101957086 10090 Mus musculus 18109
9031 Gallus gallus 420332 9606 Homo sapiens 4609
9544 Macaca mulatta 694626 9646 Ailuropoda melanoleuca ENSAMEG00000014717
9913 Bos taurus ENSBTAG00000023372 9615 Canis familiaris ENSCAFG00000001086
9371 Echinops telfairi ENSETEG00000007657 9595 Gorilla gorilla ENSGGOG00000012135
8049 Gadus morhua ENSGMOG00000006081 9315 Macropus eugenii ENSMEUG00000006124
59463 Myotis lucifugus ENSMLUG00000026933 13616 Monodelphis domestica ENSMODG00000001735
9258 Ornithorhynchus anatinus ENSOANG00000008107 9986 Oryctolagus cuniculus ENSOCUG00000014289
8128 Oreochromis niloticus ENSONIG00000013987 9978 Ochotona princeps ENSOPRG00000011259
7757 Petromyzon marinus ENSPMAG00000003103 9601 Pongo abelii ENSPPYG00000018878
13735 Pelodiscus sinensis ENSPSIG00000008301 10116 Rattus norvegicus ENSRNOG00000004500
9823 Sus scrofa ENSSSCG00000005965 59729 Taeniopygia guttata ENSTGUG00000012513
31033 Takifugu rubripes ENSTRUG00000008797 9478 Tarsius syrichta ENSTSYG00000009275
9739 Tursiops truncatus ENSTTRG00000016278 30538 Vicugna pacos ENSVPAG00000005895
8364 Xenopus tropicalis ENSXETG00000015485 37347 Tupaia belangeri ENSTBEG00000005715
99883 Tetraodon nigroviridis ENSTNIG00000017136