Basic Information
Gene ID ENSOGAG00000002010
Gene Name THRB
Full Name Uncharacterized protein
Organism Otolemur garnettii [30611]

Cross Reference
UniProt H0WJU5 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOGAP00000001792 Gene3D G3DSA:1.10.565.10 IPR008946 182 459 6.70e-75 Nuclear hormone receptor, ligand-binding
ENSOGAP00000001792 Gene3D G3DSA:3.30.50.10 IPR013088 104 181 2.40e-29 Zinc finger, NHR/GATA-type
ENSOGAP00000001792 Pfam PF00104 IPR000536 267 430 1.10e-21 Nuclear hormone receptor, ligand-binding, core
ENSOGAP00000001792 Pfam PF00105 IPR001628 105 174 3.00e-30 Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 PRINTS PR00047 IPR001628 106 122 1.20e-18 Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 PRINTS PR00047 IPR001628 122 137 1.20e-18 Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 PRINTS PR00047 IPR001628 157 165 1.20e-18 Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 PRINTS PR00047 IPR001628 165 173 1.20e-18 Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 PRINTS PR00398 IPR001723 169 179 9.20e-30 Steroid hormone receptor
ENSOGAP00000001792 PRINTS PR00398 IPR001723 274 295 9.20e-30 Steroid hormone receptor
ENSOGAP00000001792 PRINTS PR00398 IPR001723 295 311 9.20e-30 Steroid hormone receptor
ENSOGAP00000001792 PRINTS PR00398 IPR001723 362 377 9.20e-30 Steroid hormone receptor
ENSOGAP00000001792 PRINTS PR00398 IPR001723 419 436 9.20e-30 Steroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 132 143 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 171 187 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 188 206 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 211 228 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 234 253 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 271 292 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 297 316 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 362 384 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 PRINTS PR00546 IPR001728 94 108 4.00e-101 Thyroid hormone receptor
ENSOGAP00000001792 ProSitePatterns PS00031 IPR001628 106 132 - Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 ProSiteProfiles PS51030 IPR001628 103 180 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 SMART SM00399 IPR001628 103 176 1.30e-39 Zinc finger, nuclear hormone receptor-type
ENSOGAP00000001792 SMART SM00430 IPR000536 273 431 2.40e-33 Nuclear hormone receptor, ligand-binding, core
ENSOGAP00000001792 SUPERFAMILY SSF48508 IPR008946 214 458 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOGAP00000001792 PF00105 1.5e-30 zf-C4 Zinc finger, C4 type (two domains)
ENSOGAP00000001792 PF00104 2.7e-22 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOGAP00000001792 GO:0006351 biological_process transcription, DNA-templated
ENSOGAP00000001792 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSOGAP00000001792 GO:0030522 biological_process intracellular receptor signaling pathway
ENSOGAP00000001792 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSOGAP00000001792 GO:0005634 cellular_component nucleus
ENSOGAP00000001792 GO:0003677 molecular_function DNA binding
ENSOGAP00000001792 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOGAP00000001792 GO:0003707 molecular_function steroid hormone receptor activity
ENSOGAP00000001792 GO:0004887 molecular_function thyroid hormone receptor activity
ENSOGAP00000001792 GO:0008270 molecular_function zinc ion binding
ENSOGAP00000001792 GO:0043565 molecular_function sequence-specific DNA binding
ENSOGAP00000001792 GO:0046872 molecular_function metal ion binding
ENSOGAP00000001792 GO:0070324 molecular_function thyroid hormone binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100313752 8128 Oreochromis niloticus 100702392
39432 Saimiri boliviensis 101050682 9669 Mustela putorius furo 101673177
43179 Ictidomys tridecemlineatus 101973293 8083 Xiphophorus maculatus 102237580
7897 Latimeria chalumnae 102345437 13735 Pelodiscus sinensis 102448851
9606 Homo sapiens 7068 9646 Ailuropoda melanoleuca ENSAMEG00000017962
9615 Canis familiaris ENSCAFG00000016173 7719 Ciona intestinalis ENSCING00000021968
10141 Cavia porcellus ENSCPOG00000010519 51511 Ciona savignyi ENSCSAVG00000006056
10020 Dipodomys ordii ENSDORG00000004966 69293 Gasterosteus aculeatus ENSGACG00000007996
9031 Gallus gallus ENSGALG00000000270 9595 Gorilla gorilla ENSGGOG00000007268
8049 Gadus morhua ENSGMOG00000008051 30608 Microcebus murinus ENSMICG00000011433
59463 Myotis lucifugus ENSMLUG00000009632 13616 Monodelphis domestica ENSMODG00000014903
61853 Nomascus leucogenys ENSNLEG00000001519 9258 Ornithorhynchus anatinus ENSOANG00000012237
9796 Equus caballus 100051615 9483 Callithrix jacchus 100394325
9103 Meleagris gallopavo 100545018 10029 Cricetulus griseus 100770653
9597 Pan paniscus 100993061 9555 Papio anubis 101007506
10090 Mus musculus 21834 7668 Strongylocentrotus purpuratus 584535
9544 Macaca mulatta 699969 28377 Anolis carolinensis ENSACAG00000002898
9913 Bos taurus ENSBTAG00000017802 9358 Choloepus hoffmanni ENSCHOG00000000987
9361 Dasypus novemcinctus ENSDNOG00000017243 9365 Erinaceus europaeus ENSEEUG00000005916
9371 Echinops telfairi ENSETEG00000016652 9685 Felis catus ENSFCAG00000022754
9785 Loxodonta africana ENSLAFG00000013921 9315 Macropus eugenii ENSMEUG00000010735
8090 Oryzias latipes ENSORLG00000012005 9601 Pongo abelii ENSPPYG00000014063
9598 Pan troglodytes ENSPTRG00000009112 132908 Pteropus vampyrus ENSPVAG00000001768
10116 Rattus norvegicus ENSRNOG00000006649 59729 Taeniopygia guttata ENSTGUG00000003349
30538 Vicugna pacos ENSVPAG00000005832 9978 Ochotona princeps ENSOPRG00000012107
9813 Procavia capensis ENSPCAG00000012625 7757 Petromyzon marinus ENSPMAG00000005715
42254 Sorex araneus ENSSARG00000013590 9305 Sarcophilus harrisii ENSSHAG00000004159
9823 Sus scrofa ENSSSCG00000011211 37347 Tupaia belangeri ENSTBEG00000004123
99883 Tetraodon nigroviridis ENSTNIG00000009795 31033 Takifugu rubripes ENSTRUG00000008015
9478 Tarsius syrichta ENSTSYG00000008478 9739 Tursiops truncatus ENSTTRG00000001859
8364 Xenopus tropicalis ENSXETG00000003871