Basic Information | |||
Gene ID | ENSRNOG00000006649 ; ![]() ![]() | ||
Gene Name | Thrb; TRbeta2Delta | ||
Full Name | Thyroid hormone receptor beta | ||
Organism | Rattus norvegicus [10116] |
Cross Reference | |||
UniProt | D3ZGG0 | UniGene | Rn.34019 |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSRNOP00000008752 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 233 | 510 | 2.30e-74 | Nuclear hormone receptor, ligand-binding |
ENSRNOP00000008752 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 119 | 142 | 8.90e-28 | Zinc finger, NHR/GATA-type |
ENSRNOP00000008752 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 179 | 232 | 8.90e-28 | Zinc finger, NHR/GATA-type |
ENSRNOP00000008752 | Pfam | PF00104 | IPR000536 | 318 | 481 | 7.90e-22 | Nuclear hormone receptor, ligand-binding, core |
ENSRNOP00000008752 | Pfam | PF00105 | IPR001628 | 120 | 148 | 6.40e-09 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | Pfam | PF00105 | IPR001628 | 178 | 225 | 9.90e-17 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | PRINTS | PR00047 | IPR001628 | 121 | 137 | 3.30e-12 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | PRINTS | PR00047 | IPR001628 | 137 | 152 | 3.30e-12 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | PRINTS | PR00047 | IPR001628 | 208 | 216 | 3.30e-12 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | PRINTS | PR00047 | IPR001628 | 216 | 224 | 3.30e-12 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | PRINTS | PR00398 | IPR001723 | 220 | 230 | 1.50e-29 | Steroid hormone receptor |
ENSRNOP00000008752 | PRINTS | PR00398 | IPR001723 | 325 | 346 | 1.50e-29 | Steroid hormone receptor |
ENSRNOP00000008752 | PRINTS | PR00398 | IPR001723 | 346 | 362 | 1.50e-29 | Steroid hormone receptor |
ENSRNOP00000008752 | PRINTS | PR00398 | IPR001723 | 413 | 428 | 1.50e-29 | Steroid hormone receptor |
ENSRNOP00000008752 | PRINTS | PR00398 | IPR001723 | 470 | 487 | 1.50e-29 | Steroid hormone receptor |
ENSRNOP00000008752 | PRINTS | PR00546 | IPR001728 | 109 | 123 | 5.40e-06 | Thyroid hormone receptor |
ENSRNOP00000008752 | PRINTS | PR00546 | IPR001728 | 243 | 262 | 5.40e-06 | Thyroid hormone receptor |
ENSRNOP00000008752 | ProSiteProfiles | PS51030 | IPR001628 | 118 | 231 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | SMART | SM00399 | IPR001628 | 118 | 227 | 5.40e-33 | Zinc finger, nuclear hormone receptor-type |
ENSRNOP00000008752 | SMART | SM00430 | IPR000536 | 324 | 482 | 3.00e-33 | Nuclear hormone receptor, ligand-binding, core |
ENSRNOP00000008752 | SUPERFAMILY | SSF48508 | IPR008946 | 265 | 509 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSRNOP00000008752 | PF00105 | 2.2e-26 | zf-C4 | Zinc finger, C4 type (two domains) |
ENSRNOP00000008752 | PF00104 | 4.3e-22 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSRNOP00000008752 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSRNOP00000008752 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSRNOP00000008752 | GO:0030522 | biological_process | intracellular receptor signaling pathway |
ENSRNOP00000008752 | GO:0043401 | biological_process | steroid hormone mediated signaling pathway |
ENSRNOP00000008752 | GO:0005634 | cellular_component | nucleus |
ENSRNOP00000008752 | GO:0003677 | molecular_function | DNA binding |
ENSRNOP00000008752 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSRNOP00000008752 | GO:0003707 | molecular_function | steroid hormone receptor activity |
ENSRNOP00000008752 | GO:0004887 | molecular_function | thyroid hormone receptor activity |
ENSRNOP00000008752 | GO:0008270 | molecular_function | zinc ion binding |
ENSRNOP00000008752 | GO:0043565 | molecular_function | sequence-specific DNA binding |
ENSRNOP00000008752 | GO:0046872 | molecular_function | metal ion binding |
ENSRNOP00000008752 | GO:0070324 | molecular_function | thyroid hormone binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9796 | Equus caballus | 100051615 | 10224 | Saccoglossus kowalevskii | 100313752 |
9483 | Callithrix jacchus | 100394325 | 9103 | Meleagris gallopavo | 100545018 |
8128 | Oreochromis niloticus | 100702392 | 9597 | Pan paniscus | 100993061 |
39432 | Saimiri boliviensis | 101050682 | 9669 | Mustela putorius furo | 101673177 |
43179 | Ictidomys tridecemlineatus | 101973293 | 13735 | Pelodiscus sinensis | 102448851 |
7668 | Strongylocentrotus purpuratus | 584535 | 9544 | Macaca mulatta | 699969 |
9606 | Homo sapiens | 7068 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000017962 |
9913 | Bos taurus | ENSBTAG00000017802 | 9358 | Choloepus hoffmanni | ENSCHOG00000000987 |
10141 | Cavia porcellus | ENSCPOG00000010519 | 51511 | Ciona savignyi | ENSCSAVG00000006056 |
10020 | Dipodomys ordii | ENSDORG00000004966 | 9365 | Erinaceus europaeus | ENSEEUG00000005916 |
9371 | Echinops telfairi | ENSETEG00000016652 | 9685 | Felis catus | ENSFCAG00000022754 |
69293 | Gasterosteus aculeatus | ENSGACG00000007996 | 9595 | Gorilla gorilla | ENSGGOG00000007268 |
8049 | Gadus morhua | ENSGMOG00000008051 | 9785 | Loxodonta africana | ENSLAFG00000013921 |
9315 | Macropus eugenii | ENSMEUG00000010735 | 30608 | Microcebus murinus | ENSMICG00000011433 |
59463 | Myotis lucifugus | ENSMLUG00000009632 | 13616 | Monodelphis domestica | ENSMODG00000014903 |
9258 | Ornithorhynchus anatinus | ENSOANG00000012237 | 30611 | Otolemur garnettii | ENSOGAG00000002010 |
9813 | Procavia capensis | ENSPCAG00000012625 | 7757 | Petromyzon marinus | ENSPMAG00000005715 |
9601 | Pongo abelii | ENSPPYG00000014063 | 132908 | Pteropus vampyrus | ENSPVAG00000001768 |
9555 | Papio anubis | 101007506 | 10090 | Mus musculus | 21834 |
42254 | Sorex araneus | ENSSARG00000013590 | 9305 | Sarcophilus harrisii | ENSSHAG00000004159 |
9823 | Sus scrofa | ENSSSCG00000011211 | 37347 | Tupaia belangeri | ENSTBEG00000004123 |
59729 | Taeniopygia guttata | ENSTGUG00000003349 | 99883 | Tetraodon nigroviridis | ENSTNIG00000009795 |
31033 | Takifugu rubripes | ENSTRUG00000008015 | 9478 | Tarsius syrichta | ENSTSYG00000008478 |
9739 | Tursiops truncatus | ENSTTRG00000001859 | 30538 | Vicugna pacos | ENSVPAG00000005832 |
8364 | Xenopus tropicalis | ENSXETG00000003871 |
Paralogs | |||
81812 |