Basic Information
Gene ID ENSPCAG00000011584
Gene Name ENSPCAG00000011584
Full Name ENSPCAG00000011584
Organism Procavia capensis [9813]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPCAP00000010872 Pfam PF08447 IPR013655 284 334 2.40e-08 PAS fold-3
ENSPCAP00000010872 Pfam PF08778 IPR014887 779 818 1.50e-22 HIF-1 alpha, transactivation domain, C-terminal
ENSPCAP00000010872 Pfam PF11413 IPR021537 545 577 4.70e-16 Hypoxia-inducible factor, alpha subunit
ENSPCAP00000010872 ProSiteProfiles PS50112 IPR000014 94 148 0.00e-00 PAS domain
ENSPCAP00000010872 ProSiteProfiles PS50888 IPR011598 18 71 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPCAP00000010872 SMART SM00086 IPR001610 297 340 2.60e-11 PAC motif
ENSPCAP00000010872 SMART SM00091 IPR000014 88 153 2.00e-09 PAS domain
ENSPCAP00000010872 SMART SM00353 IPR011598 24 79 1.80e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPCAP00000010872 SUPERFAMILY SSF47459 IPR011598 16 71 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPCAP00000010872 SUPERFAMILY SSF55785 IPR000014 286 338 0.00e-00 PAS domain
ENSPCAP00000010872 SUPERFAMILY SSF55785 IPR000014 95 147 0.00e-00 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPCAP00000010872 PF08778 8.9e-23 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSPCAP00000010872 PF11413 2.5e-16 HIF-1 Hypoxia-inducible factor-1
ENSPCAP00000010872 PF08447 1.6e-13 PAS_3 PAS fold
ENSPCAP00000010872 PF14598 3e-11 PAS_11 PAS domain
ENSPCAP00000010872 PF00989 5e-05 PAS PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPCAP00000010872 GO:0001666 biological_process response to hypoxia
ENSPCAP00000010872 GO:0006351 biological_process transcription, DNA-templated
ENSPCAP00000010872 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPCAP00000010872 GO:0007165 biological_process signal transduction
ENSPCAP00000010872 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPCAP00000010872 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSPCAP00000010872 GO:0071456 biological_process cellular response to hypoxia
ENSPCAP00000010872 GO:0005634 cellular_component nucleus
ENSPCAP00000010872 GO:0005737 cellular_component cytoplasm
ENSPCAP00000010872 GO:0003677 molecular_function DNA binding
ENSPCAP00000010872 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPCAP00000010872 GO:0004871 molecular_function signal transducer activity
ENSPCAP00000010872 GO:0035035 molecular_function histone acetyltransferase binding
ENSPCAP00000010872 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
30608 Microcebus murinus ENSMICG00000002224 9258 Ornithorhynchus anatinus ENSOANG00000009092
9483 Callithrix jacchus 100411678 9597 Pan paniscus 100993223
9555 Papio anubis 100999094 39432 Saimiri boliviensis 101044689
9685 Felis catus 101083686 9669 Mustela putorius furo 101692645
13735 Pelodiscus sinensis 102457736 9615 Canis familiaris 480348
9598 Pan troglodytes 746195 9646 Ailuropoda melanoleuca ENSAMEG00000003105
9358 Choloepus hoffmanni ENSCHOG00000008208 10141 Cavia porcellus ENSCPOG00000005317
9361 Dasypus novemcinctus ENSDNOG00000017069 10020 Dipodomys ordii ENSDORG00000004304
9796 Equus caballus ENSECAG00000015597 9365 Erinaceus europaeus ENSEEUG00000005910
9031 Gallus gallus ENSGALG00000011870 9595 Gorilla gorilla ENSGGOG00000003957
9785 Loxodonta africana ENSLAFG00000013410 9103 Meleagris gallopavo ENSMGAG00000013552
59463 Myotis lucifugus ENSMLUG00000015244 13616 Monodelphis domestica ENSMODG00000008760
9986 Oryctolagus cuniculus ENSOCUG00000017741 30611 Otolemur garnettii ENSOGAG00000016112
9978 Ochotona princeps ENSOPRG00000007753 9601 Pongo abelii ENSPPYG00000005881
132908 Pteropus vampyrus ENSPVAG00000014497 10116 Rattus norvegicus ENSRNOG00000008292
42254 Sorex araneus ENSSARG00000011198 9823 Sus scrofa ENSSSCG00000005096
43179 Ictidomys tridecemlineatus ENSSTOG00000004833 37347 Tupaia belangeri ENSTBEG00000011941
59729 Taeniopygia guttata ENSTGUG00000012978 9478 Tarsius syrichta ENSTSYG00000001081
30538 Vicugna pacos ENSVPAG00000002395 9739 Tursiops truncatus ENSTTRG00000012558