Basic Information
Gene ID 101044689
Gene Name HIF1A
Full Name PREDICTED: hypoxia-inducible factor 1-alpha isoform 1 [Saimiriboliviensis boliviensis].
Organism Saimiri boliviensis [39432]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003924459 Pfam PF00989 IPR013767 118 173 2.10e-05 PAS fold
XP_003924459 Pfam PF08778 IPR014887 811 850 1.60e-22 HIF-1 alpha, transactivation domain, C-terminal
XP_003924459 Pfam PF11413 IPR021537 574 606 5.00e-16 Hypoxia-inducible factor, alpha subunit
XP_003924459 PRINTS PR01080 IPR001321 225 248 6.00e-47 Hypoxia-inducible factor-1 alpha
XP_003924459 PRINTS PR01080 IPR001321 384 402 6.00e-47 Hypoxia-inducible factor-1 alpha
XP_003924459 PRINTS PR01080 IPR001321 441 459 6.00e-47 Hypoxia-inducible factor-1 alpha
XP_003924459 PRINTS PR01080 IPR001321 481 501 6.00e-47 Hypoxia-inducible factor-1 alpha
XP_003924459 ProSiteProfiles PS50112 IPR000014 117 172 0.00e-00 PAS domain
XP_003924459 ProSiteProfiles PS50112 IPR000014 271 322 0.00e-00 PAS domain
XP_003924459 ProSiteProfiles PS50888 IPR011598 41 94 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003924459 SMART SM00086 IPR001610 326 369 2.60e-11 PAC motif
XP_003924459 SMART SM00091 IPR000014 111 177 1.50e-12 PAS domain
XP_003924459 SMART SM00091 IPR000014 254 320 8.20e-11 PAS domain
XP_003924459 SMART SM00353 IPR011598 47 102 2.80e-11 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003924459 SUPERFAMILY SSF47459 IPR011598 39 95 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003924459 SUPERFAMILY SSF55785 IPR000014 120 231 0.00e-00 PAS domain
XP_003924459 SUPERFAMILY SSF55785 IPR000014 266 367 0.00e-00 PAS domain
XP_003924459 TIGRFAM TIGR00229 IPR000014 124 177 5.50e-06 PAS domain
XP_003924459 TIGRFAM TIGR00229 IPR000014 273 354 2.30e-08 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003924459 PF14598 2.9e-26 PAS_11 PAS domain
XP_003924459 PF08447 9.7e-26 PAS_3 PAS fold
XP_003924459 PF08778 7.9e-23 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
XP_003924459 PF11413 2.1e-16 HIF-1 Hypoxia-inducible factor-1
XP_003924459 PF00989 1.1e-15 PAS PAS fold
XP_003924459 PF13426 1.7e-12 PAS_9 PAS domain
XP_003924459 PF08448 1.8e-07 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003924459 GO:0001666 biological_process response to hypoxia
XP_003924459 GO:0006351 biological_process transcription, DNA-templated
XP_003924459 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003924459 GO:0007165 biological_process signal transduction
XP_003924459 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_003924459 GO:0005634 cellular_component nucleus
XP_003924459 GO:0005737 cellular_component cytoplasm
XP_003924459 GO:0003677 molecular_function DNA binding
XP_003924459 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003924459 GO:0004871 molecular_function signal transducer activity
XP_003924459 GO:0035035 molecular_function histone acetyltransferase binding
XP_003924459 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100411678 8128 Oreochromis niloticus 100703737
9597 Pan paniscus 100993223 9555 Papio anubis 100999094
7029 Acyrthosiphon pisum 100167974 10224 Saccoglossus kowalevskii 100329032
9685 Felis catus 101083686 9669 Mustela putorius furo 101692645
13735 Pelodiscus sinensis 102457736 7955 Danio rerio 393202
9615 Canis familiaris 480348 9598 Pan troglodytes 746195
28377 Anolis carolinensis ENSACAG00000016205 9646 Ailuropoda melanoleuca ENSAMEG00000003105
9358 Choloepus hoffmanni ENSCHOG00000008208 10141 Cavia porcellus ENSCPOG00000005317
51511 Ciona savignyi ENSCSAVG00000005768 10020 Dipodomys ordii ENSDORG00000004304
69293 Gasterosteus aculeatus ENSGACG00000008525 9595 Gorilla gorilla ENSGGOG00000003957
9315 Macropus eugenii ENSMEUG00000003867 59463 Myotis lucifugus ENSMLUG00000015244
9978 Ochotona princeps ENSOPRG00000007753 9601 Pongo abelii ENSPPYG00000005881
132908 Pteropus vampyrus ENSPVAG00000014497 10116 Rattus norvegicus ENSRNOG00000008292
9823 Sus scrofa ENSSSCG00000005096 99883 Tetraodon nigroviridis ENSTNIG00000017339
9478 Tarsius syrichta ENSTSYG00000001081 8364 Xenopus tropicalis ENSXETG00000014449
8083 Xiphophorus maculatus 102217674 7897 Latimeria chalumnae 102348279
7668 Strongylocentrotus purpuratus 577801 7070 Tribolium castaneum 655772
9361 Dasypus novemcinctus ENSDNOG00000017069 9796 Equus caballus ENSECAG00000015597
9365 Erinaceus europaeus ENSEEUG00000005910 9031 Gallus gallus ENSGALG00000011870
8049 Gadus morhua ENSGMOG00000010900 9785 Loxodonta africana ENSLAFG00000013410
9103 Meleagris gallopavo ENSMGAG00000013552 30608 Microcebus murinus ENSMICG00000002224
13616 Monodelphis domestica ENSMODG00000008760 9258 Ornithorhynchus anatinus ENSOANG00000009092
9986 Oryctolagus cuniculus ENSOCUG00000017741 30611 Otolemur garnettii ENSOGAG00000016112
9813 Procavia capensis ENSPCAG00000011584 7757 Petromyzon marinus ENSPMAG00000000126
42254 Sorex araneus ENSSARG00000011198 43179 Ictidomys tridecemlineatus ENSSTOG00000004833
37347 Tupaia belangeri ENSTBEG00000011941 59729 Taeniopygia guttata ENSTGUG00000012978
31033 Takifugu rubripes ENSTRUG00000012093 9739 Tursiops truncatus ENSTTRG00000012558
30538 Vicugna pacos ENSVPAG00000002395