Basic Information
Gene ID 102457736
Gene Name HIF1A
Full Name Uncharacterized protein
Organism Pelodiscus sinensis [13735]

Cross Reference
UniProt K7FUG2 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPSIP00000011672 Pfam PF00989 IPR013767 87 143 1.20e-05 PAS fold
ENSPSIP00000011672 Pfam PF08778 IPR014887 764 803 2.30e-22 HIF-1 alpha, transactivation domain, C-terminal
ENSPSIP00000011672 Pfam PF11413 IPR021537 541 572 2.30e-15 Hypoxia-inducible factor, alpha subunit
ENSPSIP00000011672 PRINTS PR01080 IPR001321 194 217 9.90e-35 Hypoxia-inducible factor-1 alpha
ENSPSIP00000011672 PRINTS PR01080 IPR001321 353 371 9.90e-35 Hypoxia-inducible factor-1 alpha
ENSPSIP00000011672 PRINTS PR01080 IPR001321 408 426 9.90e-35 Hypoxia-inducible factor-1 alpha
ENSPSIP00000011672 PRINTS PR01080 IPR001321 448 468 9.90e-35 Hypoxia-inducible factor-1 alpha
ENSPSIP00000011672 ProSiteProfiles PS50112 IPR000014 240 291 0.00e-00 PAS domain
ENSPSIP00000011672 ProSiteProfiles PS50112 IPR000014 73 151 0.00e-00 PAS domain
ENSPSIP00000011672 ProSiteProfiles PS50888 IPR011598 10 63 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPSIP00000011672 SMART SM00086 IPR001610 295 338 1.60e-11 PAC motif
ENSPSIP00000011672 SMART SM00091 IPR000014 223 289 1.40e-10 PAS domain
ENSPSIP00000011672 SMART SM00091 IPR000014 80 146 1.20e-10 PAS domain
ENSPSIP00000011672 SMART SM00353 IPR011598 16 71 2.00e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPSIP00000011672 SUPERFAMILY SSF47459 IPR011598 8 67 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPSIP00000011672 SUPERFAMILY SSF55785 IPR000014 235 337 0.00e-00 PAS domain
ENSPSIP00000011672 SUPERFAMILY SSF55785 IPR000014 89 195 0.00e-00 PAS domain
ENSPSIP00000011672 TIGRFAM TIGR00229 IPR000014 242 323 3.90e-08 PAS domain
ENSPSIP00000011672 TIGRFAM TIGR00229 IPR000014 93 149 2.40e-06 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPSIP00000011672 PF14598 1.1e-26 PAS_11 PAS domain
ENSPSIP00000011672 PF08447 2.8e-25 PAS_3 PAS fold
ENSPSIP00000011672 PF08778 1.1e-22 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSPSIP00000011672 PF00989 4.1e-16 PAS PAS fold
ENSPSIP00000011672 PF11413 1e-15 HIF-1 Hypoxia-inducible factor-1
ENSPSIP00000011672 PF13426 1.8e-11 PAS_9 PAS domain
ENSPSIP00000011672 PF08448 4e-08 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPSIP00000011672 GO:0001666 biological_process response to hypoxia
ENSPSIP00000011672 GO:0006351 biological_process transcription, DNA-templated
ENSPSIP00000011672 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPSIP00000011672 GO:0007165 biological_process signal transduction
ENSPSIP00000011672 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPSIP00000011672 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSPSIP00000011672 GO:0071456 biological_process cellular response to hypoxia
ENSPSIP00000011672 GO:0005634 cellular_component nucleus
ENSPSIP00000011672 GO:0005737 cellular_component cytoplasm
ENSPSIP00000011672 GO:0003677 molecular_function DNA binding
ENSPSIP00000011672 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPSIP00000011672 GO:0004871 molecular_function signal transducer activity
ENSPSIP00000011672 GO:0035035 molecular_function histone acetyltransferase binding
ENSPSIP00000011672 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100167974 9483 Callithrix jacchus 100411678
61853 Nomascus leucogenys 100582446 8128 Oreochromis niloticus 100703737
9597 Pan paniscus 100993223 9555 Papio anubis 100999094
39432 Saimiri boliviensis 101044689 9685 Felis catus 101083686
9669 Mustela putorius furo 101692645 8083 Xiphophorus maculatus 102217674
7897 Latimeria chalumnae 102348279 10224 Saccoglossus kowalevskii 100329032
10090 Mus musculus 53417 9358 Choloepus hoffmanni ENSCHOG00000008208
10141 Cavia porcellus ENSCPOG00000005317 10020 Dipodomys ordii ENSDORG00000004304
9595 Gorilla gorilla ENSGGOG00000003957 9823 Sus scrofa ENSSSCG00000005096
7955 Danio rerio 393202 9615 Canis familiaris 480348
7668 Strongylocentrotus purpuratus 577801 7070 Tribolium castaneum 655772
9598 Pan troglodytes 746195 28377 Anolis carolinensis ENSACAG00000016205
9646 Ailuropoda melanoleuca ENSAMEG00000003105 7719 Ciona intestinalis ENSCING00000001010
51511 Ciona savignyi ENSCSAVG00000005768 9361 Dasypus novemcinctus ENSDNOG00000017069
9796 Equus caballus ENSECAG00000015597 9365 Erinaceus europaeus ENSEEUG00000005910
69293 Gasterosteus aculeatus ENSGACG00000008525 9031 Gallus gallus ENSGALG00000011870
8049 Gadus morhua ENSGMOG00000010900 9785 Loxodonta africana ENSLAFG00000013410
9315 Macropus eugenii ENSMEUG00000003867 9103 Meleagris gallopavo ENSMGAG00000013552
30608 Microcebus murinus ENSMICG00000002224 59463 Myotis lucifugus ENSMLUG00000015244
13616 Monodelphis domestica ENSMODG00000008760 9258 Ornithorhynchus anatinus ENSOANG00000009092
9986 Oryctolagus cuniculus ENSOCUG00000017741 30611 Otolemur garnettii ENSOGAG00000016112
9978 Ochotona princeps ENSOPRG00000007753 8090 Oryzias latipes ENSORLG00000002004
9813 Procavia capensis ENSPCAG00000011584 9601 Pongo abelii ENSPPYG00000005881
132908 Pteropus vampyrus ENSPVAG00000014497 10116 Rattus norvegicus ENSRNOG00000008292
42254 Sorex araneus ENSSARG00000011198 9305 Sarcophilus harrisii ENSSHAG00000004128
43179 Ictidomys tridecemlineatus ENSSTOG00000004833 37347 Tupaia belangeri ENSTBEG00000011941
59729 Taeniopygia guttata ENSTGUG00000012978 99883 Tetraodon nigroviridis ENSTNIG00000017339
31033 Takifugu rubripes ENSTRUG00000012093 9478 Tarsius syrichta ENSTSYG00000001081
9739 Tursiops truncatus ENSTTRG00000012558 30538 Vicugna pacos ENSVPAG00000002395
8364 Xenopus tropicalis ENSXETG00000014449