Basic Information
Gene ID ENSPPYG00000014762
Gene Name CLOCK
Full Name Circadian locomoter output cycles protein kaput
Organism Pongo abelii [9601]

Cross Reference
UniProt H2PDD8 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000016487 Gene3D G3DSA:4.10.280.10 IPR011598 35 85 5.70e-12 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016487 Pfam PF00010 IPR011598 35 83 4.80e-09 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016487 Pfam PF00989 IPR013767 110 176 7.60e-08 PAS fold
ENSPPYP00000016487 PRINTS PR00785 IPR001067 100 123 2.30e-12 Nuclear translocator
ENSPPYP00000016487 PRINTS PR00785 IPR001067 275 292 2.30e-12 Nuclear translocator
ENSPPYP00000016487 PRINTS PR00785 IPR001067 49 64 2.30e-12 Nuclear translocator
ENSPPYP00000016487 ProSiteProfiles PS50112 IPR000014 107 177 0.00e-00 PAS domain
ENSPPYP00000016487 ProSiteProfiles PS50112 IPR000014 285 332 0.00e-00 PAS domain
ENSPPYP00000016487 ProSiteProfiles PS50888 IPR011598 34 84 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016487 SMART SM00086 IPR001610 336 379 3.00e-09 PAC motif
ENSPPYP00000016487 SMART SM00091 IPR000014 109 175 7.50e-09 PAS domain
ENSPPYP00000016487 SMART SM00091 IPR000014 264 330 1.40e-06 PAS domain
ENSPPYP00000016487 SMART SM00353 IPR011598 40 90 4.10e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016487 SUPERFAMILY SSF47459 IPR011598 31 104 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPPYP00000016487 SUPERFAMILY SSF55785 IPR000014 118 185 0.00e-00 PAS domain
ENSPPYP00000016487 SUPERFAMILY SSF55785 IPR000014 274 376 0.00e-00 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000016487 PF14598 2.1e-24 PAS_11 PAS domain
ENSPPYP00000016487 PF08447 1.7e-15 PAS_3 PAS fold
ENSPPYP00000016487 PF00989 1.2e-10 PAS PAS fold
ENSPPYP00000016487 PF00010 1.8e-09 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000016487 GO:0006351 biological_process transcription, DNA-templated
ENSPPYP00000016487 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPPYP00000016487 GO:0006974 biological_process cellular response to DNA damage stimulus
ENSPPYP00000016487 GO:0007165 biological_process signal transduction
ENSPPYP00000016487 GO:0032922 biological_process circadian regulation of gene expression
ENSPPYP00000016487 GO:0048511 biological_process rhythmic process
ENSPPYP00000016487 GO:0005634 cellular_component nucleus
ENSPPYP00000016487 GO:0005667 cellular_component transcription factor complex
ENSPPYP00000016487 GO:0005694 cellular_component chromosome
ENSPPYP00000016487 GO:0005737 cellular_component cytoplasm
ENSPPYP00000016487 GO:0001047 molecular_function core promoter binding
ENSPPYP00000016487 GO:0003677 molecular_function DNA binding
ENSPPYP00000016487 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPPYP00000016487 GO:0004402 molecular_function histone acetyltransferase activity
ENSPPYP00000016487 GO:0004871 molecular_function signal transducer activity
ENSPPYP00000016487 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100349684 8128 Oreochromis niloticus 100690629
39432 Saimiri boliviensis 101035173 9685 Felis catus 101088483
9606 Homo sapiens 9575 9646 Ailuropoda melanoleuca ENSAMEG00000018420
9615 Canis familiaris ENSCAFG00000002140 9358 Choloepus hoffmanni ENSCHOG00000004103
10141 Cavia porcellus ENSCPOG00000011807 9031 Gallus gallus ENSGALG00000013793
9544 Macaca mulatta ENSMMUG00000001919 9978 Ochotona princeps ENSOPRG00000005292
7425 Nasonia vitripennis 100114103 7029 Acyrthosiphon pisum 100163752
9483 Callithrix jacchus 100407407 61853 Nomascus leucogenys 100606130
30195 Bombus terrestris 100650446 132113 Bombus impatiens 100747861
10029 Cricetulus griseus 100756929 7463 Apis florea 100869092
143995 Megachile rotundata 100878984 34638 Metaseiulus occidentalis 100900259
9597 Pan paniscus 100986920 9555 Papio anubis 101017477
9669 Mustela putorius furo 101674500 43179 Ictidomys tridecemlineatus 101958731
13735 Pelodiscus sinensis 102444504 7955 Danio rerio 352927
7227 Drosophila melanogaster 38872 7460 Apis mellifera 411534
7668 Strongylocentrotus purpuratus 576191 10116 Rattus norvegicus 60447
7070 Tribolium castaneum 655469 28377 Anolis carolinensis ENSACAG00000009335
9913 Bos taurus ENSBTAG00000044044 9361 Dasypus novemcinctus ENSDNOG00000018101
10020 Dipodomys ordii ENSDORG00000008014 9796 Equus caballus ENSECAG00000006331
9365 Erinaceus europaeus ENSEEUG00000000876 9371 Echinops telfairi ENSETEG00000015604
69293 Gasterosteus aculeatus ENSGACG00000015939 9595 Gorilla gorilla ENSGGOG00000005753
8049 Gadus morhua ENSGMOG00000004825 7897 Latimeria chalumnae ENSLACG00000013436
9785 Loxodonta africana ENSLAFG00000009558 9315 Macropus eugenii ENSMEUG00000005481
9103 Meleagris gallopavo ENSMGAG00000014799 30608 Microcebus murinus ENSMICG00000000320
59463 Myotis lucifugus ENSMLUG00000010007 13616 Monodelphis domestica ENSMODG00000001691
9258 Ornithorhynchus anatinus ENSOANG00000003801 30611 Otolemur garnettii ENSOGAG00000012464
8090 Oryzias latipes ENSORLG00000004495 9813 Procavia capensis ENSPCAG00000004689
7757 Petromyzon marinus ENSPMAG00000002704 132908 Pteropus vampyrus ENSPVAG00000008960
42254 Sorex araneus ENSSARG00000002584 9305 Sarcophilus harrisii ENSSHAG00000005555
9823 Sus scrofa ENSSSCG00000008909 37347 Tupaia belangeri ENSTBEG00000002540
59729 Taeniopygia guttata ENSTGUG00000007513 31033 Takifugu rubripes ENSTRUG00000015488
9478 Tarsius syrichta ENSTSYG00000003546 9739 Tursiops truncatus ENSTTRG00000000960
30538 Vicugna pacos ENSVPAG00000006438 8364 Xenopus tropicalis ENSXETG00000021064
8083 Xiphophorus maculatus ENSXMAG00000016928 99883 Tetraodon nigroviridis ENSTNIG00000017652