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Resources: IPC: Isoelectric Point Calculator
Submitted by Lukasz Pawel Kozlowski; posted on Sunday, June 12, 2016 (1 comment)
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The estimation of the isoelectric point (pI) based on the amino acid sequence is useful for many biochemistry and proteomics techniques such as 2D-PAGE, IEF or mass spectrometry.
Isoelectric Point Calculator allows for prediction of pI using different algorithms (17 algorithms implemented including two new ones).
IPC outperform previous algorithms by at least 14.9% for proteins and 0.9% for peptides (on average, 22.1% and 59.6%, respectively), which corresponds to an average error of the pI estimation equal to 0.87 and 0.25 pH units for proteins and peptides, respectively.
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The webserver has been moved to isoelectric.org
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