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    Opportunity: Bioinformatics Analyst II/III -- Banchereau Lab @ The Jackson Laboratory -- Farmington, CT (US)
    Submitted by Tyler Chukwu; posted on Wednesday, December 06, 2017



    The role requires a highly motivated, innovative, driven, and independent bioinformatics analyst who will perform analysis of the next generation sequencing (NGS) data generated in the Banchereau Laboratory. This is a highly collaborative environment with multiple projects in the field of Immunology and Cancer. Analyst is expected to collaborate, integrate, and communicate with the bench scientists conducting the experiments and generating the data. Major tasks include running and improving analytical pipelines to process transcriptomics (RNA-seq and Pacbio ISO-seq data) as well as epigenomics datasets (ATAC-seq) in a high performance computing environment (cluster). Role will be directly supervised. Manager will determine assignment and prioritization of projects, as well as assessment of progress on projects, in direct consultation with analyst.


    Key Responsibilities:
    • Processing, visualization, and analysis of transcriptomics datasets, including Illumina RNA-seq and Pacbio ISO-seq long-read technology (60%)
    • Processing and analysis of epigenomics datasets generated by ATAC-seq (20%)
    • Implementing and running tools/packages for differential transcriptome and alternative splicing analyses in large in-house and public datasets, including TCGA (10%)
    • Arrange and deposit NGS data to appropriate public repositories (e.g., dbGaP, GEO, etc.) upon manuscript acceptance/publication (5%)
    • Implementing and/or developing publically-accessible databases to share Lab data and results with the biomedical research communities (5%)


    • Level II requires MS or PhD degree in Bioinformatics or relevant biological sciences degree. Incumbents who have not achieved a PhD may compensate with a Master's degree and at least five years of professional work experience in bioinformatics. Works with limited supervision for tasks performed.
    • Level III requires MS or PhD degree in Bioinformatics or relevant biological sciences degree. Incumbents who have not achieved the PhD level will have at least seven years profession work experience in the bioinformatics domain. Incumbents with a PhD will have completed a bioinformatics postdoctoral fellowship and/or have a minimum of two years of professional work experience in the bioinformatics domain.
    • Proficiency in R and Python programming languages
    • Strong knowledge of UNIX and shell programming
    • Previous experience in analyzing next generation sequencing datasets (e.g. RNA-seq, ATAC-seq, ChIP-seq)
    • Capable of performing analysis in a high performance computing environment (cluster)
    • Preferred: Experience in Pacbio long-read sequencing datasets, especially in ISO-seq
    • Preferred: Knowledge in immunology and cancer research


    What do we have to offer?
    JAX offers a dynamic and supportive work environment, competitive salaries and a comprehensive benefits package including a medical plan, outstanding retirement plan, generous paid time off and tuition reimbursement. JAX offers an MBA program, a fitness center with an award winning wellness program, and a fully operational primary care facility available to employees and their families.


    The Jackson Laboratory ( is a nonprofit biomedical research institute with over 1,800 employees across three campuses nationwide. Our mission is to discover precise genomic solutions for human disease, and to empower the global biomedical community in the shared quest to improve human health. JAX's research institute in Connecticut, The Jackson Laboratory for Genomic Medicine (JAX-GM), is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX-GM's research focuses on the complex genetic causes of disease, and on the development of genomic solutions tailored to each person's unique genetic makeup.

    JAX-GM sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians and support staff in state-of-the-art computing facilities and laboratories. Our employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients' lives.

    JAX-GM resides in the scenic town of Farmington, in the state's capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX-GM is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems including bus lines, highways, railroads and international airports.

    Our Values:
    INTEGRITY – Courage and commitment to do what is right
    PEOPLE – Inspiring our people to enhance the health of all
    ONE TEAM – Unified by our promise to transform medicine and science
    EXCELLENCE – Achieving world-class results
    INNOVATION – Leading with discovery and creative solutions
    STEWARDSHIP – Caring for and enhancing the resources entrusted to us

    Most importantly, every position contributes to JAX's mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.




    The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

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