Basic Information
Gene ID 397340
Gene Name STAT5B
Full Name Signal transducer and activator of transcription 5B
Organism Sus scrofa [9823]

Cross Reference
UniProt Q9TUZ0 UniGene Ssc.16047
PDB NULL OMIM NULL
KEGG ssc:397340 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSSCP00000018443 Gene3D G3DSA:1.10.238.10 IPR011992 472 597 9.80e-48 EF-hand domain pair
ENSSSCP00000018443 Gene3D G3DSA:1.10.532.10 IPR013799 1 125 5.00e-49 STAT transcription factor, protein interaction
ENSSSCP00000018443 Gene3D G3DSA:1.20.1050.20 IPR013800 139 332 3.80e-65 STAT transcription factor, all-alpha
ENSSSCP00000018443 Gene3D G3DSA:2.60.40.630 IPR012345 333 471 6.80e-69 STAT transcription factor, DNA-binding, subdomain
ENSSSCP00000018443 Gene3D G3DSA:3.30.505.10 IPR000980 598 712 6.70e-41 SH2 domain
ENSSSCP00000018443 PANTHER PTHR11801 IPR001217 2 779 0.00e-00 Transcription factor STAT
ENSSSCP00000018443 Pfam PF00017 IPR000980 595 667 1.80e-10 SH2 domain
ENSSSCP00000018443 Pfam PF01017 IPR013800 138 330 2.20e-55 STAT transcription factor, all-alpha
ENSSSCP00000018443 Pfam PF02864 IPR013801 332 583 4.30e-99 STAT transcription factor, DNA-binding
ENSSSCP00000018443 Pfam PF02865 IPR013799 2 125 1.80e-48 STAT transcription factor, protein interaction
ENSSSCP00000018443 ProSiteProfiles PS50001 IPR000980 589 686 0.00e-00 SH2 domain
ENSSSCP00000018443 SMART SM00252 IPR000980 587 705 5.80e-08 SH2 domain
ENSSSCP00000018443 SMART SM00964 IPR013799 2 126 3.20e-66 STAT transcription factor, protein interaction
ENSSSCP00000018443 SUPERFAMILY SSF47655 IPR015988 136 332 0.00e-00 STAT transcription factor, coiled coil
ENSSSCP00000018443 SUPERFAMILY SSF48092 IPR013799 1 124 0.00e-00 STAT transcription factor, protein interaction
ENSSSCP00000018443 SUPERFAMILY SSF49417 IPR008967 327 584 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSSCP00000018443 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSSSCP00000018443 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSSSCP00000018443 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSSSCP00000018443 PF00017 2.2e-12 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSSCP00000018443 GO:0001553 biological_process luteinization
ENSSSCP00000018443 GO:0001779 biological_process natural killer cell differentiation
ENSSSCP00000018443 GO:0006351 biological_process transcription, DNA-templated
ENSSSCP00000018443 GO:0007259 biological_process JAK-STAT cascade
ENSSSCP00000018443 GO:0007565 biological_process female pregnancy
ENSSSCP00000018443 GO:0007595 biological_process lactation
ENSSSCP00000018443 GO:0019218 biological_process regulation of steroid metabolic process
ENSSSCP00000018443 GO:0019915 biological_process lipid storage
ENSSSCP00000018443 GO:0030155 biological_process regulation of cell adhesion
ENSSSCP00000018443 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSSSCP00000018443 GO:0038161 biological_process prolactin signaling pathway
ENSSSCP00000018443 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSSSCP00000018443 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSSSCP00000018443 GO:0043029 biological_process T cell homeostasis
ENSSSCP00000018443 GO:0043066 biological_process negative regulation of apoptotic process
ENSSSCP00000018443 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSSSCP00000018443 GO:0045579 biological_process positive regulation of B cell differentiation
ENSSSCP00000018443 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSSSCP00000018443 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSSSCP00000018443 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSSSCP00000018443 GO:0046543 biological_process development of secondary female sexual characteristics
ENSSSCP00000018443 GO:0050729 biological_process positive regulation of inflammatory response
ENSSSCP00000018443 GO:0005634 cellular_component nucleus
ENSSSCP00000018443 GO:0005737 cellular_component cytoplasm
ENSSSCP00000018443 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSSCP00000018443 GO:0004871 molecular_function signal transducer activity
ENSSSCP00000018443 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100121885 7029 Acyrthosiphon pisum 100161101
9986 Oryctolagus cuniculus 100348267 9601 Pongo abelii 100462537
400682 Amphimedon queenslandica 100641588 30195 Bombus terrestris 100647789
132113 Bombus impatiens 100743540 10029 Cricetulus griseus 100755571
7463 Apis florea 100864112 143995 Megachile rotundata 100880948
34638 Metaseiulus occidentalis 100904925 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100989105 9555 Papio anubis 101000002
39432 Saimiri boliviensis 101043203 9669 Mustela putorius furo 101691575
10090 Mus musculus 20851 10116 Rattus norvegicus 25126
9031 Gallus gallus 395556 7460 Apis mellifera 413742
7227 Drosophila melanogaster 42428 9598 Pan troglodytes 454681
9544 Macaca mulatta 574129 7668 Strongylocentrotus purpuratus 576433
7070 Tribolium castaneum 657965 7719 Ciona intestinalis 778770
9646 Ailuropoda melanoleuca ENSAMEG00000006061 9913 Bos taurus ENSBTAG00000009496
9615 Canis familiaris ENSCAFG00000015509 9358 Choloepus hoffmanni ENSCHOG00000005387
9483 Callithrix jacchus ENSCJAG00000000426 10141 Cavia porcellus ENSCPOG00000026466
51511 Ciona savignyi ENSCSAVG00000011110 7955 Danio rerio ENSDARG00000019392
9361 Dasypus novemcinctus ENSDNOG00000007398 10020 Dipodomys ordii ENSDORG00000000303
9796 Equus caballus ENSECAG00000007847 9365 Erinaceus europaeus ENSEEUG00000003642
9371 Echinops telfairi ENSETEG00000008535 9685 Felis catus ENSFCAG00000028112
69293 Gasterosteus aculeatus ENSGACG00000008634 9595 Gorilla gorilla ENSGGOG00000008216
8049 Gadus morhua ENSGMOG00000014154 7897 Latimeria chalumnae ENSLACG00000002646
9785 Loxodonta africana ENSLAFG00000014055 9315 Macropus eugenii ENSMEUG00000006640
9103 Meleagris gallopavo ENSMGAG00000003430 30608 Microcebus murinus ENSMICG00000011988
59463 Myotis lucifugus ENSMLUG00000012050 13616 Monodelphis domestica ENSMODG00000014836
61853 Nomascus leucogenys ENSNLEG00000011444 9258 Ornithorhynchus anatinus ENSOANG00000006496
8128 Oreochromis niloticus ENSONIG00000007261 9978 Ochotona princeps ENSOPRG00000008312
8090 Oryzias latipes ENSORLG00000003961 9813 Procavia capensis ENSPCAG00000010107
7757 Petromyzon marinus ENSPMAG00000009008 13735 Pelodiscus sinensis ENSPSIG00000015138
132908 Pteropus vampyrus ENSPVAG00000003876 42254 Sorex araneus ENSSARG00000014229
43179 Ictidomys tridecemlineatus ENSSTOG00000006691 37347 Tupaia belangeri ENSTBEG00000009608
59729 Taeniopygia guttata ENSTGUG00000002572 99883 Tetraodon nigroviridis ENSTNIG00000011707
31033 Takifugu rubripes ENSTRUG00000015454 9739 Tursiops truncatus ENSTTRG00000006684
30538 Vicugna pacos ENSVPAG00000005450 8364 Xenopus tropicalis ENSXETG00000000836
8083 Xiphophorus maculatus ENSXMAG00000005165

Paralogs
ENSSSCG00000017402 ENSSSCG00000017408 ENSSSCG00000025249