Basic Information
Gene ID ENSMODG00000014836
Gene Name STAT5B
Full Name Signal transducer and activator of transcription
Organism Monodelphis domestica [13616]

Cross Reference
UniProt F7D2D3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMODP00000018532 Gene3D G3DSA:1.10.238.10 IPR011992 484 609 1.10e-47 EF-hand domain pair
ENSMODP00000018532 Gene3D G3DSA:1.10.532.10 IPR013799 13 138 6.80e-48 STAT transcription factor, protein interaction
ENSMODP00000018532 Gene3D G3DSA:1.20.1050.20 IPR013800 151 344 2.80e-64 STAT transcription factor, all-alpha
ENSMODP00000018532 Gene3D G3DSA:2.60.40.630 IPR012345 345 483 6.20e-69 STAT transcription factor, DNA-binding, subdomain
ENSMODP00000018532 Gene3D G3DSA:3.30.505.10 IPR000980 610 723 2.50e-40 SH2 domain
ENSMODP00000018532 PANTHER PTHR11801 IPR001217 14 791 0.00e-00 Transcription factor STAT
ENSMODP00000018532 Pfam PF00017 IPR000980 607 679 1.90e-10 SH2 domain
ENSMODP00000018532 Pfam PF01017 IPR013800 150 342 7.10e-55 STAT transcription factor, all-alpha
ENSMODP00000018532 Pfam PF02864 IPR013801 344 595 1.00e-98 STAT transcription factor, DNA-binding
ENSMODP00000018532 Pfam PF02865 IPR013799 14 137 2.90e-47 STAT transcription factor, protein interaction
ENSMODP00000018532 ProSiteProfiles PS50001 IPR000980 601 698 0.00e-00 SH2 domain
ENSMODP00000018532 SMART SM00252 IPR000980 599 717 1.30e-07 SH2 domain
ENSMODP00000018532 SMART SM00964 IPR013799 14 138 1.10e-64 STAT transcription factor, protein interaction
ENSMODP00000018532 SUPERFAMILY SSF47655 IPR015988 149 344 0.00e-00 STAT transcription factor, coiled coil
ENSMODP00000018532 SUPERFAMILY SSF48092 IPR013799 13 137 0.00e-00 STAT transcription factor, protein interaction
ENSMODP00000018532 SUPERFAMILY SSF49417 IPR008967 339 596 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMODP00000018532 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSMODP00000018532 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSMODP00000018532 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSMODP00000018532 PF00017 1.9e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMODP00000018532 GO:0001553 biological_process luteinization
ENSMODP00000018532 GO:0001779 biological_process natural killer cell differentiation
ENSMODP00000018532 GO:0006351 biological_process transcription, DNA-templated
ENSMODP00000018532 GO:0007259 biological_process JAK-STAT cascade
ENSMODP00000018532 GO:0007565 biological_process female pregnancy
ENSMODP00000018532 GO:0007595 biological_process lactation
ENSMODP00000018532 GO:0019218 biological_process regulation of steroid metabolic process
ENSMODP00000018532 GO:0019915 biological_process lipid storage
ENSMODP00000018532 GO:0030155 biological_process regulation of cell adhesion
ENSMODP00000018532 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSMODP00000018532 GO:0038161 biological_process prolactin signaling pathway
ENSMODP00000018532 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSMODP00000018532 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSMODP00000018532 GO:0043029 biological_process T cell homeostasis
ENSMODP00000018532 GO:0043066 biological_process negative regulation of apoptotic process
ENSMODP00000018532 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSMODP00000018532 GO:0045579 biological_process positive regulation of B cell differentiation
ENSMODP00000018532 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSMODP00000018532 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSMODP00000018532 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMODP00000018532 GO:0046543 biological_process development of secondary female sexual characteristics
ENSMODP00000018532 GO:0050729 biological_process positive regulation of inflammatory response
ENSMODP00000018532 GO:0005634 cellular_component nucleus
ENSMODP00000018532 GO:0005737 cellular_component cytoplasm
ENSMODP00000018532 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMODP00000018532 GO:0004871 molecular_function signal transducer activity
ENSMODP00000018532 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
400682 Amphimedon queenslandica 100641588 30195 Bombus terrestris 100647789
132113 Bombus impatiens 100743540 7463 Apis florea 100864112
143995 Megachile rotundata 100880948 34638 Metaseiulus occidentalis 100907258
9597 Pan paniscus 100989105 9555 Papio anubis 101000002
39432 Saimiri boliviensis 101043203 7460 Apis mellifera 413742
7227 Drosophila melanogaster 42428 7668 Strongylocentrotus purpuratus 576433
7719 Ciona intestinalis 778770 9615 Canis familiaris ENSCAFG00000015509
51511 Ciona savignyi ENSCSAVG00000011110 9361 Dasypus novemcinctus ENSDNOG00000007398
9371 Echinops telfairi ENSETEG00000008535 9595 Gorilla gorilla ENSGGOG00000008216
30608 Microcebus murinus ENSMICG00000011988 10090 Mus musculus 20851
9823 Sus scrofa 397340 9358 Choloepus hoffmanni ENSCHOG00000005387
43179 Ictidomys tridecemlineatus ENSSTOG00000006691 9258 Ornithorhynchus anatinus ENSOANG00000006496
8090 Oryzias latipes ENSORLG00000003961 37347 Tupaia belangeri ENSTBEG00000009608
30538 Vicugna pacos ENSVPAG00000005450

Paralogs
100012174