Basic Information | |||
Gene ID | ENSOANG00000006496 | ||
Gene Name | NULL | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Ornithorhynchus anatinus [9258] |
Cross Reference | |||
UniProt | F6PFX1 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSOANP00000010371 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 479 | 605 | 2.60e-47 | EF-hand domain pair |
ENSOANP00000010371 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 12 | 137 | 3.60e-38 | STAT transcription factor, protein interaction |
ENSOANP00000010371 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 150 | 239 | 4.10e-13 | STAT transcription factor, all-alpha |
ENSOANP00000010371 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 340 | 478 | 5.80e-69 | STAT transcription factor, DNA-binding, subdomain |
ENSOANP00000010371 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 606 | 720 | 1.20e-40 | SH2 domain |
ENSOANP00000010371 | PANTHER | PTHR11801 | IPR001217 | 13 | 755 | 0.00e-00 | Transcription factor STAT |
ENSOANP00000010371 | Pfam | PF00017 | IPR000980 | 603 | 675 | 1.90e-10 | SH2 domain |
ENSOANP00000010371 | Pfam | PF01017 | IPR013800 | 149 | 238 | 1.90e-09 | STAT transcription factor, all-alpha |
ENSOANP00000010371 | Pfam | PF02864 | IPR013801 | 339 | 591 | 1.90e-98 | STAT transcription factor, DNA-binding |
ENSOANP00000010371 | Pfam | PF02865 | IPR013799 | 13 | 136 | 9.90e-39 | STAT transcription factor, protein interaction |
ENSOANP00000010371 | ProSiteProfiles | PS50001 | IPR000980 | 597 | 694 | 0.00e-00 | SH2 domain |
ENSOANP00000010371 | SMART | SM00252 | IPR000980 | 595 | 696 | 3.60e-07 | SH2 domain |
ENSOANP00000010371 | SMART | SM00964 | IPR013799 | 13 | 137 | 3.50e-58 | STAT transcription factor, protein interaction |
ENSOANP00000010371 | SUPERFAMILY | SSF47655 | IPR015988 | 147 | 225 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSOANP00000010371 | SUPERFAMILY | SSF48092 | IPR013799 | 12 | 136 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSOANP00000010371 | SUPERFAMILY | SSF49417 | IPR008967 | 334 | 592 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSOANP00000010371 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSOANP00000010371 | PF02865 | 9.9e-39 | STAT_int | STAT protein, protein interaction domain |
ENSOANP00000010371 | PF00017 | 1.6e-11 | SH2 | SH2 domain |
ENSOANP00000010371 | PF01017 | 1.8e-10 | STAT_alpha | STAT protein, all-alpha domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSOANP00000010371 | GO:0001553 | biological_process | luteinization |
ENSOANP00000010371 | GO:0001779 | biological_process | natural killer cell differentiation |
ENSOANP00000010371 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSOANP00000010371 | GO:0007259 | biological_process | JAK-STAT cascade |
ENSOANP00000010371 | GO:0007565 | biological_process | female pregnancy |
ENSOANP00000010371 | GO:0007595 | biological_process | lactation |
ENSOANP00000010371 | GO:0019218 | biological_process | regulation of steroid metabolic process |
ENSOANP00000010371 | GO:0019915 | biological_process | lipid storage |
ENSOANP00000010371 | GO:0030155 | biological_process | regulation of cell adhesion |
ENSOANP00000010371 | GO:0030856 | biological_process | regulation of epithelial cell differentiation |
ENSOANP00000010371 | GO:0038161 | biological_process | prolactin signaling pathway |
ENSOANP00000010371 | GO:0040018 | biological_process | positive regulation of multicellular organism growth |
ENSOANP00000010371 | GO:0042104 | biological_process | positive regulation of activated T cell proliferation |
ENSOANP00000010371 | GO:0043029 | biological_process | T cell homeostasis |
ENSOANP00000010371 | GO:0043066 | biological_process | negative regulation of apoptotic process |
ENSOANP00000010371 | GO:0045086 | biological_process | positive regulation of interleukin-2 biosynthetic process |
ENSOANP00000010371 | GO:0045579 | biological_process | positive regulation of B cell differentiation |
ENSOANP00000010371 | GO:0045647 | biological_process | negative regulation of erythrocyte differentiation |
ENSOANP00000010371 | GO:0045931 | biological_process | positive regulation of mitotic cell cycle |
ENSOANP00000010371 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
ENSOANP00000010371 | GO:0046543 | biological_process | development of secondary female sexual characteristics |
ENSOANP00000010371 | GO:0050729 | biological_process | positive regulation of inflammatory response |
ENSOANP00000010371 | GO:0005634 | cellular_component | nucleus |
ENSOANP00000010371 | GO:0005737 | cellular_component | cytoplasm |
ENSOANP00000010371 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSOANP00000010371 | GO:0004871 | molecular_function | signal transducer activity |
ENSOANP00000010371 | GO:0005509 | molecular_function | calcium ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
39432 | Saimiri boliviensis | 101043203 | 9685 | Felis catus | ENSFCAG00000028112 |
7897 | Latimeria chalumnae | ENSLACG00000002646 | 7425 | Nasonia vitripennis | 100121885 |
7029 | Acyrthosiphon pisum | 100161101 | 6087 | Hydra magnipapillata | 100206878 |
9986 | Oryctolagus cuniculus | 100348267 | 9601 | Pongo abelii | 100462537 |
400682 | Amphimedon queenslandica | 100641588 | 30195 | Bombus terrestris | 100647789 |
132113 | Bombus impatiens | 100743540 | 10029 | Cricetulus griseus | 100755571 |
7463 | Apis florea | 100864112 | 143995 | Megachile rotundata | 100880948 |
34638 | Metaseiulus occidentalis | 100907258 | 30611 | Otolemur garnettii | 100958999 |
9597 | Pan paniscus | 100989105 | 9555 | Papio anubis | 101000002 |
9669 | Mustela putorius furo | 101691575 | 10090 | Mus musculus | 20851 |
10116 | Rattus norvegicus | 25126 | 9031 | Gallus gallus | 395556 |
9823 | Sus scrofa | 397340 | 7460 | Apis mellifera | 413742 |
7227 | Drosophila melanogaster | 42428 | 9544 | Macaca mulatta | 574129 |
7668 | Strongylocentrotus purpuratus | 576433 | 7070 | Tribolium castaneum | 657965 |
7719 | Ciona intestinalis | 778770 | 28377 | Anolis carolinensis | ENSACAG00000009680 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000006061 | 9913 | Bos taurus | ENSBTAG00000009496 |
9615 | Canis familiaris | ENSCAFG00000015509 | 9358 | Choloepus hoffmanni | ENSCHOG00000005387 |
9483 | Callithrix jacchus | ENSCJAG00000000426 | 10141 | Cavia porcellus | ENSCPOG00000026466 |
51511 | Ciona savignyi | ENSCSAVG00000011110 | 7955 | Danio rerio | ENSDARG00000019392 |
9361 | Dasypus novemcinctus | ENSDNOG00000007398 | 10020 | Dipodomys ordii | ENSDORG00000000303 |
9796 | Equus caballus | ENSECAG00000007847 | 9365 | Erinaceus europaeus | ENSEEUG00000003642 |
9371 | Echinops telfairi | ENSETEG00000008528 | 69293 | Gasterosteus aculeatus | ENSGACG00000008634 |
9595 | Gorilla gorilla | ENSGGOG00000008216 | 8049 | Gadus morhua | ENSGMOG00000014154 |
9785 | Loxodonta africana | ENSLAFG00000014055 | 9315 | Macropus eugenii | ENSMEUG00000006640 |
9103 | Meleagris gallopavo | ENSMGAG00000003430 | 30608 | Microcebus murinus | ENSMICG00000011988 |
59463 | Myotis lucifugus | ENSMLUG00000012050 | 13616 | Monodelphis domestica | ENSMODG00000014836 |
61853 | Nomascus leucogenys | ENSNLEG00000011444 | 8128 | Oreochromis niloticus | ENSONIG00000007261 |
9978 | Ochotona princeps | ENSOPRG00000008312 | 8090 | Oryzias latipes | ENSORLG00000003961 |
9813 | Procavia capensis | ENSPCAG00000010107 | 13735 | Pelodiscus sinensis | ENSPSIG00000015138 |
9598 | Pan troglodytes | ENSPTRG00000009198 | 132908 | Pteropus vampyrus | ENSPVAG00000003876 |
42254 | Sorex araneus | ENSSARG00000014205 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000006713 |
37347 | Tupaia belangeri | ENSTBEG00000009608 | 59729 | Taeniopygia guttata | ENSTGUG00000002572 |
99883 | Tetraodon nigroviridis | ENSTNIG00000011707 | 31033 | Takifugu rubripes | ENSTRUG00000015454 |
9478 | Tarsius syrichta | ENSTSYG00000000267 | 9739 | Tursiops truncatus | ENSTTRG00000006684 |
30538 | Vicugna pacos | ENSVPAG00000005450 | 8364 | Xenopus tropicalis | ENSXETG00000000836 |
8083 | Xiphophorus maculatus | ENSXMAG00000005165 | 7757 | Petromyzon marinus | ENSPMAG00000009008 |