Basic Information
Gene ID ENSGACG00000008525
Gene Name hif-1a
Full Name Uncharacterized protein
Organism Gasterosteus aculeatus [69293]

Cross Reference
UniProt G3P0Z7 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGACP00000011270 Pfam PF00989 IPR013767 93 151 1.80e-06 PAS fold
ENSGACP00000011270 Pfam PF08778 IPR014887 720 758 8.90e-23 HIF-1 alpha, transactivation domain, C-terminal
ENSGACP00000011270 Pfam PF11413 IPR021537 555 588 2.50e-18 Hypoxia-inducible factor, alpha subunit
ENSGACP00000011270 ProSiteProfiles PS50112 IPR000014 262 301 0.00e-00 PAS domain
ENSGACP00000011270 ProSiteProfiles PS50112 IPR000014 81 149 0.00e-00 PAS domain
ENSGACP00000011270 ProSiteProfiles PS50888 IPR011598 16 69 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSGACP00000011270 SMART SM00086 IPR001610 305 348 3.90e-09 PAC motif
ENSGACP00000011270 SMART SM00091 IPR000014 230 299 4.00e-06 PAS domain
ENSGACP00000011270 SMART SM00091 IPR000014 88 154 1.60e-10 PAS domain
ENSGACP00000011270 SMART SM00353 IPR011598 22 74 7.80e-08 Myc-type, basic helix-loop-helix (bHLH) domain
ENSGACP00000011270 SUPERFAMILY SSF47459 IPR011598 14 73 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSGACP00000011270 SUPERFAMILY SSF55785 IPR000014 242 344 0.00e-00 PAS domain
ENSGACP00000011270 SUPERFAMILY SSF55785 IPR000014 97 203 0.00e-00 PAS domain
ENSGACP00000011270 TIGRFAM TIGR00229 IPR000014 101 157 1.10e-05 PAS domain
ENSGACP00000011270 TIGRFAM TIGR00229 IPR000014 262 332 3.50e-06 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGACP00000011270 PF14598 7.6e-25 PAS_11 PAS domain
ENSGACP00000011270 PF08778 3.7e-23 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSGACP00000011270 PF08447 3.3e-22 PAS_3 PAS fold
ENSGACP00000011270 PF11413 2.5e-18 HIF-1 Hypoxia-inducible factor-1
ENSGACP00000011270 PF00989 3.2e-14 PAS PAS fold
ENSGACP00000011270 PF13426 8.8e-09 PAS_9 PAS domain
ENSGACP00000011270 PF08448 4.9e-06 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGACP00000011270 GO:0001666 biological_process response to hypoxia
ENSGACP00000011270 GO:0006351 biological_process transcription, DNA-templated
ENSGACP00000011270 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSGACP00000011270 GO:0007165 biological_process signal transduction
ENSGACP00000011270 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSGACP00000011270 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSGACP00000011270 GO:0071456 biological_process cellular response to hypoxia
ENSGACP00000011270 GO:0005634 cellular_component nucleus
ENSGACP00000011270 GO:0005737 cellular_component cytoplasm
ENSGACP00000011270 GO:0003677 molecular_function DNA binding
ENSGACP00000011270 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSGACP00000011270 GO:0004871 molecular_function signal transducer activity
ENSGACP00000011270 GO:0035035 molecular_function histone acetyltransferase binding
ENSGACP00000011270 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100167974 9483 Callithrix jacchus 100411678
8128 Oreochromis niloticus 100703737 9597 Pan paniscus 100993223
9555 Papio anubis 100999094 39432 Saimiri boliviensis 101044689
9685 Felis catus 101083686 8083 Xiphophorus maculatus 102217674
7897 Latimeria chalumnae 102348279 7955 Danio rerio 393202
9615 Canis familiaris 480348 7668 Strongylocentrotus purpuratus 577801
7070 Tribolium castaneum 655772 9598 Pan troglodytes 746195
28377 Anolis carolinensis ENSACAG00000016205 9646 Ailuropoda melanoleuca ENSAMEG00000003105
51511 Ciona savignyi ENSCSAVG00000005768 9361 Dasypus novemcinctus ENSDNOG00000017069
9796 Equus caballus ENSECAG00000015597 9365 Erinaceus europaeus ENSEEUG00000005910
10224 Saccoglossus kowalevskii 100329032 9669 Mustela putorius furo 101692645
13735 Pelodiscus sinensis 102457736 9358 Choloepus hoffmanni ENSCHOG00000008208
10141 Cavia porcellus ENSCPOG00000005317 10020 Dipodomys ordii ENSDORG00000004304
9595 Gorilla gorilla ENSGGOG00000003957 9823 Sus scrofa ENSSSCG00000005096
9031 Gallus gallus ENSGALG00000011870 8049 Gadus morhua ENSGMOG00000010900
9785 Loxodonta africana ENSLAFG00000013410 9103 Meleagris gallopavo ENSMGAG00000013552
30608 Microcebus murinus ENSMICG00000002224 59463 Myotis lucifugus ENSMLUG00000015244
13616 Monodelphis domestica ENSMODG00000008760 9986 Oryctolagus cuniculus ENSOCUG00000017741
30611 Otolemur garnettii ENSOGAG00000016112 9978 Ochotona princeps ENSOPRG00000007753
7757 Petromyzon marinus ENSPMAG00000000126 9601 Pongo abelii ENSPPYG00000005881
132908 Pteropus vampyrus ENSPVAG00000014497 10116 Rattus norvegicus ENSRNOG00000008292
42254 Sorex araneus ENSSARG00000011198 9305 Sarcophilus harrisii ENSSHAG00000004128
43179 Ictidomys tridecemlineatus ENSSTOG00000004833 37347 Tupaia belangeri ENSTBEG00000011941
59729 Taeniopygia guttata ENSTGUG00000012978 99883 Tetraodon nigroviridis ENSTNIG00000017339
31033 Takifugu rubripes ENSTRUG00000012093 9478 Tarsius syrichta ENSTSYG00000001081
9739 Tursiops truncatus ENSTTRG00000012558 30538 Vicugna pacos ENSVPAG00000002395
8364 Xenopus tropicalis ENSXETG00000014449