Basic Information
Gene ID ENSGALG00000025740
Gene Name EN1
Full Name Homeobox protein engrailed
Organism Gallus gallus [9031]

Cross Reference
UniProt R4GGY4 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGALP00000041310 Gene3D G3DSA:1.10.10.60 IPR009057 33 109 1.00e-25 Homeodomain-like
ENSGALP00000041310 Pfam PF00046 IPR001356 52 108 3.30e-22 Homeobox domain
ENSGALP00000041310 Pfam PF10525 IPR019549 109 140 7.60e-20 Homeobox engrailed, C-terminal
ENSGALP00000041310 PRINTS PR00024 IPR020479 73 84 6.30e-07 Homeodomain, metazoa
ENSGALP00000041310 PRINTS PR00024 IPR020479 88 98 6.30e-07 Homeodomain, metazoa
ENSGALP00000041310 PRINTS PR00024 IPR020479 98 107 6.30e-07 Homeodomain, metazoa
ENSGALP00000041310 PRINTS PR00026 IPR000747 113 130 1.00e-18 Homeodomain engrailed
ENSGALP00000041310 PRINTS PR00026 IPR000747 50 67 1.00e-18 Homeodomain engrailed
ENSGALP00000041310 PRINTS PR00031 IPR000047 80 89 6.10e-05 Helix-turn-helix motif
ENSGALP00000041310 PRINTS PR00031 IPR000047 89 105 6.10e-05 Helix-turn-helix motif
ENSGALP00000041310 ProSitePatterns PS00027 IPR017970 84 107 - Homeobox, conserved site
ENSGALP00000041310 ProSitePatterns PS00033 IPR019737 120 127 - Homeobox engrailed-type, conserved site
ENSGALP00000041310 ProSiteProfiles PS50071 IPR001356 49 109 0.00e-00 Homeobox domain
ENSGALP00000041310 SMART SM00389 IPR001356 51 113 3.70e-27 Homeobox domain
ENSGALP00000041310 SUPERFAMILY SSF46689 IPR009057 49 109 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGALP00000041310 PF00046 2.1e-22 Homeobox Homeobox domain
ENSGALP00000041310 PF10525 4.5e-20 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain
ENSGALP00000041310 PF10078 0.00092 DUF2316 Uncharacterized protein conserved in bacteria (DUF2316)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGALP00000041310 GO:0007275 biological_process multicellular organismal development
ENSGALP00000041310 GO:0005634 cellular_component nucleus
ENSGALP00000041310 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSGALP00000041310 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100303466 30195 Bombus terrestris 100649797
8128 Oreochromis niloticus 100701586 132113 Bombus impatiens 100743858
7463 Apis florea 100870890 143995 Megachile rotundata 100882481
34638 Metaseiulus occidentalis 100908620 30611 Otolemur garnettii 100946410
9597 Pan paniscus 100996220 9555 Papio anubis 101009365
7897 Latimeria chalumnae 102355550 7227 Drosophila melanogaster 36240
7719 Ciona intestinalis 445653 9544 Macaca mulatta 716307
7460 Apis mellifera 725151 9483 Callithrix jacchus ENSCJAG00000017450
10141 Cavia porcellus ENSCPOG00000014063 51511 Ciona savignyi ENSCSAVG00000008099
9796 Equus caballus ENSECAG00000000157 9365 Erinaceus europaeus ENSEEUG00000004213
69293 Gasterosteus aculeatus ENSGACG00000001508 7425 Nasonia vitripennis 100123905
7029 Acyrthosiphon pisum 100161671 9823 Sus scrofa 100512078
39432 Saimiri boliviensis 101045892 8083 Xiphophorus maculatus 102234767
9606 Homo sapiens 2020 7955 Danio rerio 541371
7668 Strongylocentrotus purpuratus 590038 7070 Tribolium castaneum 661645
28377 Anolis carolinensis ENSACAG00000001792 9646 Ailuropoda melanoleuca ENSAMEG00000008454
9913 Bos taurus ENSBTAG00000018917 9615 Canis familiaris ENSCAFG00000032481
9371 Echinops telfairi ENSETEG00000004995 9685 Felis catus ENSFCAG00000025025
9785 Loxodonta africana ENSLAFG00000026702 30608 Microcebus murinus ENSMICG00000017594
9978 Ochotona princeps ENSOPRG00000015660 9601 Pongo abelii ENSPPYG00000012793
9598 Pan troglodytes ENSPTRG00000016137 10116 Rattus norvegicus ENSRNOG00000046462
99883 Tetraodon nigroviridis ENSTNIG00000012777 9739 Tursiops truncatus ENSTTRG00000001100
8364 Xenopus tropicalis ENSXETG00000014994 9595 Gorilla gorilla ENSGGOG00000024767
8049 Gadus morhua ENSGMOG00000018280 9103 Meleagris gallopavo ENSMGAG00000012331
59463 Myotis lucifugus ENSMLUG00000008461 13616 Monodelphis domestica ENSMODG00000000438
9669 Mustela putorius furo ENSMPUG00000000896 61853 Nomascus leucogenys ENSNLEG00000011874
9258 Ornithorhynchus anatinus ENSOANG00000002989 9986 Oryctolagus cuniculus ENSOCUG00000002453
8090 Oryzias latipes ENSORLG00000010437 7757 Petromyzon marinus ENSPMAG00000010362
13735 Pelodiscus sinensis ENSPSIG00000003044 132908 Pteropus vampyrus ENSPVAG00000003106
9305 Sarcophilus harrisii ENSSHAG00000017591 43179 Ictidomys tridecemlineatus ENSSTOG00000021609
59729 Taeniopygia guttata ENSTGUG00000000695 31033 Takifugu rubripes ENSTRUG00000014340