Basic Information
Gene ID ENSOCUG00000002453
Gene Name EN2
Full Name Homeobox protein engrailed
Organism Oryctolagus cuniculus [9986]

Cross Reference
UniProt G1SHL1 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOCUP00000002121 Gene3D G3DSA:1.10.10.60 IPR009057 73 150 1.10e-27 Homeodomain-like
ENSOCUP00000002121 Pfam PF00046 IPR001356 93 149 4.00e-22 Homeobox domain
ENSOCUP00000002121 Pfam PF10525 IPR019549 150 180 7.60e-18 Homeobox engrailed, C-terminal
ENSOCUP00000002121 PRINTS PR00024 IPR020479 114 125 5.50e-07 Homeodomain, metazoa
ENSOCUP00000002121 PRINTS PR00024 IPR020479 129 139 5.50e-07 Homeodomain, metazoa
ENSOCUP00000002121 PRINTS PR00024 IPR020479 139 148 5.50e-07 Homeodomain, metazoa
ENSOCUP00000002121 PRINTS PR00026 IPR000747 154 171 2.90e-18 Homeodomain engrailed
ENSOCUP00000002121 PRINTS PR00026 IPR000747 91 108 2.90e-18 Homeodomain engrailed
ENSOCUP00000002121 PRINTS PR00031 IPR000047 121 130 8.80e-05 Helix-turn-helix motif
ENSOCUP00000002121 PRINTS PR00031 IPR000047 130 146 8.80e-05 Helix-turn-helix motif
ENSOCUP00000002121 ProSitePatterns PS00027 IPR017970 125 148 - Homeobox, conserved site
ENSOCUP00000002121 ProSitePatterns PS00033 IPR019737 161 168 - Homeobox engrailed-type, conserved site
ENSOCUP00000002121 ProSiteProfiles PS50071 IPR001356 90 150 0.00e-00 Homeobox domain
ENSOCUP00000002121 SMART SM00389 IPR001356 92 154 7.10e-28 Homeobox domain
ENSOCUP00000002121 SUPERFAMILY SSF46689 IPR009057 88 150 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOCUP00000002121 PF00046 2.6e-22 Homeobox Homeobox domain
ENSOCUP00000002121 PF10525 3.3e-18 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOCUP00000002121 GO:0005634 cellular_component nucleus
ENSOCUP00000002121 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys 100581025 8128 Oreochromis niloticus 100706716
143995 Megachile rotundata 100882481 9555 Papio anubis 101019723
7227 Drosophila melanogaster 36240 9544 Macaca mulatta 716307
7460 Apis mellifera 725151 51511 Ciona savignyi ENSCSAVG00000008099
7955 Danio rerio ENSDARG00000038868 9796 Equus caballus ENSECAG00000021744
69293 Gasterosteus aculeatus ENSGACG00000003888 9103 Meleagris gallopavo ENSMGAG00000012331
7425 Nasonia vitripennis 100123905 7029 Acyrthosiphon pisum 100161671
10224 Saccoglossus kowalevskii 100303466 9601 Pongo abelii 100459532
9823 Sus scrofa 100512078 30195 Bombus terrestris 100649797
132113 Bombus impatiens 100743858 7463 Apis florea 100870890
34638 Metaseiulus occidentalis 100908620 30611 Otolemur garnettii 100946410
9597 Pan paniscus 100996220 39432 Saimiri boliviensis 101045892
31033 Takifugu rubripes 101068755 43179 Ictidomys tridecemlineatus 101960578
8083 Xiphophorus maculatus 102234767 7897 Latimeria chalumnae 102360063
9606 Homo sapiens 2020 7719 Ciona intestinalis 445653
7668 Strongylocentrotus purpuratus 590038 7070 Tribolium castaneum 661645
28377 Anolis carolinensis ENSACAG00000011018 9646 Ailuropoda melanoleuca ENSAMEG00000001224
9913 Bos taurus ENSBTAG00000018917 9615 Canis familiaris ENSCAFG00000005082
9483 Callithrix jacchus ENSCJAG00000017450 10141 Cavia porcellus ENSCPOG00000024572
9365 Erinaceus europaeus ENSEEUG00000004213 9371 Echinops telfairi ENSETEG00000004995
9685 Felis catus ENSFCAG00000023560 9031 Gallus gallus ENSGALG00000025740
9595 Gorilla gorilla ENSGGOG00000022981 8049 Gadus morhua ENSGMOG00000004983
9785 Loxodonta africana ENSLAFG00000032115 30608 Microcebus murinus ENSMICG00000017594
59463 Myotis lucifugus ENSMLUG00000004165 13616 Monodelphis domestica ENSMODG00000004978
9669 Mustela putorius furo ENSMPUG00000009596 9258 Ornithorhynchus anatinus ENSOANG00000006149
9978 Ochotona princeps ENSOPRG00000015660 8090 Oryzias latipes ENSORLG00000010437
7757 Petromyzon marinus ENSPMAG00000010362 13735 Pelodiscus sinensis ENSPSIG00000014871
9598 Pan troglodytes ENSPTRG00000016137 10116 Rattus norvegicus ENSRNOG00000046462
9305 Sarcophilus harrisii ENSSHAG00000017591 59729 Taeniopygia guttata ENSTGUG00000000695
99883 Tetraodon nigroviridis ENSTNIG00000012777 9739 Tursiops truncatus ENSTTRG00000013702
8364 Xenopus tropicalis ENSXETG00000014994 132908 Pteropus vampyrus ENSPVAG00000003106