Basic Information
Gene ID 661645
Gene Name En; TcasGA2_TC008952
Full Name Homeobox protein engrailed
Organism Tribolium castaneum [7070]

Cross Reference
UniProt D6WQ96 UniGene Tca.4761
PDB NULL OMIM NULL
KEGG tca:661645 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_972888 Gene3D G3DSA:1.10.10.60 IPR009057 182 251 2.40e-25 Homeodomain-like
XP_972888 Pfam PF00046 IPR001356 194 250 1.60e-21 Homeobox domain
XP_972888 Pfam PF10525 IPR019549 251 278 6.80e-17 Homeobox engrailed, C-terminal
XP_972888 PRINTS PR00024 IPR020479 215 226 6.40e-07 Homeodomain, metazoa
XP_972888 PRINTS PR00024 IPR020479 230 240 6.40e-07 Homeodomain, metazoa
XP_972888 PRINTS PR00024 IPR020479 240 249 6.40e-07 Homeodomain, metazoa
XP_972888 PRINTS PR00026 IPR000747 192 209 6.30e-17 Homeodomain engrailed
XP_972888 PRINTS PR00026 IPR000747 255 272 6.30e-17 Homeodomain engrailed
XP_972888 PRINTS PR00031 IPR000047 222 231 1.60e-06 Helix-turn-helix motif
XP_972888 PRINTS PR00031 IPR000047 231 247 1.60e-06 Helix-turn-helix motif
XP_972888 ProSitePatterns PS00027 IPR017970 226 249 - Homeobox, conserved site
XP_972888 ProSitePatterns PS00033 IPR019737 262 269 - Homeobox engrailed-type, conserved site
XP_972888 ProSiteProfiles PS50071 IPR001356 191 251 0.00e-00 Homeobox domain
XP_972888 SMART SM00389 IPR001356 193 255 1.20e-27 Homeobox domain
XP_972888 SUPERFAMILY SSF46689 IPR009057 175 250 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_972888 PF00046 8.1e-22 Homeobox Homeobox domain
XP_972888 PF10525 3.7e-17 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain

Gene Ontology Annotation
Protein Entry Name Space Description
XP_972888 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_972888 GO:0007275 biological_process multicellular organismal development
XP_972888 GO:0005634 cellular_component nucleus
XP_972888 GO:0000976 molecular_function transcription regulatory region sequence-specific DNA binding
XP_972888 GO:0003677 molecular_function DNA binding
XP_972888 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_972888 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100303466 61853 Nomascus leucogenys 100581025
30195 Bombus terrestris 100649797 8128 Oreochromis niloticus 100701586
132113 Bombus impatiens 100743858 7463 Apis florea 100870890
34638 Metaseiulus occidentalis 100908620 30611 Otolemur garnettii 100946410
9597 Pan paniscus 100996220 9555 Papio anubis 101019723
8090 Oryzias latipes 101161508 7719 Ciona intestinalis 445653
7425 Nasonia vitripennis 100123905 9601 Pongo abelii 100459532
9823 Sus scrofa 100512078 39432 Saimiri boliviensis 101045892
31033 Takifugu rubripes 101069787 43179 Ictidomys tridecemlineatus 101960578
8083 Xiphophorus maculatus 102234767 9606 Homo sapiens 2020
7668 Strongylocentrotus purpuratus 590038 28377 Anolis carolinensis ENSACAG00000011018
9646 Ailuropoda melanoleuca ENSAMEG00000001224 9913 Bos taurus ENSBTAG00000018917
10141 Cavia porcellus ENSCPOG00000024572 9371 Echinops telfairi ENSETEG00000004995
30608 Microcebus murinus ENSMICG00000017594 9258 Ornithorhynchus anatinus ENSOANG00000006149
9978 Ochotona princeps ENSOPRG00000015660 10116 Rattus norvegicus ENSRNOG00000046462
99883 Tetraodon nigroviridis ENSTNIG00000012777 9739 Tursiops truncatus ENSTTRG00000013702
9544 Macaca mulatta 716307 9615 Canis familiaris ENSCAFG00000005082
9483 Callithrix jacchus ENSCJAG00000017450 51511 Ciona savignyi ENSCSAVG00000008099
7955 Danio rerio ENSDARG00000038868 9796 Equus caballus ENSECAG00000021744
9365 Erinaceus europaeus ENSEEUG00000004213 9685 Felis catus ENSFCAG00000023560
69293 Gasterosteus aculeatus ENSGACG00000014426 9031 Gallus gallus ENSGALG00000025740
9595 Gorilla gorilla ENSGGOG00000022981 8049 Gadus morhua ENSGMOG00000005154
9785 Loxodonta africana ENSLAFG00000032115 9103 Meleagris gallopavo ENSMGAG00000012331
59463 Myotis lucifugus ENSMLUG00000008461 13616 Monodelphis domestica ENSMODG00000004978
9669 Mustela putorius furo ENSMPUG00000009596 9986 Oryctolagus cuniculus ENSOCUG00000002453
13735 Pelodiscus sinensis ENSPSIG00000014871 9598 Pan troglodytes ENSPTRG00000016137
132908 Pteropus vampyrus ENSPVAG00000003106 59729 Taeniopygia guttata ENSTGUG00000000695