Basic Information
Gene ID 445653
Gene Name Ci-En; en
Full Name Homeobox protein engrailed
Organism Ciona intestinalis [7719]

Cross Reference
UniProt Q8IAC7 UniGene Cin.32867
PDB NULL OMIM NULL
KEGG cin:445653 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7719.ENSCINP00000004407

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCINP00000004407 Gene3D G3DSA:1.10.10.60 IPR009057 259 320 2.90e-21 Homeodomain-like
ENSCINP00000004407 Pfam PF00046 IPR001356 262 318 9.70e-20 Homeobox domain
ENSCINP00000004407 Pfam PF10525 IPR019549 320 342 1.20e-11 Homeobox engrailed, C-terminal
ENSCINP00000004407 PRINTS PR00026 IPR000747 260 277 4.10e-10 Homeodomain engrailed
ENSCINP00000004407 PRINTS PR00026 IPR000747 323 340 4.10e-10 Homeodomain engrailed
ENSCINP00000004407 ProSitePatterns PS00027 IPR017970 294 317 - Homeobox, conserved site
ENSCINP00000004407 ProSiteProfiles PS50071 IPR001356 259 319 0.00e-00 Homeobox domain
ENSCINP00000004407 SMART SM00389 IPR001356 261 323 8.60e-27 Homeobox domain
ENSCINP00000004407 SUPERFAMILY SSF46689 IPR009057 259 319 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCINP00000004407 PF00046 3.6e-20 Homeobox Homeobox domain
ENSCINP00000004407 PF10525 1.2e-11 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCINP00000004407 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSCINP00000004407 GO:0007275 biological_process multicellular organismal development
ENSCINP00000004407 GO:0005634 cellular_component nucleus
ENSCINP00000004407 GO:0000976 molecular_function transcription regulatory region sequence-specific DNA binding
ENSCINP00000004407 GO:0003677 molecular_function DNA binding
ENSCINP00000004407 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCINP00000004407 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8128 Oreochromis niloticus 100706716 132113 Bombus impatiens 100743858
143995 Megachile rotundata 100882481 9597 Pan paniscus 100996220
9555 Papio anubis 101019723 7897 Latimeria chalumnae 102360063
7227 Drosophila melanogaster 36240 7425 Nasonia vitripennis 100123905
7029 Acyrthosiphon pisum 100161671 10224 Saccoglossus kowalevskii 100303466
9823 Sus scrofa 100512078 30195 Bombus terrestris 100649797
7463 Apis florea 100870890 34638 Metaseiulus occidentalis 100908620
30611 Otolemur garnettii 100946410 39432 Saimiri boliviensis 101045892
8083 Xiphophorus maculatus 102234767 9606 Homo sapiens 2020
7668 Strongylocentrotus purpuratus 590038 7070 Tribolium castaneum 661645
28377 Anolis carolinensis ENSACAG00000011018 9646 Ailuropoda melanoleuca ENSAMEG00000001224
9913 Bos taurus ENSBTAG00000018917 9615 Canis familiaris ENSCAFG00000032481
9365 Erinaceus europaeus ENSEEUG00000004213 9371 Echinops telfairi ENSETEG00000004995
9685 Felis catus ENSFCAG00000023560 9031 Gallus gallus ENSGALG00000025740
9595 Gorilla gorilla ENSGGOG00000022981 9785 Loxodonta africana ENSLAFG00000032115
30608 Microcebus murinus ENSMICG00000017594 13616 Monodelphis domestica ENSMODG00000004978
9669 Mustela putorius furo ENSMPUG00000009596 9258 Ornithorhynchus anatinus ENSOANG00000006149
9978 Ochotona princeps ENSOPRG00000015660 8090 Oryzias latipes ENSORLG00000010437
7757 Petromyzon marinus ENSPMAG00000010400 9601 Pongo abelii ENSPPYG00000012793
13735 Pelodiscus sinensis ENSPSIG00000014871 9598 Pan troglodytes ENSPTRG00000016137
10116 Rattus norvegicus ENSRNOG00000046462 59729 Taeniopygia guttata ENSTGUG00000000695
99883 Tetraodon nigroviridis ENSTNIG00000012777 31033 Takifugu rubripes ENSTRUG00000014340
9739 Tursiops truncatus ENSTTRG00000001100 9544 Macaca mulatta 716307
7460 Apis mellifera 725151 9483 Callithrix jacchus ENSCJAG00000017450
10141 Cavia porcellus ENSCPOG00000014063 51511 Ciona savignyi ENSCSAVG00000008099
7955 Danio rerio ENSDARG00000014321 9796 Equus caballus ENSECAG00000021744
69293 Gasterosteus aculeatus ENSGACG00000003888 8049 Gadus morhua ENSGMOG00000004983
9103 Meleagris gallopavo ENSMGAG00000012331 59463 Myotis lucifugus ENSMLUG00000008461
61853 Nomascus leucogenys ENSNLEG00000011874 9986 Oryctolagus cuniculus ENSOCUG00000002453
132908 Pteropus vampyrus ENSPVAG00000003106 9305 Sarcophilus harrisii ENSSHAG00000017591
43179 Ictidomys tridecemlineatus ENSSTOG00000021609