Basic Information
Gene ID ENSOANG00000015561
Gene Name ESR1
Full Name Uncharacterized protein
Organism Ornithorhynchus anatinus [9258]

Cross Reference
UniProt F7E7S3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOANP00000024511 Gene3D G3DSA:1.10.565.10 IPR008946 51 296 2.40e-57 Nuclear hormone receptor, ligand-binding
ENSOANP00000024511 Pfam PF00104 IPR000536 74 165 1.40e-05 Nuclear hormone receptor, ligand-binding, core
ENSOANP00000024511 Pfam PF12743 IPR024736 302 341 5.10e-20 Oestrogen-type nuclear receptor final C-terminal domain
ENSOANP00000024511 PRINTS PR00398 IPR001723 117 133 1.60e-09 Steroid hormone receptor
ENSOANP00000024511 PRINTS PR00398 IPR001723 254 271 1.60e-09 Steroid hormone receptor
ENSOANP00000024511 PRINTS PR00398 IPR001723 96 117 1.60e-09 Steroid hormone receptor
ENSOANP00000024511 SMART SM00430 IPR000536 95 266 3.80e-09 Nuclear hormone receptor, ligand-binding, core
ENSOANP00000024511 SUPERFAMILY SSF48508 IPR008946 53 295 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOANP00000024511 PF12743 2.7e-20 ESR1_C Oestrogen-type nuclear receptor final C-terminal
ENSOANP00000024511 PF00104 1.1e-10 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOANP00000024511 GO:0006351 biological_process transcription, DNA-templated
ENSOANP00000024511 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSOANP00000024511 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
ENSOANP00000024511 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
ENSOANP00000024511 GO:0010863 biological_process positive regulation of phospholipase C activity
ENSOANP00000024511 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
ENSOANP00000024511 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
ENSOANP00000024511 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
ENSOANP00000024511 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
ENSOANP00000024511 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
ENSOANP00000024511 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSOANP00000024511 GO:0071392 biological_process cellular response to estradiol stimulus
ENSOANP00000024511 GO:0005634 cellular_component nucleus
ENSOANP00000024511 GO:0005794 cellular_component Golgi apparatus
ENSOANP00000024511 GO:0005886 cellular_component plasma membrane
ENSOANP00000024511 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOANP00000024511 GO:0003707 molecular_function steroid hormone receptor activity
ENSOANP00000024511 GO:0005496 molecular_function steroid binding
ENSOANP00000024511 GO:0008270 molecular_function zinc ion binding
ENSOANP00000024511 GO:0030284 molecular_function estrogen receptor activity
ENSOANP00000024511 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 100303417 9986 Oryctolagus cuniculus 100351261
9615 Canis familiaris 403640 9913 Bos taurus ENSBTAG00000007159
10020 Dipodomys ordii ENSDORG00000010443 9796 Equus caballus ENSECAG00000022441
9365 Erinaceus europaeus ENSEEUG00000000828 9595 Gorilla gorilla ENSGGOG00000009678
9785 Loxodonta africana ENSLAFG00000015250 9315 Macropus eugenii ENSMEUG00000003564
13616 Monodelphis domestica 100027187 9483 Callithrix jacchus 100385918
9103 Meleagris gallopavo 100542782 61853 Nomascus leucogenys 100580202
10141 Cavia porcellus 100713276 10029 Cricetulus griseus 100768474
9597 Pan paniscus 100980011 39432 Saimiri boliviensis 101034130
9669 Mustela putorius furo 101690352 13735 Pelodiscus sinensis 102456765
10090 Mus musculus 13982 9606 Homo sapiens 2099
28377 Anolis carolinensis ENSACAG00000006213 9646 Ailuropoda melanoleuca ENSAMEG00000011072
9371 Echinops telfairi ENSETEG00000006131 9685 Felis catus ENSFCAG00000031492
9031 Gallus gallus ENSGALG00000012973 30608 Microcebus murinus ENSMICG00000007592
59463 Myotis lucifugus ENSMLUG00000014181 30611 Otolemur garnettii ENSOGAG00000012580
9478 Tarsius syrichta ENSTSYG00000006280 9739 Tursiops truncatus ENSTTRG00000002996
8364 Xenopus tropicalis ENSXETG00000012364 9978 Ochotona princeps ENSOPRG00000012663
132908 Pteropus vampyrus ENSPVAG00000001923 9823 Sus scrofa ENSSSCG00000025777
43179 Ictidomys tridecemlineatus ENSSTOG00000006748 37347 Tupaia belangeri ENSTBEG00000005946
59729 Taeniopygia guttata ENSTGUG00000011249 30538 Vicugna pacos ENSVPAG00000001185