Basic Information | |||
Gene ID | 100580202 | ||
Gene Name | ESR1 | ||
Full Name | Estrogen receptor | ||
Organism | Nomascus leucogenys [61853] |
Cross Reference | |||
UniProt | G1RZN0 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSNLEP00000018707 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 239 | 269 | 4.20e-101 | Nuclear hormone receptor, ligand-binding |
ENSNLEP00000018707 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 311 | 548 | 4.20e-101 | Nuclear hormone receptor, ligand-binding |
ENSNLEP00000018707 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 185 | 238 | 9.60e-28 | Zinc finger, NHR/GATA-type |
ENSNLEP00000018707 | Pfam | PF00104 | IPR000536 | 327 | 524 | 4.60e-29 | Nuclear hormone receptor, ligand-binding, core |
ENSNLEP00000018707 | Pfam | PF00105 | IPR001628 | 184 | 252 | 2.20e-31 | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | Pfam | PF02159 | IPR001292 | 42 | 181 | 5.90e-51 | Oestrogen receptor |
ENSNLEP00000018707 | Pfam | PF12743 | IPR024736 | 552 | 595 | 3.60e-22 | Oestrogen-type nuclear receptor final C-terminal domain |
ENSNLEP00000018707 | PIRSF | PIRSF002527 | IPR024178 | 42 | 590 | 4.40e-295 | Oestrogen receptor/oestrogen-related receptor |
ENSNLEP00000018707 | PIRSF | PIRSF500101 | IPR001292 | 1 | 595 | 0.00e-00 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00047 | IPR001628 | 185 | 201 | 8.20e-17 | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | PRINTS | PR00047 | IPR001628 | 201 | 216 | 8.20e-17 | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | PRINTS | PR00047 | IPR001628 | 234 | 242 | 8.20e-17 | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | PRINTS | PR00047 | IPR001628 | 242 | 250 | 8.20e-17 | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | PRINTS | PR00398 | IPR001723 | 246 | 256 | 5.70e-27 | Steroid hormone receptor |
ENSNLEP00000018707 | PRINTS | PR00398 | IPR001723 | 349 | 370 | 5.70e-27 | Steroid hormone receptor |
ENSNLEP00000018707 | PRINTS | PR00398 | IPR001723 | 370 | 386 | 5.70e-27 | Steroid hormone receptor |
ENSNLEP00000018707 | PRINTS | PR00398 | IPR001723 | 438 | 453 | 5.70e-27 | Steroid hormone receptor |
ENSNLEP00000018707 | PRINTS | PR00398 | IPR001723 | 506 | 523 | 5.70e-27 | Steroid hormone receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 115 | 131 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 132 | 151 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 153 | 172 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 26 | 43 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 45 | 62 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 6 | 24 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 70 | 85 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | PRINTS | PR00543 | IPR001292 | 97 | 111 | 5.00e-87 | Oestrogen receptor |
ENSNLEP00000018707 | ProSitePatterns | PS00031 | IPR001628 | 185 | 211 | - | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | ProSiteProfiles | PS51030 | IPR001628 | 182 | 257 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | SMART | SM00399 | IPR001628 | 182 | 253 | 6.40e-40 | Zinc finger, nuclear hormone receptor-type |
ENSNLEP00000018707 | SMART | SM00430 | IPR000536 | 348 | 518 | 2.30e-37 | Nuclear hormone receptor, ligand-binding, core |
ENSNLEP00000018707 | SUPERFAMILY | SSF48508 | IPR008946 | 235 | 261 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
ENSNLEP00000018707 | SUPERFAMILY | SSF48508 | IPR008946 | 302 | 547 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSNLEP00000018707 | PF02159 | 0 | Oest_recep | Oestrogen receptor |
ENSNLEP00000018707 | PF00105 | 1.4e-31 | zf-C4 | Zinc finger, C4 type (two domains) |
ENSNLEP00000018707 | PF00104 | 3e-29 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
ENSNLEP00000018707 | PF12743 | 1.9e-22 | ESR1_C | Oestrogen-type nuclear receptor final C-terminal |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSNLEP00000018707 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSNLEP00000018707 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSNLEP00000018707 | GO:0007200 | biological_process | phospholipase C-activating G-protein coupled receptor signaling pathway |
ENSNLEP00000018707 | GO:0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
ENSNLEP00000018707 | GO:0010863 | biological_process | positive regulation of phospholipase C activity |
ENSNLEP00000018707 | GO:0030518 | biological_process | intracellular steroid hormone receptor signaling pathway |
ENSNLEP00000018707 | GO:0043124 | biological_process | negative regulation of I-kappaB kinase/NF-kappaB signaling |
ENSNLEP00000018707 | GO:0043433 | biological_process | negative regulation of sequence-specific DNA binding transcription factor activity |
ENSNLEP00000018707 | GO:0045429 | biological_process | positive regulation of nitric oxide biosynthetic process |
ENSNLEP00000018707 | GO:0051000 | biological_process | positive regulation of nitric-oxide synthase activity |
ENSNLEP00000018707 | GO:0051091 | biological_process | positive regulation of sequence-specific DNA binding transcription factor activity |
ENSNLEP00000018707 | GO:0071392 | biological_process | cellular response to estradiol stimulus |
ENSNLEP00000018707 | GO:0005634 | cellular_component | nucleus |
ENSNLEP00000018707 | GO:0005794 | cellular_component | Golgi apparatus |
ENSNLEP00000018707 | GO:0005886 | cellular_component | plasma membrane |
ENSNLEP00000018707 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSNLEP00000018707 | GO:0003707 | molecular_function | steroid hormone receptor activity |
ENSNLEP00000018707 | GO:0005496 | molecular_function | steroid binding |
ENSNLEP00000018707 | GO:0008270 | molecular_function | zinc ion binding |
ENSNLEP00000018707 | GO:0030284 | molecular_function | estrogen receptor activity |
ENSNLEP00000018707 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
13616 | Monodelphis domestica | 100027187 | 9555 | Papio anubis | 100303417 |
9986 | Oryctolagus cuniculus | 100351261 | 9601 | Pongo abelii | 100459579 |
9483 | Callithrix jacchus | 100385918 | 9103 | Meleagris gallopavo | 100542782 |
10141 | Cavia porcellus | 100713276 | 10029 | Cricetulus griseus | 100768474 |
39432 | Saimiri boliviensis | 101034130 | 9669 | Mustela putorius furo | 101690352 |
8083 | Xiphophorus maculatus | 102235986 | 13735 | Pelodiscus sinensis | 102456765 |
9606 | Homo sapiens | 2099 | 9544 | Macaca mulatta | 574110 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000011072 | 7955 | Danio rerio | ENSDARG00000004111 |
9371 | Echinops telfairi | ENSETEG00000006131 | 9685 | Felis catus | ENSFCAG00000031492 |
69293 | Gasterosteus aculeatus | ENSGACG00000008711 | 9031 | Gallus gallus | ENSGALG00000012973 |
30608 | Microcebus murinus | ENSMICG00000007592 | 59463 | Myotis lucifugus | ENSMLUG00000014181 |
30611 | Otolemur garnettii | ENSOGAG00000012580 | 8090 | Oryzias latipes | ENSORLG00000014514 |
10116 | Rattus norvegicus | ENSRNOG00000019358 | 42254 | Sorex araneus | ENSSARG00000004419 |
31033 | Takifugu rubripes | ENSTRUG00000018219 | 9478 | Tarsius syrichta | ENSTSYG00000006280 |
9739 | Tursiops truncatus | ENSTTRG00000002996 | 8364 | Xenopus tropicalis | ENSXETG00000012364 |
9597 | Pan paniscus | 100980011 | 7897 | Latimeria chalumnae | 102366308 |
10090 | Mus musculus | 13982 | 9615 | Canis familiaris | 403640 |
9598 | Pan troglodytes | 452964 | 28377 | Anolis carolinensis | ENSACAG00000006213 |
9913 | Bos taurus | ENSBTAG00000007159 | 9358 | Choloepus hoffmanni | ENSCHOG00000012987 |
9361 | Dasypus novemcinctus | ENSDNOG00000013868 | 10020 | Dipodomys ordii | ENSDORG00000010443 |
9796 | Equus caballus | ENSECAG00000022441 | 9365 | Erinaceus europaeus | ENSEEUG00000000828 |
9595 | Gorilla gorilla | ENSGGOG00000009678 | 8049 | Gadus morhua | ENSGMOG00000014898 |
9785 | Loxodonta africana | ENSLAFG00000017799 | 9315 | Macropus eugenii | ENSMEUG00000003564 |
9258 | Ornithorhynchus anatinus | ENSOANG00000015561 | 8128 | Oreochromis niloticus | ENSONIG00000013354 |
9978 | Ochotona princeps | ENSOPRG00000012663 | 9813 | Procavia capensis | ENSPCAG00000011157 |
7757 | Petromyzon marinus | ENSPMAG00000008530 | 132908 | Pteropus vampyrus | ENSPVAG00000001923 |
9305 | Sarcophilus harrisii | ENSSHAG00000008174 | 9823 | Sus scrofa | ENSSSCG00000005109 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000006748 | 37347 | Tupaia belangeri | ENSTBEG00000005946 |
59729 | Taeniopygia guttata | ENSTGUG00000011249 | 99883 | Tetraodon nigroviridis | ENSTNIG00000012264 |
30538 | Vicugna pacos | ENSVPAG00000001185 |