Basic Information
Gene ID 100713276
Gene Name LOC100713276
Full Name Estrogen receptor
Organism Cavia porcellus [10141]

Cross Reference
UniProt H0VC28 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCPOP00000007475 Gene3D G3DSA:1.10.565.10 IPR008946 240 270 3.30e-97 Nuclear hormone receptor, ligand-binding
ENSCPOP00000007475 Gene3D G3DSA:1.10.565.10 IPR008946 312 549 3.30e-97 Nuclear hormone receptor, ligand-binding
ENSCPOP00000007475 Gene3D G3DSA:3.30.50.10 IPR013088 186 239 1.10e-27 Zinc finger, NHR/GATA-type
ENSCPOP00000007475 Pfam PF00104 IPR000536 330 525 9.00e-28 Nuclear hormone receptor, ligand-binding, core
ENSCPOP00000007475 Pfam PF00105 IPR001628 185 252 5.30e-31 Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 Pfam PF02159 IPR001292 48 182 8.50e-50 Oestrogen receptor
ENSCPOP00000007475 Pfam PF12743 IPR024736 554 596 2.70e-18 Oestrogen-type nuclear receptor final C-terminal domain
ENSCPOP00000007475 PIRSF PIRSF002527 IPR024178 42 591 1.50e-286 Oestrogen receptor/oestrogen-related receptor
ENSCPOP00000007475 PIRSF PIRSF500101 IPR001292 1 596 0.00e-00 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00047 IPR001628 186 202 1.30e-16 Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 PRINTS PR00047 IPR001628 202 217 1.30e-16 Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 PRINTS PR00047 IPR001628 235 243 1.30e-16 Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 PRINTS PR00047 IPR001628 243 251 1.30e-16 Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 PRINTS PR00398 IPR001723 247 257 3.40e-26 Steroid hormone receptor
ENSCPOP00000007475 PRINTS PR00398 IPR001723 350 371 3.40e-26 Steroid hormone receptor
ENSCPOP00000007475 PRINTS PR00398 IPR001723 371 387 3.40e-26 Steroid hormone receptor
ENSCPOP00000007475 PRINTS PR00398 IPR001723 439 454 3.40e-26 Steroid hormone receptor
ENSCPOP00000007475 PRINTS PR00398 IPR001723 507 524 3.40e-26 Steroid hormone receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 116 132 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 133 152 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 154 173 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 26 43 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 45 62 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 6 24 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 70 85 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 PRINTS PR00543 IPR001292 98 112 8.50e-77 Oestrogen receptor
ENSCPOP00000007475 ProSitePatterns PS00031 IPR001628 186 212 - Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 ProSiteProfiles PS51030 IPR001628 183 258 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 SMART SM00399 IPR001628 183 254 3.80e-39 Zinc finger, nuclear hormone receptor-type
ENSCPOP00000007475 SMART SM00430 IPR000536 349 519 1.30e-37 Nuclear hormone receptor, ligand-binding, core
ENSCPOP00000007475 SUPERFAMILY SSF48508 IPR008946 236 262 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSCPOP00000007475 SUPERFAMILY SSF48508 IPR008946 303 548 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCPOP00000007475 PF02159 0 Oest_recep Oestrogen receptor
ENSCPOP00000007475 PF00105 3.3e-31 zf-C4 Zinc finger, C4 type (two domains)
ENSCPOP00000007475 PF00104 5.7e-28 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSCPOP00000007475 PF12743 1.3e-18 ESR1_C Oestrogen-type nuclear receptor final C-terminal

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCPOP00000007475 GO:0006351 biological_process transcription, DNA-templated
ENSCPOP00000007475 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSCPOP00000007475 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
ENSCPOP00000007475 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
ENSCPOP00000007475 GO:0010863 biological_process positive regulation of phospholipase C activity
ENSCPOP00000007475 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
ENSCPOP00000007475 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
ENSCPOP00000007475 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
ENSCPOP00000007475 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
ENSCPOP00000007475 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
ENSCPOP00000007475 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSCPOP00000007475 GO:0071392 biological_process cellular response to estradiol stimulus
ENSCPOP00000007475 GO:0005634 cellular_component nucleus
ENSCPOP00000007475 GO:0005794 cellular_component Golgi apparatus
ENSCPOP00000007475 GO:0005886 cellular_component plasma membrane
ENSCPOP00000007475 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCPOP00000007475 GO:0003707 molecular_function steroid hormone receptor activity
ENSCPOP00000007475 GO:0005496 molecular_function steroid binding
ENSCPOP00000007475 GO:0008270 molecular_function zinc ion binding
ENSCPOP00000007475 GO:0030284 molecular_function estrogen receptor activity
ENSCPOP00000007475 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100027187 9555 Papio anubis 100303417
9986 Oryctolagus cuniculus 100351261 9103 Meleagris gallopavo 100542782
61853 Nomascus leucogenys 100580202 9483 Callithrix jacchus 100385918
9669 Mustela putorius furo 101690352 31033 Takifugu rubripes ENSTRUG00000018219
10029 Cricetulus griseus 100768474 9597 Pan paniscus 100980011
39432 Saimiri boliviensis 101034130 8083 Xiphophorus maculatus 102235986
13735 Pelodiscus sinensis 102456765 10090 Mus musculus 13982
9606 Homo sapiens 2099 9615 Canis familiaris 403640
28377 Anolis carolinensis ENSACAG00000006213 9646 Ailuropoda melanoleuca ENSAMEG00000011072
9913 Bos taurus ENSBTAG00000007159 7955 Danio rerio ENSDARG00000004111
10020 Dipodomys ordii ENSDORG00000010443 9796 Equus caballus ENSECAG00000022441
9365 Erinaceus europaeus ENSEEUG00000000828 9371 Echinops telfairi ENSETEG00000006131
9685 Felis catus ENSFCAG00000031492 69293 Gasterosteus aculeatus ENSGACG00000008711
9031 Gallus gallus ENSGALG00000012973 9595 Gorilla gorilla ENSGGOG00000009678
8049 Gadus morhua ENSGMOG00000014898 9315 Macropus eugenii ENSMEUG00000003564
30608 Microcebus murinus ENSMICG00000007592 59463 Myotis lucifugus ENSMLUG00000014181
9258 Ornithorhynchus anatinus ENSOANG00000015561 30611 Otolemur garnettii ENSOGAG00000012580
8128 Oreochromis niloticus ENSONIG00000013354 9978 Ochotona princeps ENSOPRG00000012663
8090 Oryzias latipes ENSORLG00000014514 132908 Pteropus vampyrus ENSPVAG00000001923
10116 Rattus norvegicus ENSRNOG00000019358 42254 Sorex araneus ENSSARG00000004419
43179 Ictidomys tridecemlineatus ENSSTOG00000006748 37347 Tupaia belangeri ENSTBEG00000005946
59729 Taeniopygia guttata ENSTGUG00000011249 99883 Tetraodon nigroviridis ENSTNIG00000012264
9478 Tarsius syrichta ENSTSYG00000006280 9739 Tursiops truncatus ENSTTRG00000002996
30538 Vicugna pacos ENSVPAG00000001185 8364 Xenopus tropicalis ENSXETG00000012364