Basic Information
Gene ID ENSRNOG00000019358 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Esr1
Full Name Estrogen receptor
Organism Rattus norvegicus [10116]

Cross Reference
UniProt F1M839 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000026350 Gene3D G3DSA:1.10.565.10 IPR008946 244 274 2.00e-34 Nuclear hormone receptor, ligand-binding
ENSRNOP00000026350 Gene3D G3DSA:1.10.565.10 IPR008946 316 370 2.00e-34 Nuclear hormone receptor, ligand-binding
ENSRNOP00000026350 Gene3D G3DSA:3.30.50.10 IPR013088 190 243 4.80e-28 Zinc finger, NHR/GATA-type
ENSRNOP00000026350 Pfam PF00105 IPR001628 189 257 1.10e-31 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 Pfam PF02159 IPR001292 42 186 6.20e-55 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00047 IPR001628 190 206 1.60e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 PRINTS PR00047 IPR001628 206 221 1.60e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 PRINTS PR00047 IPR001628 239 247 1.60e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 PRINTS PR00047 IPR001628 247 255 1.60e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 PRINTS PR00543 IPR001292 102 116 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00543 IPR001292 120 136 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00543 IPR001292 137 156 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00543 IPR001292 158 177 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00543 IPR001292 26 43 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00543 IPR001292 45 62 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00543 IPR001292 6 24 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 PRINTS PR00543 IPR001292 75 90 1.20e-83 Oestrogen receptor
ENSRNOP00000026350 ProSitePatterns PS00031 IPR001628 190 216 - Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 ProSiteProfiles PS51030 IPR001628 187 262 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 SMART SM00399 IPR001628 187 258 6.40e-40 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000026350 SUPERFAMILY SSF48508 IPR008946 239 266 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSRNOP00000026350 SUPERFAMILY SSF48508 IPR008946 307 370 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000026350 PF02159 0 Oest_recep Oestrogen receptor
ENSRNOP00000026350 PF00105 7.1e-32 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000026350 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000026350 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSRNOP00000026350 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
ENSRNOP00000026350 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
ENSRNOP00000026350 GO:0010863 biological_process positive regulation of phospholipase C activity
ENSRNOP00000026350 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
ENSRNOP00000026350 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
ENSRNOP00000026350 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
ENSRNOP00000026350 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
ENSRNOP00000026350 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
ENSRNOP00000026350 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSRNOP00000026350 GO:0071392 biological_process cellular response to estradiol stimulus
ENSRNOP00000026350 GO:0005634 cellular_component nucleus
ENSRNOP00000026350 GO:0005794 cellular_component Golgi apparatus
ENSRNOP00000026350 GO:0005886 cellular_component plasma membrane
ENSRNOP00000026350 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSRNOP00000026350 GO:0003707 molecular_function steroid hormone receptor activity
ENSRNOP00000026350 GO:0005496 molecular_function steroid binding
ENSRNOP00000026350 GO:0008270 molecular_function zinc ion binding
ENSRNOP00000026350 GO:0030284 molecular_function estrogen receptor activity
ENSRNOP00000026350 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100027187 9555 Papio anubis 100303417
9986 Oryctolagus cuniculus 100351261 61853 Nomascus leucogenys 100580202
9597 Pan paniscus 100980011 10090 Mus musculus 13982
9615 Canis familiaris 403640 28377 Anolis carolinensis ENSACAG00000006213
9913 Bos taurus ENSBTAG00000007159 9796 Equus caballus ENSECAG00000022441
9365 Erinaceus europaeus ENSEEUG00000000828 9595 Gorilla gorilla ENSGGOG00000009678
9315 Macropus eugenii ENSMEUG00000003564 9258 Ornithorhynchus anatinus ENSOANG00000003331
9978 Ochotona princeps ENSOPRG00000012663 9813 Procavia capensis ENSPCAG00000015346
132908 Pteropus vampyrus ENSPVAG00000001923 9483 Callithrix jacchus 100385918
9103 Meleagris gallopavo 100542782 10141 Cavia porcellus 100713276
10029 Cricetulus griseus 100768474 39432 Saimiri boliviensis 101040869
9669 Mustela putorius furo 101690352 13735 Pelodiscus sinensis 102456765
9606 Homo sapiens 2099 9371 Echinops telfairi ENSETEG00000006131
9031 Gallus gallus ENSGALG00000012973 30608 Microcebus murinus ENSMICG00000007592
59463 Myotis lucifugus ENSMLUG00000014181 30611 Otolemur garnettii ENSOGAG00000012580
42254 Sorex araneus ENSSARG00000004419 9478 Tarsius syrichta ENSTSYG00000006280
9739 Tursiops truncatus ENSTTRG00000002996 8364 Xenopus tropicalis ENSXETG00000012364
43179 Ictidomys tridecemlineatus ENSSTOG00000006748 37347 Tupaia belangeri ENSTBEG00000005946
59729 Taeniopygia guttata ENSTGUG00000011249 30538 Vicugna pacos ENSVPAG00000001185