Basic Information
Gene ID 100051258
Gene Name PPARG
Full Name Uncharacterized protein
Organism Equus caballus [9796]

Cross Reference
UniProt F6Z3I2 UniGene NULL
PDB NULL OMIM NULL
KEGG ecb:100051258 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSECAP00000014533 Gene3D G3DSA:1.10.565.10 IPR008946 161 191 7.00e-76 Nuclear hormone receptor, ligand-binding
ENSECAP00000014533 Gene3D G3DSA:1.10.565.10 IPR008946 247 471 7.00e-76 Nuclear hormone receptor, ligand-binding
ENSECAP00000014533 Gene3D G3DSA:3.30.50.10 IPR013088 108 160 2.00e-24 Zinc finger, NHR/GATA-type
ENSECAP00000014533 Pfam PF00104 IPR000536 290 453 1.00e-30 Nuclear hormone receptor, ligand-binding, core
ENSECAP00000014533 Pfam PF00105 IPR001628 107 173 2.40e-27 Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 Pfam PF12577 IPR022590 1 77 1.60e-31 Peroxisome proliferator-activated receptor gamma, N-terminal
ENSECAP00000014533 PRINTS PR00047 IPR001628 108 124 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 PRINTS PR00047 IPR001628 124 139 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 PRINTS PR00047 IPR001628 156 164 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 PRINTS PR00047 IPR001628 164 172 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 PRINTS PR00398 IPR001723 168 178 7.10e-28 Steroid hormone receptor
ENSECAP00000014533 PRINTS PR00398 IPR001723 285 306 7.10e-28 Steroid hormone receptor
ENSECAP00000014533 PRINTS PR00398 IPR001723 306 322 7.10e-28 Steroid hormone receptor
ENSECAP00000014533 PRINTS PR00398 IPR001723 374 389 7.10e-28 Steroid hormone receptor
ENSECAP00000014533 PRINTS PR00398 IPR001723 431 448 7.10e-28 Steroid hormone receptor
ENSECAP00000014533 PRINTS PR01288 IPR003074 197 211 2.80e-64 Peroxisome proliferator-activated receptor
ENSECAP00000014533 PRINTS PR01288 IPR003074 211 230 2.80e-64 Peroxisome proliferator-activated receptor
ENSECAP00000014533 PRINTS PR01288 IPR003074 324 337 2.80e-64 Peroxisome proliferator-activated receptor
ENSECAP00000014533 PRINTS PR01288 IPR003074 341 356 2.80e-64 Peroxisome proliferator-activated receptor
ENSECAP00000014533 PRINTS PR01288 IPR003074 359 372 2.80e-64 Peroxisome proliferator-activated receptor
ENSECAP00000014533 PRINTS PR01288 IPR003074 421 438 2.80e-64 Peroxisome proliferator-activated receptor
ENSECAP00000014533 PRINTS PR01288 IPR003074 455 467 2.80e-64 Peroxisome proliferator-activated receptor
ENSECAP00000014533 PRINTS PR01291 IPR003077 12 26 9.40e-50 Peroxisome proliferator-activated receptor, gamma
ENSECAP00000014533 PRINTS PR01291 IPR003077 184 200 9.40e-50 Peroxisome proliferator-activated receptor, gamma
ENSECAP00000014533 PRINTS PR01291 IPR003077 30 43 9.40e-50 Peroxisome proliferator-activated receptor, gamma
ENSECAP00000014533 PRINTS PR01291 IPR003077 408 421 9.40e-50 Peroxisome proliferator-activated receptor, gamma
ENSECAP00000014533 PRINTS PR01291 IPR003077 54 71 9.40e-50 Peroxisome proliferator-activated receptor, gamma
ENSECAP00000014533 PRINTS PR01291 IPR003077 72 90 9.40e-50 Peroxisome proliferator-activated receptor, gamma
ENSECAP00000014533 ProSitePatterns PS00031 IPR001628 108 134 - Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 ProSiteProfiles PS51030 IPR001628 105 179 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 SMART SM00399 IPR001628 105 175 8.50e-37 Zinc finger, nuclear hormone receptor-type
ENSECAP00000014533 SMART SM00430 IPR000536 284 443 7.40e-30 Nuclear hormone receptor, ligand-binding, core
ENSECAP00000014533 SUPERFAMILY SSF48508 IPR008946 209 472 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSECAP00000014533 PF12577 4.1e-32 PPARgamma_N PPAR gamma N-terminal region
ENSECAP00000014533 PF00104 4.6e-31 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSECAP00000014533 PF00105 1.5e-27 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSECAP00000014533 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSECAP00000014533 GO:0001890 biological_process placenta development
ENSECAP00000014533 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSECAP00000014533 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
ENSECAP00000014533 GO:0008217 biological_process regulation of blood pressure
ENSECAP00000014533 GO:0010871 biological_process negative regulation of receptor biosynthetic process
ENSECAP00000014533 GO:0010887 biological_process negative regulation of cholesterol storage
ENSECAP00000014533 GO:0010891 biological_process negative regulation of sequestering of triglyceride
ENSECAP00000014533 GO:0015909 biological_process long-chain fatty acid transport
ENSECAP00000014533 GO:0030224 biological_process monocyte differentiation
ENSECAP00000014533 GO:0030855 biological_process epithelial cell differentiation
ENSECAP00000014533 GO:0032526 biological_process response to retinoic acid
ENSECAP00000014533 GO:0032869 biological_process cellular response to insulin stimulus
ENSECAP00000014533 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
ENSECAP00000014533 GO:0042593 biological_process glucose homeostasis
ENSECAP00000014533 GO:0042953 biological_process lipoprotein transport
ENSECAP00000014533 GO:0045165 biological_process cell fate commitment
ENSECAP00000014533 GO:0045600 biological_process positive regulation of fat cell differentiation
ENSECAP00000014533 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
ENSECAP00000014533 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSECAP00000014533 GO:0048469 biological_process cell maturation
ENSECAP00000014533 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
ENSECAP00000014533 GO:0050872 biological_process white fat cell differentiation
ENSECAP00000014533 GO:0050873 biological_process brown fat cell differentiation
ENSECAP00000014533 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSECAP00000014533 GO:0055098 biological_process response to low-density lipoprotein particle
ENSECAP00000014533 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
ENSECAP00000014533 GO:0071285 biological_process cellular response to lithium ion
ENSECAP00000014533 GO:0005634 cellular_component nucleus
ENSECAP00000014533 GO:0005829 cellular_component cytosol
ENSECAP00000014533 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
ENSECAP00000014533 GO:0003677 molecular_function DNA binding
ENSECAP00000014533 GO:0003682 molecular_function chromatin binding
ENSECAP00000014533 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSECAP00000014533 GO:0003707 molecular_function steroid hormone receptor activity
ENSECAP00000014533 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSECAP00000014533 GO:0008144 molecular_function drug binding
ENSECAP00000014533 GO:0008270 molecular_function zinc ion binding
ENSECAP00000014533 GO:0019899 molecular_function enzyme binding
ENSECAP00000014533 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSECAP00000014533 GO:0033613 molecular_function activating transcription factor binding
ENSECAP00000014533 GO:0043565 molecular_function sequence-specific DNA binding
ENSECAP00000014533 GO:0046965 molecular_function retinoid X receptor binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys 100581046 30195 Bombus terrestris 100644185
10029 Cricetulus griseus 100689245 8128 Oreochromis niloticus 100711231
132113 Bombus impatiens 100744917 143995 Megachile rotundata 100876784
9597 Pan paniscus 100974825 9685 Felis catus 101095161
9595 Gorilla gorilla 101134077 59463 Myotis lucifugus 102435787
7227 Drosophila melanogaster 39999 9646 Ailuropoda melanoleuca ENSAMEG00000004774
9358 Choloepus hoffmanni ENSCHOG00000007152 9361 Dasypus novemcinctus ENSDNOG00000018641
9371 Echinops telfairi ENSETEG00000001775 69293 Gasterosteus aculeatus ENSGACG00000001665
8049 Gadus morhua ENSGMOG00000001375 7897 Latimeria chalumnae ENSLACG00000009212
9315 Macropus eugenii ENSMEUG00000007824 9978 Ochotona princeps ENSOPRG00000003439
8090 Oryzias latipes ENSORLG00000004432 9813 Procavia capensis ENSPCAG00000001034
9601 Pongo abelii ENSPPYG00000013648 13735 Pelodiscus sinensis ENSPSIG00000011100
42254 Sorex araneus ENSSARG00000009808 43179 Ictidomys tridecemlineatus ENSSTOG00000012778
59729 Taeniopygia guttata ENSTGUG00000004069 9478 Tarsius syrichta ENSTSYG00000006950
9739 Tursiops truncatus ENSTTRG00000016565 8083 Xiphophorus maculatus ENSXMAG00000017330
34638 Metaseiulus occidentalis 100899165 9305 Sarcophilus harrisii 100934154
30611 Otolemur garnettii 100943160 39432 Saimiri boliviensis 101028278
9669 Mustela putorius furo 101688974 10090 Mus musculus 19016
10116 Rattus norvegicus 25664 9031 Gallus gallus 373928
9823 Sus scrofa 397671 7460 Apis mellifera 410309
7668 Strongylocentrotus purpuratus 580686 7070 Tribolium castaneum 660005
28377 Anolis carolinensis ENSACAG00000013360 9615 Canis familiaris ENSCAFG00000004991
7955 Danio rerio ENSDARG00000031848 9365 Erinaceus europaeus ENSEEUG00000006334
9785 Loxodonta africana ENSLAFG00000030870 30608 Microcebus murinus ENSMICG00000016663
9544 Macaca mulatta ENSMMUG00000007191 132908 Pteropus vampyrus ENSPVAG00000009845
37347 Tupaia belangeri ENSTBEG00000011278 99883 Tetraodon nigroviridis ENSTNIG00000014805
31033 Takifugu rubripes ENSTRUG00000015522 30538 Vicugna pacos ENSVPAG00000011059
8364 Xenopus tropicalis ENSXETG00000017422