Basic Information
Gene ID 100689245
Gene Name PPARG; NR1C3
Full Name Peroxisome proliferator-activated receptor gamma
Organism Cricetulus griseus [10029]

Cross Reference
UniProt P57797 UniGene NULL
PDB NULL OMIM NULL
KEGG cge:100689245 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_001231210 Gene3D G3DSA:1.10.565.10 IPR008946 162 192 4.30e-74 Nuclear hormone receptor, ligand-binding
NP_001231210 Gene3D G3DSA:1.10.565.10 IPR008946 248 472 4.30e-74 Nuclear hormone receptor, ligand-binding
NP_001231210 Gene3D G3DSA:3.30.50.10 IPR013088 109 161 2.10e-24 Zinc finger, NHR/GATA-type
NP_001231210 Pfam PF00104 IPR000536 291 454 1.40e-29 Nuclear hormone receptor, ligand-binding, core
NP_001231210 Pfam PF00105 IPR001628 108 174 2.40e-27 Zinc finger, nuclear hormone receptor-type
NP_001231210 Pfam PF12577 IPR022590 1 78 6.50e-33 Peroxisome proliferator-activated receptor gamma, N-terminal
NP_001231210 PRINTS PR00047 IPR001628 109 125 4.80e-19 Zinc finger, nuclear hormone receptor-type
NP_001231210 PRINTS PR00047 IPR001628 125 140 4.80e-19 Zinc finger, nuclear hormone receptor-type
NP_001231210 PRINTS PR00047 IPR001628 157 165 4.80e-19 Zinc finger, nuclear hormone receptor-type
NP_001231210 PRINTS PR00047 IPR001628 165 173 4.80e-19 Zinc finger, nuclear hormone receptor-type
NP_001231210 PRINTS PR00398 IPR001723 169 179 3.90e-27 Steroid hormone receptor
NP_001231210 PRINTS PR00398 IPR001723 286 307 3.90e-27 Steroid hormone receptor
NP_001231210 PRINTS PR00398 IPR001723 307 323 3.90e-27 Steroid hormone receptor
NP_001231210 PRINTS PR00398 IPR001723 375 390 3.90e-27 Steroid hormone receptor
NP_001231210 PRINTS PR00398 IPR001723 432 449 3.90e-27 Steroid hormone receptor
NP_001231210 PRINTS PR01288 IPR003074 198 212 6.50e-64 Peroxisome proliferator-activated receptor
NP_001231210 PRINTS PR01288 IPR003074 212 231 6.50e-64 Peroxisome proliferator-activated receptor
NP_001231210 PRINTS PR01288 IPR003074 325 338 6.50e-64 Peroxisome proliferator-activated receptor
NP_001231210 PRINTS PR01288 IPR003074 342 357 6.50e-64 Peroxisome proliferator-activated receptor
NP_001231210 PRINTS PR01288 IPR003074 360 373 6.50e-64 Peroxisome proliferator-activated receptor
NP_001231210 PRINTS PR01288 IPR003074 422 439 6.50e-64 Peroxisome proliferator-activated receptor
NP_001231210 PRINTS PR01288 IPR003074 456 468 6.50e-64 Peroxisome proliferator-activated receptor
NP_001231210 PRINTS PR01291 IPR003077 12 26 5.40e-54 Peroxisome proliferator-activated receptor, gamma
NP_001231210 PRINTS PR01291 IPR003077 185 201 5.40e-54 Peroxisome proliferator-activated receptor, gamma
NP_001231210 PRINTS PR01291 IPR003077 30 43 5.40e-54 Peroxisome proliferator-activated receptor, gamma
NP_001231210 PRINTS PR01291 IPR003077 409 422 5.40e-54 Peroxisome proliferator-activated receptor, gamma
NP_001231210 PRINTS PR01291 IPR003077 55 72 5.40e-54 Peroxisome proliferator-activated receptor, gamma
NP_001231210 PRINTS PR01291 IPR003077 73 91 5.40e-54 Peroxisome proliferator-activated receptor, gamma
NP_001231210 ProSitePatterns PS00031 IPR001628 109 135 - Zinc finger, nuclear hormone receptor-type
NP_001231210 ProSiteProfiles PS51030 IPR001628 106 180 0.00e-00 Zinc finger, nuclear hormone receptor-type
NP_001231210 SMART SM00399 IPR001628 106 176 8.50e-37 Zinc finger, nuclear hormone receptor-type
NP_001231210 SMART SM00430 IPR000536 285 444 3.20e-28 Nuclear hormone receptor, ligand-binding, core
NP_001231210 SUPERFAMILY SSF48508 IPR008946 210 473 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_001231210 PF12577 2.4e-33 PPARgamma_N PPAR gamma N-terminal region
NP_001231210 PF00104 6.7e-30 Hormone_recep Ligand-binding domain of nuclear hormone receptor
NP_001231210 PF00105 1.5e-27 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
NP_001231210 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
NP_001231210 GO:0001890 biological_process placenta development
NP_001231210 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_001231210 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
NP_001231210 GO:0008217 biological_process regulation of blood pressure
NP_001231210 GO:0010871 biological_process negative regulation of receptor biosynthetic process
NP_001231210 GO:0010887 biological_process negative regulation of cholesterol storage
NP_001231210 GO:0010891 biological_process negative regulation of sequestering of triglyceride
NP_001231210 GO:0015909 biological_process long-chain fatty acid transport
NP_001231210 GO:0030224 biological_process monocyte differentiation
NP_001231210 GO:0030855 biological_process epithelial cell differentiation
NP_001231210 GO:0032526 biological_process response to retinoic acid
NP_001231210 GO:0032869 biological_process cellular response to insulin stimulus
NP_001231210 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
NP_001231210 GO:0042593 biological_process glucose homeostasis
NP_001231210 GO:0042953 biological_process lipoprotein transport
NP_001231210 GO:0045165 biological_process cell fate commitment
NP_001231210 GO:0045600 biological_process positive regulation of fat cell differentiation
NP_001231210 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
NP_001231210 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
NP_001231210 GO:0048469 biological_process cell maturation
NP_001231210 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
NP_001231210 GO:0050872 biological_process white fat cell differentiation
NP_001231210 GO:0050873 biological_process brown fat cell differentiation
NP_001231210 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
NP_001231210 GO:0055098 biological_process response to low-density lipoprotein particle
NP_001231210 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
NP_001231210 GO:0071285 biological_process cellular response to lithium ion
NP_001231210 GO:0005634 cellular_component nucleus
NP_001231210 GO:0005829 cellular_component cytosol
NP_001231210 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
NP_001231210 GO:0003677 molecular_function DNA binding
NP_001231210 GO:0003682 molecular_function chromatin binding
NP_001231210 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_001231210 GO:0003707 molecular_function steroid hormone receptor activity
NP_001231210 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
NP_001231210 GO:0008144 molecular_function drug binding
NP_001231210 GO:0008270 molecular_function zinc ion binding
NP_001231210 GO:0019899 molecular_function enzyme binding
NP_001231210 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
NP_001231210 GO:0033613 molecular_function activating transcription factor binding
NP_001231210 GO:0043565 molecular_function sequence-specific DNA binding
NP_001231210 GO:0046965 molecular_function retinoid X receptor binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100051258 61853 Nomascus leucogenys 100581046
8128 Oreochromis niloticus 100711231 132113 Bombus impatiens 100744917
143995 Megachile rotundata 100876784 9555 Papio anubis 101012073
9685 Felis catus 101095161 9595 Gorilla gorilla 101134077
9646 Ailuropoda melanoleuca ENSAMEG00000004774 9358 Choloepus hoffmanni ENSCHOG00000007152
9361 Dasypus novemcinctus ENSDNOG00000018641 9371 Echinops telfairi ENSETEG00000001775
7897 Latimeria chalumnae ENSLACG00000009212 9315 Macropus eugenii ENSMEUG00000007824
8090 Oryzias latipes ENSORLG00000004432 9813 Procavia capensis ENSPCAG00000001034
9601 Pongo abelii ENSPPYG00000013648 13735 Pelodiscus sinensis ENSPSIG00000011100
59729 Taeniopygia guttata ENSTGUG00000004069 8083 Xiphophorus maculatus ENSXMAG00000017330
34638 Metaseiulus occidentalis 100899165 9305 Sarcophilus harrisii 100934154
30611 Otolemur garnettii 100943160 9597 Pan paniscus 100974825
39432 Saimiri boliviensis 101028278 9669 Mustela putorius furo 101688974
59463 Myotis lucifugus 102435787 10090 Mus musculus 19016
10116 Rattus norvegicus 25664 9031 Gallus gallus 373928
9823 Sus scrofa 397671 7227 Drosophila melanogaster 39999
7460 Apis mellifera 410309 7070 Tribolium castaneum 660005
28377 Anolis carolinensis ENSACAG00000013360 9615 Canis familiaris ENSCAFG00000004991
7955 Danio rerio ENSDARG00000031848 9365 Erinaceus europaeus ENSEEUG00000006334
69293 Gasterosteus aculeatus ENSGACG00000001665 8049 Gadus morhua ENSGMOG00000001375
9785 Loxodonta africana ENSLAFG00000030870 30608 Microcebus murinus ENSMICG00000016663
9544 Macaca mulatta ENSMMUG00000007191 9978 Ochotona princeps ENSOPRG00000003439
132908 Pteropus vampyrus ENSPVAG00000009845 42254 Sorex araneus ENSSARG00000009808
43179 Ictidomys tridecemlineatus ENSSTOG00000012778 37347 Tupaia belangeri ENSTBEG00000011278
99883 Tetraodon nigroviridis ENSTNIG00000014805 31033 Takifugu rubripes ENSTRUG00000015522
9478 Tarsius syrichta ENSTSYG00000006950 9739 Tursiops truncatus ENSTTRG00000016565
30538 Vicugna pacos ENSVPAG00000011059 8364 Xenopus tropicalis ENSXETG00000017422