Basic Information
Gene ID ENSMMUG00000007191
Gene Name PPARG
Full Name Peroxisome proliferator-activated receptor gamma
Organism Macaca mulatta [9544]

Cross Reference
UniProt G1K373 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMMUP00000009427 Gene3D G3DSA:1.10.565.10 IPR008946 192 222 1.10e-49 Nuclear hormone receptor, ligand-binding
ENSMMUP00000009427 Gene3D G3DSA:1.10.565.10 IPR008946 278 422 1.10e-49 Nuclear hormone receptor, ligand-binding
ENSMMUP00000009427 Gene3D G3DSA:3.30.50.10 IPR013088 139 191 1.70e-24 Zinc finger, NHR/GATA-type
ENSMMUP00000009427 Pfam PF00104 IPR000536 321 422 7.60e-18 Nuclear hormone receptor, ligand-binding, core
ENSMMUP00000009427 Pfam PF00105 IPR001628 138 204 2.00e-27 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 Pfam PF12577 IPR022590 31 108 4.80e-33 Peroxisome proliferator-activated receptor gamma, N-terminal
ENSMMUP00000009427 PRINTS PR00047 IPR001628 139 155 3.20e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 PRINTS PR00047 IPR001628 155 170 3.20e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 PRINTS PR00047 IPR001628 187 195 3.20e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 PRINTS PR00047 IPR001628 195 203 3.20e-19 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 PRINTS PR00398 IPR001723 199 209 2.80e-20 Steroid hormone receptor
ENSMMUP00000009427 PRINTS PR00398 IPR001723 316 337 2.80e-20 Steroid hormone receptor
ENSMMUP00000009427 PRINTS PR00398 IPR001723 337 353 2.80e-20 Steroid hormone receptor
ENSMMUP00000009427 PRINTS PR00398 IPR001723 405 420 2.80e-20 Steroid hormone receptor
ENSMMUP00000009427 PRINTS PR01288 IPR003074 228 242 5.90e-46 Peroxisome proliferator-activated receptor
ENSMMUP00000009427 PRINTS PR01288 IPR003074 242 261 5.90e-46 Peroxisome proliferator-activated receptor
ENSMMUP00000009427 PRINTS PR01288 IPR003074 355 368 5.90e-46 Peroxisome proliferator-activated receptor
ENSMMUP00000009427 PRINTS PR01288 IPR003074 372 387 5.90e-46 Peroxisome proliferator-activated receptor
ENSMMUP00000009427 PRINTS PR01288 IPR003074 390 403 5.90e-46 Peroxisome proliferator-activated receptor
ENSMMUP00000009427 PRINTS PR01291 IPR003077 103 121 1.60e-46 Peroxisome proliferator-activated receptor, gamma
ENSMMUP00000009427 PRINTS PR01291 IPR003077 215 231 1.60e-46 Peroxisome proliferator-activated receptor, gamma
ENSMMUP00000009427 PRINTS PR01291 IPR003077 42 56 1.60e-46 Peroxisome proliferator-activated receptor, gamma
ENSMMUP00000009427 PRINTS PR01291 IPR003077 60 73 1.60e-46 Peroxisome proliferator-activated receptor, gamma
ENSMMUP00000009427 PRINTS PR01291 IPR003077 85 102 1.60e-46 Peroxisome proliferator-activated receptor, gamma
ENSMMUP00000009427 ProSitePatterns PS00031 IPR001628 139 165 - Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 ProSiteProfiles PS51030 IPR001628 136 210 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 SMART SM00399 IPR001628 136 206 8.50e-37 Zinc finger, nuclear hormone receptor-type
ENSMMUP00000009427 SUPERFAMILY SSF48508 IPR008946 240 422 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMMUP00000009427 PF12577 1.2e-33 PPARgamma_N PPAR gamma N-terminal region
ENSMMUP00000009427 PF00105 1.3e-27 zf-C4 Zinc finger, C4 type (two domains)
ENSMMUP00000009427 PF00104 3.4e-18 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMMUP00000009427 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSMMUP00000009427 GO:0001890 biological_process placenta development
ENSMMUP00000009427 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMMUP00000009427 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
ENSMMUP00000009427 GO:0008217 biological_process regulation of blood pressure
ENSMMUP00000009427 GO:0010871 biological_process negative regulation of receptor biosynthetic process
ENSMMUP00000009427 GO:0010887 biological_process negative regulation of cholesterol storage
ENSMMUP00000009427 GO:0010891 biological_process negative regulation of sequestering of triglyceride
ENSMMUP00000009427 GO:0015909 biological_process long-chain fatty acid transport
ENSMMUP00000009427 GO:0030224 biological_process monocyte differentiation
ENSMMUP00000009427 GO:0030855 biological_process epithelial cell differentiation
ENSMMUP00000009427 GO:0032526 biological_process response to retinoic acid
ENSMMUP00000009427 GO:0032869 biological_process cellular response to insulin stimulus
ENSMMUP00000009427 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
ENSMMUP00000009427 GO:0042593 biological_process glucose homeostasis
ENSMMUP00000009427 GO:0042953 biological_process lipoprotein transport
ENSMMUP00000009427 GO:0045165 biological_process cell fate commitment
ENSMMUP00000009427 GO:0045600 biological_process positive regulation of fat cell differentiation
ENSMMUP00000009427 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
ENSMMUP00000009427 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMMUP00000009427 GO:0048469 biological_process cell maturation
ENSMMUP00000009427 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
ENSMMUP00000009427 GO:0050872 biological_process white fat cell differentiation
ENSMMUP00000009427 GO:0050873 biological_process brown fat cell differentiation
ENSMMUP00000009427 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSMMUP00000009427 GO:0055098 biological_process response to low-density lipoprotein particle
ENSMMUP00000009427 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
ENSMMUP00000009427 GO:0071285 biological_process cellular response to lithium ion
ENSMMUP00000009427 GO:0005634 cellular_component nucleus
ENSMMUP00000009427 GO:0005829 cellular_component cytosol
ENSMMUP00000009427 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
ENSMMUP00000009427 GO:0003677 molecular_function DNA binding
ENSMMUP00000009427 GO:0003682 molecular_function chromatin binding
ENSMMUP00000009427 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMMUP00000009427 GO:0003707 molecular_function steroid hormone receptor activity
ENSMMUP00000009427 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSMMUP00000009427 GO:0008144 molecular_function drug binding
ENSMMUP00000009427 GO:0008270 molecular_function zinc ion binding
ENSMMUP00000009427 GO:0019899 molecular_function enzyme binding
ENSMMUP00000009427 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSMMUP00000009427 GO:0033613 molecular_function activating transcription factor binding
ENSMMUP00000009427 GO:0043565 molecular_function sequence-specific DNA binding
ENSMMUP00000009427 GO:0046965 molecular_function retinoid X receptor binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100329099 9305 Sarcophilus harrisii 100934154
30611 Otolemur garnettii 100943160 9669 Mustela putorius furo 101688974
10116 Rattus norvegicus 25664 9031 Gallus gallus 373928
28377 Anolis carolinensis ENSACAG00000013360 9615 Canis familiaris ENSCAFG00000004991
7955 Danio rerio ENSDARG00000031848 9365 Erinaceus europaeus ENSEEUG00000006334
9785 Loxodonta africana ENSLAFG00000030870 9796 Equus caballus 100051258
61853 Nomascus leucogenys 100581046 10029 Cricetulus griseus 100689245
8128 Oreochromis niloticus 100711231 9597 Pan paniscus 100974825
9555 Papio anubis 101012073 39432 Saimiri boliviensis 101028278
9685 Felis catus 101095161 9595 Gorilla gorilla 101134077
59463 Myotis lucifugus 102435787 10090 Mus musculus 19016
9823 Sus scrofa 397671 9646 Ailuropoda melanoleuca ENSAMEG00000004774
9358 Choloepus hoffmanni ENSCHOG00000007152 9361 Dasypus novemcinctus ENSDNOG00000018641
9371 Echinops telfairi ENSETEG00000001775 69293 Gasterosteus aculeatus ENSGACG00000001665
8049 Gadus morhua ENSGMOG00000001375 7897 Latimeria chalumnae ENSLACG00000009212
9315 Macropus eugenii ENSMEUG00000007824 30608 Microcebus murinus ENSMICG00000016663
9978 Ochotona princeps ENSOPRG00000003439 9813 Procavia capensis ENSPCAG00000001034
9601 Pongo abelii ENSPPYG00000013648 13735 Pelodiscus sinensis ENSPSIG00000011100
42254 Sorex araneus ENSSARG00000009808 43179 Ictidomys tridecemlineatus ENSSTOG00000012778
59729 Taeniopygia guttata ENSTGUG00000004069 31033 Takifugu rubripes ENSTRUG00000015522
9478 Tarsius syrichta ENSTSYG00000006950 9739 Tursiops truncatus ENSTTRG00000016565
8364 Xenopus tropicalis ENSXETG00000017422 132908 Pteropus vampyrus ENSPVAG00000009845
37347 Tupaia belangeri ENSTBEG00000011278 99883 Tetraodon nigroviridis ENSTNIG00000014805
30538 Vicugna pacos ENSVPAG00000011059