Basic Information
Gene ID ENSCAFG00000004991
Gene Name ENSCAFG00000004991
Full Name ENSCAFG00000004991
Organism Canis familiaris [9615]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCAFP00000007423 Gene3D G3DSA:1.10.565.10 IPR008946 216 246 9.70e-76 Nuclear hormone receptor, ligand-binding
ENSCAFP00000007423 Gene3D G3DSA:1.10.565.10 IPR008946 302 526 9.70e-76 Nuclear hormone receptor, ligand-binding
ENSCAFP00000007423 Gene3D G3DSA:3.30.50.10 IPR013088 163 215 2.40e-24 Zinc finger, NHR/GATA-type
ENSCAFP00000007423 Pfam PF00104 IPR000536 345 508 1.30e-30 Nuclear hormone receptor, ligand-binding, core
ENSCAFP00000007423 Pfam PF00105 IPR001628 162 228 2.80e-27 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 Pfam PF12577 IPR022590 55 132 9.70e-33 Peroxisome proliferator-activated receptor gamma, N-terminal
ENSCAFP00000007423 PRINTS PR00047 IPR001628 163 179 7.10e-19 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 PRINTS PR00047 IPR001628 179 194 7.10e-19 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 PRINTS PR00047 IPR001628 211 219 7.10e-19 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 PRINTS PR00047 IPR001628 219 227 7.10e-19 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 PRINTS PR00398 IPR001723 223 233 1.10e-27 Steroid hormone receptor
ENSCAFP00000007423 PRINTS PR00398 IPR001723 340 361 1.10e-27 Steroid hormone receptor
ENSCAFP00000007423 PRINTS PR00398 IPR001723 361 377 1.10e-27 Steroid hormone receptor
ENSCAFP00000007423 PRINTS PR00398 IPR001723 429 444 1.10e-27 Steroid hormone receptor
ENSCAFP00000007423 PRINTS PR00398 IPR001723 486 503 1.10e-27 Steroid hormone receptor
ENSCAFP00000007423 PRINTS PR01288 IPR003074 252 266 5.40e-64 Peroxisome proliferator-activated receptor
ENSCAFP00000007423 PRINTS PR01288 IPR003074 266 285 5.40e-64 Peroxisome proliferator-activated receptor
ENSCAFP00000007423 PRINTS PR01288 IPR003074 379 392 5.40e-64 Peroxisome proliferator-activated receptor
ENSCAFP00000007423 PRINTS PR01288 IPR003074 396 411 5.40e-64 Peroxisome proliferator-activated receptor
ENSCAFP00000007423 PRINTS PR01288 IPR003074 414 427 5.40e-64 Peroxisome proliferator-activated receptor
ENSCAFP00000007423 PRINTS PR01288 IPR003074 476 493 5.40e-64 Peroxisome proliferator-activated receptor
ENSCAFP00000007423 PRINTS PR01288 IPR003074 510 522 5.40e-64 Peroxisome proliferator-activated receptor
ENSCAFP00000007423 PRINTS PR01291 IPR003077 109 126 1.00e-54 Peroxisome proliferator-activated receptor, gamma
ENSCAFP00000007423 PRINTS PR01291 IPR003077 127 145 1.00e-54 Peroxisome proliferator-activated receptor, gamma
ENSCAFP00000007423 PRINTS PR01291 IPR003077 239 255 1.00e-54 Peroxisome proliferator-activated receptor, gamma
ENSCAFP00000007423 PRINTS PR01291 IPR003077 463 476 1.00e-54 Peroxisome proliferator-activated receptor, gamma
ENSCAFP00000007423 PRINTS PR01291 IPR003077 66 80 1.00e-54 Peroxisome proliferator-activated receptor, gamma
ENSCAFP00000007423 PRINTS PR01291 IPR003077 84 97 1.00e-54 Peroxisome proliferator-activated receptor, gamma
ENSCAFP00000007423 ProSitePatterns PS00031 IPR001628 163 189 - Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 ProSiteProfiles PS51030 IPR001628 160 234 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 SMART SM00399 IPR001628 160 230 8.50e-37 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000007423 SMART SM00430 IPR000536 339 498 7.40e-30 Nuclear hormone receptor, ligand-binding, core
ENSCAFP00000007423 SUPERFAMILY SSF48508 IPR008946 264 527 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCAFP00000007423 PF12577 3.6e-33 PPARgamma_N PPAR gamma N-terminal region
ENSCAFP00000007423 PF00104 5.8e-31 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSCAFP00000007423 PF00105 1.7e-27 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCAFP00000007423 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSCAFP00000007423 GO:0001890 biological_process placenta development
ENSCAFP00000007423 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSCAFP00000007423 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
ENSCAFP00000007423 GO:0008217 biological_process regulation of blood pressure
ENSCAFP00000007423 GO:0010871 biological_process negative regulation of receptor biosynthetic process
ENSCAFP00000007423 GO:0010887 biological_process negative regulation of cholesterol storage
ENSCAFP00000007423 GO:0010891 biological_process negative regulation of sequestering of triglyceride
ENSCAFP00000007423 GO:0015909 biological_process long-chain fatty acid transport
ENSCAFP00000007423 GO:0030224 biological_process monocyte differentiation
ENSCAFP00000007423 GO:0030855 biological_process epithelial cell differentiation
ENSCAFP00000007423 GO:0032526 biological_process response to retinoic acid
ENSCAFP00000007423 GO:0032869 biological_process cellular response to insulin stimulus
ENSCAFP00000007423 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
ENSCAFP00000007423 GO:0042593 biological_process glucose homeostasis
ENSCAFP00000007423 GO:0042953 biological_process lipoprotein transport
ENSCAFP00000007423 GO:0045165 biological_process cell fate commitment
ENSCAFP00000007423 GO:0045600 biological_process positive regulation of fat cell differentiation
ENSCAFP00000007423 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
ENSCAFP00000007423 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSCAFP00000007423 GO:0048469 biological_process cell maturation
ENSCAFP00000007423 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
ENSCAFP00000007423 GO:0050872 biological_process white fat cell differentiation
ENSCAFP00000007423 GO:0050873 biological_process brown fat cell differentiation
ENSCAFP00000007423 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSCAFP00000007423 GO:0055098 biological_process response to low-density lipoprotein particle
ENSCAFP00000007423 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
ENSCAFP00000007423 GO:0071285 biological_process cellular response to lithium ion
ENSCAFP00000007423 GO:0005634 cellular_component nucleus
ENSCAFP00000007423 GO:0005829 cellular_component cytosol
ENSCAFP00000007423 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
ENSCAFP00000007423 GO:0003677 molecular_function DNA binding
ENSCAFP00000007423 GO:0003682 molecular_function chromatin binding
ENSCAFP00000007423 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCAFP00000007423 GO:0003707 molecular_function steroid hormone receptor activity
ENSCAFP00000007423 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSCAFP00000007423 GO:0008144 molecular_function drug binding
ENSCAFP00000007423 GO:0008270 molecular_function zinc ion binding
ENSCAFP00000007423 GO:0019899 molecular_function enzyme binding
ENSCAFP00000007423 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSCAFP00000007423 GO:0033613 molecular_function activating transcription factor binding
ENSCAFP00000007423 GO:0043565 molecular_function sequence-specific DNA binding
ENSCAFP00000007423 GO:0046965 molecular_function retinoid X receptor binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10116 Rattus norvegicus 25664 13616 Monodelphis domestica 100026039
9796 Equus caballus 100051258 7029 Acyrthosiphon pisum 100166941
9483 Callithrix jacchus 100415661 61853 Nomascus leucogenys 100581046
30195 Bombus terrestris 100644185 10029 Cricetulus griseus 100689245
8128 Oreochromis niloticus 100711231 10141 Cavia porcellus 100725136
132113 Bombus impatiens 100744917 143995 Megachile rotundata 100876784
34638 Metaseiulus occidentalis 100899165 9305 Sarcophilus harrisii 100934154
30611 Otolemur garnettii 100943160 9597 Pan paniscus 100974825
9555 Papio anubis 101012073 39432 Saimiri boliviensis 101028278
9685 Felis catus 101095161 9595 Gorilla gorilla 101134077
9669 Mustela putorius furo 101688974 59463 Myotis lucifugus 102435787
10090 Mus musculus 19016 9913 Bos taurus 353106
9031 Gallus gallus 373928 9823 Sus scrofa 397671
7227 Drosophila melanogaster 39999 7460 Apis mellifera 410309
9598 Pan troglodytes 463188 7668 Strongylocentrotus purpuratus 580686
7070 Tribolium castaneum 660005 28377 Anolis carolinensis ENSACAG00000013360
9646 Ailuropoda melanoleuca ENSAMEG00000004774 9358 Choloepus hoffmanni ENSCHOG00000007152
51511 Ciona savignyi ENSCSAVG00000003303 7955 Danio rerio ENSDARG00000031848
9361 Dasypus novemcinctus ENSDNOG00000018641 10020 Dipodomys ordii ENSDORG00000003547
9365 Erinaceus europaeus ENSEEUG00000006334 9371 Echinops telfairi ENSETEG00000001775
69293 Gasterosteus aculeatus ENSGACG00000001665 8049 Gadus morhua ENSGMOG00000001375
7897 Latimeria chalumnae ENSLACG00000009212 9785 Loxodonta africana ENSLAFG00000030870
9315 Macropus eugenii ENSMEUG00000007824 9103 Meleagris gallopavo ENSMGAG00000013838
30608 Microcebus murinus ENSMICG00000016663 9544 Macaca mulatta ENSMMUG00000007191
9258 Ornithorhynchus anatinus ENSOANG00000006277 9986 Oryctolagus cuniculus ENSOCUG00000009353
9978 Ochotona princeps ENSOPRG00000003439 8090 Oryzias latipes ENSORLG00000004432
9813 Procavia capensis ENSPCAG00000001034 7757 Petromyzon marinus ENSPMAG00000008839
9601 Pongo abelii ENSPPYG00000013648 13735 Pelodiscus sinensis ENSPSIG00000011100
132908 Pteropus vampyrus ENSPVAG00000009845 42254 Sorex araneus ENSSARG00000009808
43179 Ictidomys tridecemlineatus ENSSTOG00000012778 37347 Tupaia belangeri ENSTBEG00000011278
59729 Taeniopygia guttata ENSTGUG00000004069 31033 Takifugu rubripes ENSTRUG00000015522
9478 Tarsius syrichta ENSTSYG00000006950 9739 Tursiops truncatus ENSTTRG00000016565
30538 Vicugna pacos ENSVPAG00000011059 8364 Xenopus tropicalis ENSXETG00000017422
8083 Xiphophorus maculatus ENSXMAG00000017330 99883 Tetraodon nigroviridis ENSTNIG00000014805